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  • 18th International Mouse Genome Conference (2004)
    Philadelphia Philadelphia United States 37 SUPPRESSORS AND ENHANCERS OF TESTICULAR CANCER SUSCEPTIBILITY IN DOUBLE MUTANT MICE Lam MYJ Youngren KK Nadeau JH Case Western Reserve University Cleveland United States 38 MODIFIERS OF THE DDK SYNDROME RESULT IN THE DOMINANT RESCUE OF EMBRYONIC LETHALITY Ideraabdullah FY Kim K Pardo Manuel de Villena F Dept of Genetics UNC Chapel Hill Chapel Hill United States 39 THE REQUIREMENT FOR EED IN AUTOSOMAL GENOMIC IMPRINTING MAY BE TISSUE SPECIFIC Chamberlain SJ Montgomery ND Kalantry S Magnuson T Department of Genetics University of North Carolina Chapel Hill Chapel Hill NC United States 40 PREDISPOSITION TO MOUSE THYMIC LYMPHOMAS DEPENDS ON COMMON VARIANT ALLELES OF MTF 1 METAL RESPONSIVE TRANSCRIPTION FACTOR 1 Kominami R 1 Tamura Y 1 Maruyama M 1 Mishima Y 1 Schaffner W 2 1 Niigata University Graduate School of Medical and Dental Sciences Niigata Japan 2 Institute for Molecular Biology University of Zurich Zurich Switzerland 41 EVOLUTIONARILY CONSERVED SEQUENCE ELEMENTS THAT POSITIVELY REGULATE INTERFERON GAMMA EXPRESSION IN T CELLS Shnyreva M 1 Weaver WM 1 Blanchette M 3 Taylor SL 2 Fitzpatrick DR 2 Tompa M 1 Wilson CB 1 1 University of Washington Seattle United States 2 Amgen Corporation Seattle United States 3 McGill University Montreal Canada 42 MODIFIER LOCI THAT INFLUENCE TPA SKIN TUMOR PROMOTION SUSCEPTIBILITY IN GENETIC CROSSES OF DBA 2 WITH C57BL 6 MICE Angel JM Abel EL Riggs PK Elizondo L Caballero M DiGiovanni J Univ Texas MD Anderson Cancer Center Science Park Research Division Smithville United States 43 MOUSE HAIRY EARS EH INVERSION MUTATION DISRUPTS NO GENE TRANSCRIPTS BUT EXPRESSION OF HOXC GENES IN SKIN IS DISTURBED Mentzer S 1 Sundberg J 2 Cacheiro N 1 Chao H 3 Carpenter D 1 Johnson D 1 Rinchik E 3 You Y 1 1 Oak Ridge National Laboratory Oak Ridge United States 2 The Jackson Laboratory Bar Harbor United States 3 University of Tennessee Knoxville United States 44 DEVELOPMENTAL PROFILE OF DNA METHYLATION AND GENE EXPRESSION AT THE H19 LOCUS IN MICE LACKING SEQUENCE REQUIRED FOR GENOMIC IMPRINTING Thorvaldsen J Fedoriw A Yang G Bartolomei M University of Pennsylvania Philadelphia United States 45 CURRENT PROGRESS IN SCREENING FOR MUTANTS AFFECTING GENOMIC IMPRINTING IN THE RIKEN GSC PROJECT Suzuki T 1 Furuumi H 2 Hashimoto M 3 Kyouno S 4 Nagashima A 1 Kumaki K 2 Kaneda H 1 Gondo Y 5 Noda T 1 Wakana S 1 Ishino F 4 Sasaki H 2 Shiroishi T 1 1 Mouse Functional Genomics Research Group Genomics Science Center GSC RIKEN Yokohama Institute Yokohama Japan 2 Department of Integrated Genetics National Institute of Genetics Mishima Japan 3 Gene Research Center Tokyo Institute of Technology Yokohama Japan 4 Department of Epigenetics Medical Research Center Tokyo Medical and Dental University Tokyo Japan 5 Population and Quantitative Genomics Team GSC RIKEN Yokohama Japan 46 ANALYSIS OF THE CANDIDATE REGION AND CANDIDATE GENES RESPONSIBLE FOR THE DDK SYNDROME OF EMBRYONIC LETHALITY de la Casa Esperon E 1 Gimelbrant A 3 Adey B 1 Briscoe T 1

    Original URL path: http://www.imgs.org/Archive/abstracts/2004abstracts/toc4.shtml (2016-02-17)
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  • 18th International Mouse Genome Conference (2004)
