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  • 14th International Mouse Genome Conference (2000)
    draft sequence of the human genome in June 2000 was generally regarded as an iconic moment Why The data after all was already in the public databases and was being searched and analysed by tens of thousands of scientists in academia and industry But quite correctly people perceived that humanity had gained a new and unprecedented power over its own destiny not simply from the sequence but from the cumulative work of molecular biology during half a century It is time for society to take stock of the way the information should be handled There are huge potentials for discovery and invention for improving medical care and for wealth creation There are also issues of human rights if the information is not handled appropriately The vast majority of the sequence is now available More than a quarter is finished including two complete chromosomes and the rest has good coverage though not long range continuity We can now see the entire landscape of base composition and repeated sequences for the first time First pass analysis indicates fewer genes than expected about 40000 now looks a likely number The predicted proteins have few novel domains relative to invertebrates but they do have

    Original URL path: http://www.imgs.org/Archive/abstracts/2000abstracts/VCMLIIjes_IMGC.shtml (2016-02-17)
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  • International Mammalian Genome Society 1999 Abstracts
    Mb Imprinted Domain in Mouse Chromosome 7C Homologous to Human 15q11 q13 and Prader Willi Syndrome T Ohta D P Locke T A Gray J M Gabriel E M Rinchik M S Dhar D K Johnson Y Ji M T C Jong R Longnecker B T Lamb R D Nicholls Methylation is Acquired at Different Times on the Maternal and Paternal H19 Alleles During Male Germ Cell Development Tamara L Davis Grace J Yang John McCarrey and Marisa S Bartolomei Function of Mouse Brahma Genes During Development S J Bultman J Mager F Randazzo G R Crabtree R Krumlauf and T R Magnuson The Mechanisms of Gene Silencing in Genomic Imprinting Amy T Hark Christopher J Schoenherr David Katz Michele A Cleary and Shirley M Tilghman Interactive Poster Session Characterisation of a Putative Imprinting Control Element Which Lies Between the Imprinted Igf2 and H19 Genes in the Mouse Marika Charalambous and A War Sex of Offspring Specific Transmission Ratio Distortion on Mouse Chromosome X Elena de la Casa Esperon Fernando Pardo Manuel de Villena Andrei E Verner Tammi L Briscoe Jan Michel Malette Michelle Rosa Wen Hui Jin and Carmen Sapienz Genomic Organization of the Imprinted Mouse Gene RasGrf1 Aranzazu de la Puente and Christoph Plass Evidence of a Paternally Imprinted Gene Affecting Body Weight in Mice on Mouse Chromosome 7 Madhu Dhar Lisa Webb Laurel Smith David West and Dabney Johnson Characterization of a New Imprinted Domain in Proximal Mouse Chromosome 7 Human Chromosome 19q13 4 Joomyeong Kim Anne Bergmann Xiaochen Lu Elbert Branscomb and Lisa Stubbs Effects of X Chromosome Number and Parental Origin on X Linked Gene Expression in Preimplantation Mouse Embryos Keith E Latham Bela Patel F Dale M Bautista and Susan M Hawes Regulation of Imprinted Gene Expression in the Preimplantation Embryo Mellissa Mann Adam

    Original URL path: http://www.imgs.org/Archive/abstracts/99abstracts/toc_a.shtml (2016-02-17)
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  • International Mammalian Genome Society 1999 Abstracts
    Alleles Allan Peter Davis Cathleen M Lutz Richard M Baldarelli Judith A Blake Janan T Eppig and Staff of Mouse Genome Informatics The Language of Phenotypes Bringing Sandard and Mutant Phenotype Vocabularies Into MGD Janan T Eppig Judith A Blake Richard M Baldarelli Allan P Davis Cathy M Lutz and Joel E Richardson MOUSE GENOME INFORMATICS MGI OLD FAVORITES NEW HITS J A Kadin J E Richardson J T Eppig J A Blake M Ringwald and the Mouse Genome Informatics Staff The Mouse Tumor Biology Database MTB Project Cathleen M Lutz Debra M Krupke Carol J Bult John P Sundberg Janan T Eppig What s New in Nomenclature Lois J Maltais Judith A Blake Janan T Eppig Muriel T Davisson Map Manager QTX Cross Platform Software for Mapping Quantitative Trait Loci Kenneth F Manly none Rat Genome Data Genetic Markers Polymorphisms and Maps Palazola Richard P Kadin James A Richardson Joel E Eppig Janan T Tools for EST Mapping Patricia Rodriguez Tome Cross Referencing the T31 Whole Genome Radiation Hybrid Data to the High Quality Recombination Map of the Mouse Lucy Rowe Mary Barter Jurgen Naggert Janan Eppig Mutabase A Distributed Database for Animal Husbandry Mutagenesis and Behavioural Analysis Strivens

