archive-org.com » ORG » E » EMMANET.ORG

Total: 93

Choose link from "Titles, links and description words view":

Or switch to "Titles and links view".
  • EMMA - the European Mouse Mutant Archive
    Initiative I3 combining in a closely co ordinated manner i Networking activities ii Trans national access and or service activities and iii Joint research activities All three categories of activities are mandatory as synergistic effects are expected from these different components Further details of I3 initiatives and TA activities are provided in the WORK PROGRAMME 2009 CAPACITIES PART 1 RESEARCH INFRASTRUCTURES European Commission C 2008 4566 of 26 August 2008 page 20 21 Networking activities EMMAservice will fully integrate three new partners into EMMA leading to a significantly increased archiving and distribution capacity and to the representation of a new member state in the network Outreach efforts to attract new EMMA users will be widened and will specifically target the human genetics and translational research communities Existing training courses in state of the art cryopreservation technologies will be continued and complemented with a new course format that aims to promote the shipment of frozen mouse resources Transnational Access activity EMMA s distribution service is based on a cost recovery system However EMMAservice will support eligible customers by providing free of charge Transnational Access to its mouse resources in response to a defined number of requests Joint research activities The main focus of the EMMAservice Joint Research Activities will be the cryopreservation of 1224 new mouse mutant lines The majority of this free of charge service will support strain donations from INDIVIDUAL RESEARCHERS but EuroMouse programmes such as EUCOMM EUMODIC MUGEN and FLPFLEX among others will also benefit EMMA s germ free service will support the generation of germ free mouse models and in addition maintain lines of general interest as live stocks in germ free conditions Live mice tissues or fluids from mouse lines introduced and or maintained in germ free housing will be distributed Technology development will underpin the

    Original URL path: http://strains.emmanet.org/projects/emmaservice-activities.php (2016-02-17)
    Open archived version from archive


  • EMMA - the European Mouse Mutant Archive
    entered Help NEWS About EMMA EMMA partners EMMA projects Introduction EMMAservice objectives EMMAservice activities EUCOMM EUMODIC WT Knockout Mouse Resource WTSI MGP INFRAFRONTIER FIMRe Costs Deposit mice Order mice EMMA axenic germ free service FAQs EMMA protocols Cryopreservation workshop Training courses Bibliography Links Internal Site EMMA projects European Conditional Mouse Mutagenesis Program EUCOMM Objectives Generation archiving and world wide distribution of an ES cell resource containing up to 13000 conditional mutations across the mouse genome in mouse embryonic stem ES cells Establishment archiving and world wide distribution of up to 320 mouse mutants from this resource Mutagenesis strategies Conditional gene trapping random approach for expressed genes Conditional targeted trapping directed approach used for expressed genes Conditional gene targeting directed approach used for non expressed genes Networking Generation of a European mouse functional genomics platform through the integration of EMMA EUMODIC EURExpress FLPFLEX EMAGE FunGenES PRIME and other programmes Member of the International Knockout Mouse Consortium IKMC acting as a cornerstone of world wide mouse mutagenesis effort in collaboration with the Canadian NorCOMM and the U S KOMP programmes Social benefits Improvement of health research Accelleration of clinical diagnosis drug development and therapy Competitive advantage for pharmaceutical industry Funding structure Funded

    Original URL path: http://strains.emmanet.org/projects/eucomm.php (2016-02-17)
    Open archived version from archive

  • EMMA - the European Mouse Mutant Archive
    germ free service FAQs EMMA protocols Cryopreservation workshop Training courses Bibliography Links Internal Site EMMA projects The European Mouse Disease Clinic EUMODIC A distributed phenotyping resource for studying human disease What is EUMODIC EUMODIC will bring together a large consortium of 18 research institutes in 8 European countries who are experts in the field of mouse functional genomics and phenotyping EUMODIC will undertake a primary phenotype assessment of up to 650 mouse mutant lines In addition a number of these mutant lines will be subject to an in depth secondary phenotype assessment Mutant lines will be made available from the EUCOMM European Conditional Mouse Mutagenesis project which aims to produce conditional mutations in 13000 mouse genes In addition a number of these mutant lines will be subject to a more in depth secondary phenotype assessment What are the aims of EUMODIC The EUMODIC consortium will build on the work in the EUMORPHIA project that delivered a comprehensive database EMPReSS of Standard Operating Procedures SOPs that can be used to determine the phenotype of a mouse EUMODIC has developed a selection of these screens called EMPReSSslim which is structured for comprehensive primary high throughput phenotyping of large numbers of mice Primary

    Original URL path: http://strains.emmanet.org/projects/eumodic.php (2016-02-17)
    Open archived version from archive