    OF GENE EXPRESSION AT THE DEL 13 SVEA36H REGION OF MOUSE CHROMOSOME 13 DURING POSTIMPLANTATION MOUSE DEVELOPMENT Willoughby C 1 Davies J 1 Underhill P 1 Holmes C 1 Greenfield A 1 Denny P 1 Ragoussis J 2 Arkell R 1 1 Mammalian Genetics Unit MRC Harwell Oxfordshire United Kingdom 2 Wellcome Trust Centre for Human Genetics Oxford United Kingdom 66 MAPPING AND POSITIONAL CLONING OF ENU INDUCED MOUSE DEVELOPMENTAL MUTANTS WITH A WHOLE GENOME SNP PANEL AND EXON BASED SEQUENCING Moran JL 1 Yun Y 1 Brown A 1 Bjork BC 1 Tran P 1 Li C 2 Salinger AP 3 Poirier C 3 Zhang B 1 Montgomery K 1 Bishop C 3 Justice M 3 Wiltshire T 4 Kwiatkowski DJ 1 Kucherlapati R 1 Beier DR 1 1 Brigham and Women s Hospital Harvard Medical School Boston MA United States 2 Dana Farber Cancer Institute Harvard School of Public Health Boston MA United States 3 Baylor College of Medicine Houston TX United States 4 Genomics Institute of the Novartis Research Foundation San Diego CA United States 67 PHENOTYPE OR GENOTYPE THE ORGANISM FROM DIFFERENT BIOLOGICAL PERSPECTIVES Eppig JT van den Borre P Lu I Anagnostopoulos A Burkart DL Cassell MA Dene H Bello SM Washburn LL Lutz CM Goldsmith CW Smith CL The Jackson Laboratory Bar Harbor United States 68 SOPDB A RESOURCE OF STANDARD OPERATING PROCEDURES FOR MOUSE PHENOTYPING Green ECJ Gkoutos GV Weekes J Mallon AM Hancock JM Mammalian Genetics Unit Oxfordshire United Kingdom 69 STUDY OF THE GENES INVOLVED IN THE HYPERTROPIC LANGERHANS ISLAND OF THE KK A Y MOUSE AND THEIR HISTOLOGICAL LOCALIZATION Kusakabe M 1 Matsuba K 2 Inoue J 2 Aotsuka S 2 Hokao R 1 Hashimoto H 3 1 Institute for Animal Reproduction Ibaraki Japan 2 ANB Tsukuba Institute Aloka Co Ltd Ibaraki Japan 3 Jikei Univ Sch of Med Dept Anat Tokyo Japan 70 IDENTIFICATION AND LOCALISATION OF MUTATIONS IN THE DEL 13 SVEA36H DELETION McKeone R Rowe C Polley S Wells S Arkell R Davies J Bogani D Dear N Denny P MRC Harwell Didcot United Kingdom 71 BEHAVIORAL CHARACTERIZATION AND LINKAGE ANALYSIS OF AN ENU INDUCED MOUSE MUTANT LINE THAT SHOWS LEARNING DEFICIT REDUCTION OF BODY SIZE CONVULSIVE SEIZURE AND TRANSIENT IMMOBILITY Furuse T Wada Y Masuya H Kaneda H Kobayashi K Kawai A Kushida T Nishii R Gondo Y Noda T Wakana S Shiroishi T RIKEN GSC Tsukuba Japan 72 THE NOX3 AND NOXO1 GENES ENCODING PRESUMPTIVE MEMBERS OF AN NADPH OXIDASE COMPLEX ARE REQUIRED FOR NORMAL VESTIBULAR FUNCTION AND DEVELOPMENT Bergstrom DE 1 Bergstrom RA 1 Munroe RJ 2 Schimenti JC 2 Gagnon LH 1 Johnson KR 1 Heinzmann U 3 Stumm G 4 Paffenholz R 4 1 The Jackson Laboratory Bar Harbor United States 2 Cornell University Ithaca United States 3 GSF National Research Center for Environmental Health Neuherberg Germany 4 Ingenium Pharmaceuticals Martinsried Germany 73 HOLOPROSENCEPHALY AT DEL 13 SVEA36H Bogani D 1 Willoughby C 1 Mirza G 2 Davies J 1 Ragoussis I

    Original URL path: http://www.imgs.org/Archive/abstracts/2004abstracts/toc5.shtml (2016-02-17)
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  • 18th International Mouse Genome Conference (2004)