    Original URL path: http://www.imgs.org/Archive/abstracts/99abstracts/toc_b.shtml (2016-02-17)
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  • International Mammalian Genome Society 1999 Abstracts
    Structure Bioinformatics Sequence Mapping New Tools Gene Discovery Developmental Mutagenesis Functional Genomics C Genome Sequence and Comparative Sequence Analysis Presentations Biological Annotation of Drosophila Genome Sequence Gerald M Rubin Comparative Vertebrate Genomics Elbert Branscomb The Joint Genome Institute Walnut Creek CA no abstract available Genes and Genomics Erick Lander The Whitehead Institute Cambridge MA no abstract available Comparative Mouse Genome Sequencing for Systematic Studies of Mammalian Gene Function Steve Brown

    Original URL path: http://www.imgs.org/Archive/abstracts/99abstracts/toc_c.shtml (2016-02-17)
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  • International Mammalian Genome Society 1999 Abstracts
    Nicholas Levy Alexander Agulnik M Teresa Ty Yoshitake Nishimune and Colin Bishop Development of a Genetic and Physical Map of the Region of Mouse Chromosome 8 Homologous to the Facioscapulohumeral Muscular Dystrophy Locus on Human Chromosome 4q35 Cloning of an Evolutionary Chromosomal Breakpoint D J Bolland P K Grewal M van Geel R R Frants P J de Jong J E Hewitt Comparative Sequence Analysis of the Caltractin Region in Man Mouse and Fugu Marc Botcherby E Vithana and M S Clark Archiving and Recovery of Bacterial Plasmids Using FTA Paper Michael Connolly Pamela Hansen Arubula Reddy and Mindy Goldsborough Genetic and Physical Maps of the Mouse del36H Deletion Paul Denny Matthew Cadman Tracy Marsland Ruth Arkell Owen McCann Lucy Matthews Sarah Sims Stephan Beck Jane Rogers Steve Brown Genomic Structure of the Mouse Ap3b1 Gene Brian W Rigatti Lijun Feng Edward K Novak Richard T Swank and Michael B Gorin Determination of Exon Intron Boundaries by Direct Sequencing of BACs with Internal Primers Lijun Feng Edward K Novak and Richard T Swank Novel Alternatively Spliced Form of Nbr1 Redefines Brcal Nbr1 Intergenic Region with Putative Bi Directional Promoter Conserved in Human and Rodents Stoil Dimitrov Maria Brennerova and Jiri Forejt Comparative Sequence Analysis of the Region from RSVP to F8 on Mouse Chromosome X and its Syntenic Region in Human Xq28 Galgoczy P Reichwald K Goremykin V Geist S Rosenthal A Platzer M Megasatellite DNA Human RS447 and Its Homologs in Rodents Yoichi Gondo Yoshinori Okada Takeya Okada Yasushi Saitoh Yoshiko Yanagisawa Joh E Ikeda The Mouse Full Length cDNA Encyclopedia Jun Kawai Yoshifumi Fukunishi Piero Carninci Yuichi Sugahara Masayasu Yoshino Yasuhiro Ozawa Kazuhiro Shibata Masayoshi Itoh Yuko Shibata Hideaki Konno Toshinori Endo Masami Muramatsu Yasushi Okazaki and Yoshihide Hayashizaki Prediction of Regulatory Regions Sequence and Computational Analysis of

