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  • EMMA - the European Mouse Mutant Archive
    the Sanger Institute The projects EMMA is involved in will lead to a significant growth of the EMMA archive in the coming years Sustainable funding and the development of two complementary and linked infrastructure networks for large scale and comprehensive phenotyping and archiving of mouse models will be addressed by the INFRAFRONTIER project Global distribution of the mouse mutant lines stocked in EMMA is aided by the participation of the

    Original URL path: http://strains.emmanet.org/projects/projects-intro.php?style=print& (2016-02-17)
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  • EMMA - the European Mouse Mutant Archive
    humans Provide reliable access to mouse models and associated data To exploit the resources emerging from initiatives such as the International Knock Out Mouse Consortium IKMC mouse models must be preserved and made available to the entire European biomedical research community which is wholly dependent on new mouse models of human disease Building on EMMA s previous achievements as the primary mouse repository in Europe EMMAservice aims to meet the future challenges presented by archiving and disseminating mouse models in the ERA as follows Archiving of 1224 new mouse mutant lines in support of individual depositors and also European mouse genetics programmes Support of eligible customers with free of charge Transnational Access for up to 20 of requested mouse resources Technology development will underpin the archiving and distribution efforts by advancing current sperm freezing technology Training courses will promote the shipment of frozen germplasm rather than live mice EMMA informatics will support user services by setting new standards for user friendly access to EMMA services extensive data curation and cross referencing with other mouse database resources Outreach efforts to attract users will be widened and directed towards the translational research community EMMAservice will contribute significantly to the development of a

    Original URL path: http://strains.emmanet.org/projects/emmaservice.php?style=print& (2016-02-17)
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  • EMMA - the European Mouse Mutant Archive
    and partial terms can be entered Help NEWS About EMMA EMMA partners EMMA projects Introduction EMMAservice objectives EMMAservice activities EUCOMM EUMODIC WT Knockout Mouse Resource WTSI MGP INFRAFRONTIER FIMRe Costs Deposit mice Order mice EMMA axenic germ free service FAQs EMMA protocols Cryopreservation workshop Training courses Bibliography Links Internal Site EMMA projects EMMAinf European Mouse Mutant Archive Infrastructure EMMAinf was a project of 4 5 years duration July 2004 December 2008 and funded by the EC FP6 Infrastructures Program Seven partners of the EMMA network participated in the EMMAinf project The EMMAinf partners and their roles in the project are summarised in the table below The EMMAinf objectives are described on the following page EMMAinf project partners Tasks Consiglio Nazionale delle Ricerche Istituto di Biologia Cellulare CNR IBC in Monterotondo EMMA core facility embryo cryopreservation distribution cryopreservation courses CNRS Centre de Distribution de Typage et d Archivage animal CNRS CDTA in Orléans Embryo cryopreservation distribution cryopreservation courses MRC Mammalian Genetics Unit MRC MGU in Harwell Sperm and embryo cryopreservation distribution cryopreservation courses Karolinska Institute KI in Stockholm Embryo cryopreservation distribution production of germ free axenic mice Fundação Calouste Gulbenkian FCG in Oeiras Production of germ free axenic mice Helmholtz Zentrum

    Original URL path: http://strains.emmanet.org/projects/emmainf.php (2016-02-17)
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  • EMMA - the European Mouse Mutant Archive
    new member state in the network Outreach efforts to attract new EMMA users will be widened and will specifically target the human genetics and translational research communities Existing training courses in state of the art cryopreservation technologies will be continued and complemented with a new course format that aims to promote the shipment of frozen mouse resources Transnational Access activity EMMA s distribution service is based on a cost recovery system However EMMAservice will support eligible customers by providing free of charge Transnational Access to its mouse resources in response to a defined number of requests Joint research activities The main focus of the EMMAservice Joint Research Activities will be the cryopreservation of 1224 new mouse mutant lines The majority of this free of charge service will support strain donations from INDIVIDUAL RESEARCHERS but EuroMouse programmes such as EUCOMM EUMODIC MUGEN and FLPFLEX among others will also benefit EMMA s germ free service will support the generation of germ free mouse models and in addition maintain lines of general interest as live stocks in germ free conditions Live mice tissues or fluids from mouse lines introduced and or maintained in germ free housing will be distributed Technology development will underpin

    Original URL path: http://strains.emmanet.org/projects/emmaservice-activities.php?style=print& (2016-02-17)
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  • EMMA - the European Mouse Mutant Archive
    genes Conditional gene targeting directed approach used for non expressed genes Networking Generation of a European mouse functional genomics platform through the integration of EMMA EUMODIC EURExpress FLPFLEX EMAGE FunGenES PRIME and other programmes Member of the International Knockout Mouse Consortium IKMC acting as a cornerstone of world wide mouse mutagenesis effort in collaboration with the Canadian NorCOMM and the U S KOMP programmes Social benefits Improvement of health research

    Original URL path: http://strains.emmanet.org/projects/eucomm.php?style=print& (2016-02-17)
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  • EMMA - the European Mouse Mutant Archive
    mouse genes In addition a number of these mutant lines will be subject to a more in depth secondary phenotype assessment What are the aims of EUMODIC The EUMODIC consortium will build on the work in the EUMORPHIA project that delivered a comprehensive database EMPReSS of Standard Operating Procedures SOPs that can be used to determine the phenotype of a mouse EUMODIC has developed a selection of these screens called

    Original URL path: http://strains.emmanet.org/projects/eumodic.php?style=print& (2016-02-17)
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  • EMMA - the European Mouse Mutant Archive
    been available to public sector researchers before and is expected to accelerate the discovery of functional genes effecting human health and disease Under the terms of the world wide academic licence granted to the Trust for the use of the mouse lines by Deltagen and Lexicon researchers will be able to share the mouse lines acquired with other academic collaborators To assist the Wellcome Trust in tracking the outputs of

    Original URL path: http://strains.emmanet.org/projects/wt-kmr.php?style=print& (2016-02-17)
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  • EMMA - the European Mouse Mutant Archive
    by 2011 The mice generated by the programme will be made freely available to the scientific community as they are generated with minimal material transfer agreement conditions All mutant mouse lines generated at the Wellcome Trust Sanger Institute will be examined using a common battery of phenotyping tools and the data published on this website The intention is to associate the loss of function of genes mutations with disease processes

    Original URL path: http://strains.emmanet.org/projects/wt-mgp.php?style=print& (2016-02-17)
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