    B The Scripps Research Institute La Jolla United States 89 FINE MAPPING OF THE TMEVP3 LOCUS Bureau JF Levy Acobas F Levillayer F Brahic M Szatanik M Institut Pasteur Paris France 90 3D A NOVEL MUTATION THAT CONFERS DEFECTIVE SENSING BY TOLL LIKE RECEPTORS 3 7 AND 9 Tabeta K 1 Du X 1 Georgel P 1 Hoebe K 1 Goode J 1 Mann N 1 Mudd S 1 Sovath S 1 Shamel L 1 Crozat K 1 Csencsits L 2 Tarantino L 2 Cooke MP 2 Beutler B 1 1 The Scripps Research Institute La Jolla United States 2 The Genomics Institute of the Novartis Research Foundation San Diego United States 91 THE NONSENSE ALLELE OBLIVIOUS REVEALS A SENSOR OF DI ACYLGLYCERIDES ACTING IN CONJUNCTION WITH TLR2 AND TLR6 Hoebe K 1 Georgel P 1 Rutschmann S 1 Du X 1 Tabeta K 1 Mudd S 1 Sovath S 1 Shamel L 1 Hartung T 2 Zahringer U 3 Beutler B 1 1 The scripps Research Institue La Jolla United States 2 Department of Biochemical Pharmacology University of Konstanz Konstanz Germany 3 Research Center Borstel Leipniz center for Medicine and Bioscience Borstel Germany 92 SUSCEPTIBILITY OF INBRED MICE TO FATAL INFECTION BY MOUSE ADENOVIRUS TYPE 1 Spindler KR Welton AR University of Michigan Ann Arbor United States 93 DEVELOPMENT OF PATHOLOGY IN A J C57BL 6 AND BALB C MICE FOLLOWING TRYPANOSOMA CONGOLENSE INFECTION Mburu D 1 Naessens J 1 Noyes H 2 Kemp S 2 Gibson J 3 Iraqi F 1 1 International Livestock Research Institute ILRI Nairobi Kenya 2 University of Liverpool Liverpool United Kingdom 3 University of New England Armidale Australia 94 THE CAPACITY TO CONTROL OF ANEMIA DEVELOPMENT AND PARASITEMIA GROWTH IS UNDER DIFFERENT GENETIC MECHANISMS IN AFRICAN MURINE TRYPANOSOMOSIS Naessens J 1 Mburu D

    Original URL path: http://www.imgs.org/Archive/abstracts/2004abstracts/toc6.shtml (2016-02-17)
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  • 18th International Mouse Genome Conference (2004)
    TO EXPRESSION INFORMATION FOR THE LABORATORY MOUSE Begley DA Eppig JT Finger JH Hayamizu TF Hill DP Kadin JA McCright IJ Richardson JE Smith CM Ringwald M The Jackson Laboratory Bar Harbor United States 103 THE GENE ONTOLOGY CONSORTIUM BIO ONTOLOGIES FOR GENOME ANNOTATIONS Blake JA Gene Ontology Consortium The The Jackson Laboratory Bar Harbor United States 104 SNPLAD A SNP DISCOVERY PIPELINE FOR IDENTIFYING CANDIDATE SNP IN PUBLIC EST TRACE FILES Noyes HA Amigo Lechuga J Broadhead AM Hughes M Morton IG Rennie K Kemp SJ University of Liverpool Liverpool United Kingdom 105 INTEGRATING MOUSE SNPS INTO MGI PLANS PROGRESS AND PROTOTYPES Richardson JE Blake JA Bult CJ Eppig JT Kadin JA King BL Ringwald M The Jackson Laboratory Bar Harbor United States 106 HIGH THROUGHPUT YEAST TWO HYBRID STRATEGIES FOR PROTEOME WIDE PROTEIN PROTEIN INTERACTION MAPS Zhong J 1 Finley R 2 1 Current affiliation Laboratory of Genetics National Institute on Aging NIH Baltimore MD United States 2 Center for Molecular Medicine and Genetics Wayne State University Detroit MI United States 107 ASSEMBLING THE MOUSE GENOME WGS AND CLONE BASED METHODS Church DM 1 Baily JA 3 Eichler EE 2 Agarwala R 1 1 NIH NCBI Bethesda United States 2 University of Washington Seattle United States 3 Case Western Reserve University Medical School Cleveland United States 108 MOUSE GENOME RESOURCES AT NCBI Church DM Annotation Team NCBI NIH NCBI Bethesda United States 109 IN SILICO POSITIONAL CANDIDATE GENE ANALYSIS IN THE MOUSE NEW TOOLS FROM THE MOUSE GENOME INFORMATICS CONSORTIUM Bult CJ Ringwald M Blake JA Kadin JA Richardson JE Eppig JT Sequences and Maps Group MGI Phenotypes Group MGI Expression Group MGI Software Group MGI The Jackson Laboratory Bar Harbor United States 110 COMPLEX BIOLOGICAL SYSTEMS AND BIOINFORMATICS SOME NEW BIOINFORMATICS TOOLS AND APPROACHES Snoddy J GST

    Original URL path: http://www.imgs.org/Archive/abstracts/2004abstracts/toc7.shtml (2016-02-17)