    Original URL path: http://www.imgs.org/Archive/abstracts/99abstracts/toc_d.shtml (2016-02-17)
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  • International Mammalian Genome Society 1999 Abstracts
    and Brown Adipocyte Formation in Mouse Retroperitoneal White Fat Robert A Koza Susanna Hohmann Lana Ritchie James Mancuso and Leslie P Kozak Identification of Dietary Response Genes Involved in Lipid Metabolism and Susceptibility to Atherosclerosis in Mice Arja J Kreeft Corina J A Moen Patrick J J van Gorp Nicole A Datson Marion J J Gijbels Miek C Jong Erno Vreugdenhil Rune R Frants Louis M Havekes and Marten H Hofker High Resolution Mapping of QTL for Body Weight in Mice by Progeny Testing Xiaojun Liu and Peter Keightley A Four Locus Least Squares Linear Genetic Model of Testosterone Production by Leydig Cell in Mice Osadchuk A V Svechnikov K V and Ahmerova L G Quantitative Trait Loci Analysis of Salt Induced Blood Pressure Elevation in C57BL 6J and A J Mice Concordance of QTL with Rat and Human Hypertension QTL Beverly Paigen Fumihiro Sugiyama Gary A Churchill David Higgins Conrado Johns and Haralambos Gavras Genetic and Functional Analysis of QTL that Modulate the Endotoxin Induced Flammatory Response L E Matesic E L Niemitz A De Maio and R H Reeves Mapping and Positional Cloning of TNF Response Modifier Genes in the Mouse Ben Wielockx Jan Staelens Rosemary Elliott and Claude Libert Mapping Germ Cell Tumor Susceptibility Genes Using a Consomic Strain and Derived Congenic Strains Kirsten Youngren Angabin Matin and Joseph Nadeau QTL Mapping Posters Body Weight Food Water and Salt Consumption in 28 Mouse Strains A A Bachmanov M G Tordoff and G K Beauchamp Seizure Susceptibility from a Locus on Chromosome 1 Gene Candidates for Szs1 R J Buono T N Ferraro M R Sperling M J O Connor S G Ryan G T Golden G G Smith and W H Berrettini Viral Load and a Locus on Chromosome 11 Affect the Late Clinical Disease Caused by Theiler s Virus Stéphanie Aubagnac Michel Brahic and Jean François Bureau Isolation Characterization and Analysis of p140mRhoGAP Michael R Crowley Karen E Slon Norma J Nowak Kazutoyo Osoegawa Pieter DeJong and Bonnie B Asch Comparison of Bone Mineral Content and Bone Mineral Density in C57BL 6J and C3H HeJ Female Mice by pQCT Stratec XCT 960M and DEXA PIXImus L R Donahue C J Rosen and W G Beamer Unexpectedly High Recombination Frequency in a Cross Involving an Interspecies Congenic Strain on Chr X During Genetic Analysis of Male Hybrid Subfertility Rosemary W Elliott Darla R Miller R Scott Pearsall Colleen Hohman Diane Poslinski Debra A Tabaczynski Verne M Chapman Profiling Movement Patterns in the Development of Neurological Mutant Mice John C Fentress Szs1 A Fundamental Seizure Related Locus on Mouse Chromosome 1 T N Ferraro G T Golden G G Smith P St Jean N J Schork R J Buono and W H Berrettini Dysfunctional Intestine and Abnormality in CNS Found in XPG Deficient Mice Yoshi nobu Harada Xue Zhi Sun Atsushi Tsuji Naoko Shiomi Tadahiro Shiomi The MPTP Mouse Model as Tool for Revealing the Genetics of Parkinson s Disease K Hofele M Sedelis S Morgan P Kutz

    Original URL path: http://www.imgs.org/Archive/abstracts/99abstracts/toc_e.shtml (2016-02-17)
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  • International Mammalian Genome Society 1999 Abstracts
    John Schimenti and Yun You Genomic Characterization and Targeted Mutagenesis of Lysophosphatidic Acid Receptor Genes lp A1 lp A2 lp A3 James J A Contos and Jerold Chun Genetic Analysis of the Regulatory System Controlling the Induction of Brown Adipocytes in White Fat Tissues Ann Allen Coulter Robert A Koza Wolfgang Hofmann and Leslie P Kozak Cloning and Characterization of Glas 1 A Novel Gene Associated with Mouse Osteopetrosis Mathieu Ferron Hugues Bernard and Jean Vacher Fine Mapping and FISH Analysis of a Mouse T 2 13 Translocation Causing Neurological Coat Color and Developmental Abnormalities Mary Guarnieri Nestor Cacheiro and Lorraine Flaherty An Integrated Genetic and Physical Map Around the Doublefoot Locus on Mouse Chromosome 1 Christopher Hayes Mark Harrison Gillian Morriss Kay Mary Lyon Steve DM Brown Altered Expression of Pten is an Essential Event in Mouse Thymic Lymphomagenesis Michel Herranz Javier Santos Mónica Fernández Janet Reyes Concepción Vaquero and José Fernández Piqueras Characterization of a Phenocopy of Waved Mice Bruce Herron Lisa Pacella Dorothee Foernzler Cherie VanDoren and David Beier Isolation and Evaluation of Candidate Genes for the High Growth hg Mutation in Mice Simon Horvat Jim McWhir Brad A Freking Juan F Medrano Mutation in the cb A3 A1 Crystallin Encoding Gene Cryba1 Causes a Dominant Cataract in the Mouse J Graw J Löster A Reis E Wolf R Balling M Hrabé de Angelis Functional and Genetic Analyses of the Jerker je Mouse Mutant Torrance K Jackson and Konrad Noben Trauth Three New Allelic Mouse Mutations that Cause Skeletal Overgrowth Involve the Natriuretic Peptide Receptor C Gene Npr3 Jean Jaubert Francis Jaubert Natalia Martin Linda L Washburn Barbara K Lee Eva M Eicher and Jean Louis Guenet Mapping and Manipulation of the Murine Ryanodine Receptor Locus Ryr1 P Kathirvel E Hitchin R Ansell J McWhir J D Ansell and A L Archibald Alymphoplasia is Caused by a Point Mutation in NF Kappa B Inducing Kinase NIK Gene Kazuhiro Kitada Reiko Shinkura Fumihiko Matsuda Kei Tashiro Kouichi Ikita Katsumi Kogishi Misao Suzuki Sigeki Miyawaki Tasuku Hpnjo Tadao Serikawa Progress in Genetic and Functional Characterization of Two Mouse Deafness Mutants pirouette and spinner David C Kohrman Hana Odeh Kristina Hunker Ellen Hibbard Lisa Beyer Gary Dootz Nobuko Hagiwara Murray H Brilliant David F Dolan and Yehoash Raphael Positional Cloning of Two Tumor Suppressor Genes Involved in Gamma Ray Induced Mouse Thymic Lymphomas Kominami R Okano H Matsuki A Wakabayashi Y Shinbo T Kosugi S Takahashi Y and Niwa O p53 modifiers near the D16Mit181 locus on chromosome 16 and in the vicinity of D19Mit123 on chromosome 19 Saito Y Matsuki A Wakabayashi Y Kosugi S Takahashi Y and Niwa O and Kominami R Localization of a Breakpoint of Chromosomal Inversion Responsible for the Hairy Ears Eh Mutation Tetsuo Kunieda Izumi Ojika Miyuki Nakamura Positional Cloning of the Flexed Tail Locus Laurie E Lenox and Robert F Paulson The stargazer Gene Product is One Member of a Family of Gamma Subunits of Voltage Dependent Calcium Channels Verity A Letts Connie