  • EMMA - the European Mouse Mutant Archive
    Deposit mice Order mice EMMA axenic germ free service FAQs EMMA protocols Cryopreservation workshop Training courses Bibliography Links Internal Site EMMA projects Wellcome Trust Knockout Mouse Resource The Wellcome Trust has negotiated and funded the acquisition of a limited number of gene knockout mouse strains and associated phenotypic data from Deltagen Inc and Lexicon Pharmaceuticals This resource will be archived and distributed through EMMA and provides researchers with unprecedented access to two private collections of knockout mice These valuable models will not only aid the study of human disease but will also form part of a genome wide library of knockout mice Comprehensive information on such a large group of mouse strains has never been available to public sector researchers before and is expected to accelerate the discovery of functional genes effecting human health and disease Under the terms of the world wide academic licence granted to the Trust for the use of the mouse lines by Deltagen and Lexicon researchers will be able to share the mouse lines acquired with other academic collaborators To assist the Wellcome Trust in tracking the outputs of the research to which it has contributed either wholly or in part the Trust s contributions

    Original URL path: http://strains.emmanet.org/projects/wt-kmr.php (2016-02-17)
    Open archived version from archive

  • EMMA - the European Mouse Mutant Archive
    Links Internal Site EMMA projects Wellcome Trust Sanger Institute Mouse Genetics Project MGP The Sanger Institute s mouse genetics group is running an extensive sequence phenotype driven mutagenesis programme as part of an international effort aimed at mutating over 95 percent of known mouse genes in embryonic stem cells by 2011 The mice generated by the programme will be made freely available to the scientific community as they are generated

    Original URL path: http://strains.emmanet.org/projects/wt-mgp.php (2016-02-17)
    Open archived version from archive

  • EMMA - the European Mouse Mutant Archive
    Links Internal Site EMMA projects INFRAFRONTIER The INFRAFRONTIER project will organize two complementary and linked infrastructure networks for large scale and comprehensive phenotyping and archiving of mouse models This project will serve the European genetics and biomedical research community for the benefit of human health INFRAFRONTIER integrates 15 European laboratories with exceptional track records in the integration and running of large scale infrastructures INFRAFRONTIER will build on existing infrastructures developed

    Original URL path: http://strains.emmanet.org/projects/infrafrontier.php (2016-02-17)
    Open archived version from archive

  • EMMA - the European Mouse Mutant Archive
    Centers worldwide whose collective goal is to archive and provide strains of mice as cryopreserved embryos and gametes ES cell lines and live breeding stock to the research community Goals of the Federation of International Mouse Resources Coordinate repositories and resource centers to archive valuable genetically defined mice and ES cell lines being created worldwide meet research demand for these genetically defined mice and ES cell lines Establish consistent highest quality animal health standards in all resource centers Provide genetic verification and quality control for genetic background and mutations Provide resource training to enhance user ability to utilize cryopreserved resources FIMRe Charter FIMRe publication FIMRe Board of Directors FIMRe Federation of International Mouse Resources Global Networking of Resource Centers 2006 Mammalian Genome 17 363 364 PubMed Members of the Federation of International Mouse Resources North America The Jackson Laboratory Bar Harbor ME TJL Mouse Mutant Resource Regional Centers MMRRC includes University of North Carolina Chapel Hill NC University of California Davis CA University of Missouri and Harlan Columbia MO Mouse Models of Human Cancer Consortium Frederick MD MMHCC Canadian Mouse Consortium CMC Canadian Mouse Mutant Repository Toronto Ontario CMMR Europe European Mouse Mutant Archive EMMA includes CNR Istituto di Biologia

    Original URL path: http://strains.emmanet.org/projects/fimre.php (2016-02-17)
    Open archived version from archive

  • EMMA - the European Mouse Mutant Archive
    About EMMA EMMA partners EMMA projects Costs EMMA procedures costs Legal restrictions Health monitoring Ethics Deposit mice Order mice EMMA axenic germ free service FAQs EMMA protocols Training courses Bibliography Links Internal Site EMMA procedures Costs Costs for archiving Transport of submitted mice to EMMA will be the responsibility of the depositor No charge will be levied for archiving services quarantine re derivation cryopreservation SPF breeding etc Costs for distribution Standard fees Shipments of frozen embryos sperm cost 1100 while live mice are distributed for a cost of 2400 The 2400 covers the provision of a breeding nucleus of up to three pairs of SPF mice The charges levied by EMMA are used solely to meet the animal husbandry and stock replacement costs Customers are still asked to meet the actual costs for shipping the material from the EMMA facility to the recipient s institution As the default heterozygous material is being archived and distributed EMMA does not generally offer breeding services to e g generate cohorts of homozygous mutants However such a service and fees may be negotiated with the respective EMMA distribution centre In general service requests will not be processed until a fully executed Material Transfer Agreement

    Original URL path: http://strains.emmanet.org/procedures/costs.php (2016-02-17)
    Open archived version from archive



  •