    Original URL path: http://www.imgs.org/Archive/abstracts/99abstracts/toc_f.shtml (2016-02-17)
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  • International Mammalian Genome Society 1999 Abstracts
    and Eva M Eicher Developmental Profile of Abnormal Cerebellar Development in Ts65Dn Mice Laura L Baxter and Roger H Reeves Telling Time Lunatic Fringe and Somite Segmentation Susan E Cole John M Levorse and Thomas F Vogt Strain Dependent Craniofacial and Neural Tube Defects in Ski Deficient Mice Clemencia Colmenares Edward Stavnezer Stuart Schwartz and Natalia Lerner Positional Cloning of the exma Locus an X Linked Insertional Mutation Causing Exencephaly and Microphthalmia Anophthalmia David Cunningham Qiang Xiao Aurobindo Chatterjee Kathleen Sulik Diana Juriloff Frederick Elder Wilbur Harrison Gabriele Schuster Paul Overbeek Gail E Herman Transcript Mapping in the Lp Critical Region on Mouse Chromosome 1 Kit Doudney Jane Eddleston Claire Braybrook Aysha Itani Muly Tham Jennifer Murdoch Andrew Copp and Philip Stanier Characterisation of Transgenic Mice Overexpressing the Wilms Tumour Protein WT1 James Dutton and Andrew Ward The Proximal Albino Deletions Identify Genes Essential for Anterior Posterior Axis Specification and Development of Several Neuroendocrine Lineages of the Hypothalamus Mary E Wines Kristen Brown Jacques L Michaud Charles De Rossi Stephen Wefer Lance Lee Tom Rosenquist Noah R May Chen Ming Fan and Bernadette C Holdener Neuronal Diversity and Differentiation in the Mouse Embryo Requires the Delta like Gene 1 Kurt Wünsch Ulrich Heinzmann Achim Gossler and Martin Hrabé de Angelis Molecular and Genetic Control of Mouse Primordial Germ Cell Development Lily Jiang and Joseph Nadeau Sex Specific Effects of ENU Induced Steel Mutations on Germ Cell Development A Mahakali L B Russell N G Copeland N A Jenkins and M A Bedell Evidence for a Lack of Sharing of SPAM1 Among Spermatids and Transmission Ratio Distortion Ying Zheng Xiangning Deng and Patricia A Martin DeLeon Mapping of Modifier Gene for Mouse Preaxial Polydactylous Mutantion Rim4 Hiroshi Masuya Tomoko Sagai Motohisa Takahashi Toshihiko Ogura and Toshihiko Shiroishi Expression of Jagged1 During

    Original URL path: http://www.imgs.org/Archive/abstracts/99abstracts/toc_g.shtml (2016-02-17)
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