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  • 18th International Mouse Genome Conference (2004)
    INFIDELITY AND INBRED MOUSE STRAINS Wiles MV Chu T Palmer JH The Jackson Laboratory Bar Harbor United States 117 FUNCTION OF RECQ DNA HELICASES BLM AND RECQL5 IN THE SUPPRESSION OF MITOTIC CROSSOVERS AND MAINTENANCE OF GENOMIC STABILITY Hu Y Barnes E Luo G Case Western Reserve University Cleveland United States 118 APOE GENOTYPE AND AMYLOID BETA METABOLISM IN A MOUSE MODEL OF ALZHEIMER S DISEASE Mann KM Lamb BT Department of Genetics Case Western Reserve University and University Hospitals of Cleveland Cleveland United States 119 THE HETEROZYGOUS DEAFWADDLER MOUSE IS A MODEL FOR AGE RELATED HEARING LOSS McCullough BJ Tempel BL University of Wasington Seattle United States 120 IL 15R a IS A NEGATIVE REGULATOR OF THE ACTIVATION OF CD4 T CELLS AND AUTOIMMUNITY Lee JM Hou MS Chung CY Chiang WW Yang ST Liou YH Liao NS Institute of Molecular Biology Academia Sinica Taipei Taiwan 121 SCREENING FOR LONGEVITY GENES IN MICE Johnson DK 1 Miller DR 1 Moustaid Moussa N 2 Goldowitz D 3 1 Life Sciences Division Oak Ridge National Laboratory Oak Ridge United States 2 Dept of Nutrition University of Tennessee Knoxville United States 3 Dept of Anatomy and Neurobiology University of Tennessee Health Sciences

    Original URL path: http://www.imgs.org/Archive/abstracts/2004abstracts/toc8.shtml (2016-02-17)
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  • 18th International Mouse Genome Conference (2004)
    M 1 Masuya H 1 Kaneda H 1 Kobayashi K 1 Suzuki T 1 Wada Y 1 Wakana S 1 Minowa O 1 Gondo Y 3 Shiroishi T 1 Noda T 1 1 Mouse Functional Genomics Research Group RIKEN GSC Tsukuba Japan 2 Radiation Biology and Medicine Hiroshima University Hiroshima Japan 3 Population and Quantitative Genomics Team RIKEN GSC Yokohama Japan 129 GENERATION OF GENETIC TOOLS FOR FUNCTIONAL ANALYSIS OF THE MOUSE CHROMOSOME 15 Chick WSH 1 Mentzer SE 2 Carpenter DA 2 Rinchik EM 1 You Y 2 1 The University of Tennessee Knoxville United States 2 Oak Ridge National Laboratory Oak Ridge United States 130 GENOME WIDE MUTATION DISCOVERY BY TGCE IN GENE DRIVEN APPROACH OF ENU MUTAGENESIS Sakuraba Y Sezutsu H Takahasi R Uchiyama M Tsuchihashi K Fujimoto N Ichikawa R Kaneko S Goda N Ikeda A Karashima Y Inoue M Kaneda H Minowa O Wakana S Noda T Shiroishi T Gondo Y RIKEN GSC Yokohama Japan 131 MOSTRACK INFORMATICS FOR LARGE SCALE MUTAGENESIS PROJECT Yang P Kuo Y Ho M Cheng C Lin M Lin W Kung J Mouse Mutagenesis Program Core Facility Taipei Taiwan 132 THE GNF ENU MUTAGENESIS SCREEN USING ENU MUTAGENESIS TO IDENTIFY GENES INVOLVED IN NEUROBIOLOGY Tarantino LM 1 Schwander M 2 Dong H 1 Hice R 1 Wiltshire T 1 Mueller U 2 1 Genomics Institute of the Novartis Research Foundation San Diego United States 2 The Scripps Research Institute La Jolla United States 133 CROSS SPECIES STUDY OF THE ODZ GENE FAMILY Zheng L Nakamura H Lossie A Jafar Nejad H Schulze K Bellen H Justice M Department of Molecular and Human Genetics Baylor College of Medicine Houston United States 134 BIOINFORMATICS PIPELINE FOR ENU MOUSE MUTAGENESIS Liu B Zhong J Tran N Fan M Justice M Baylor College of

    Original URL path: http://www.imgs.org/Archive/abstracts/2004abstracts/toc9.shtml (2016-02-17)
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  • 18th International Mouse Genome Conference (2004)
    Zeretzke SZ 1 Hrabé de Angelis MHdA 1 Tocchini Valentini GTV 2 Herault YH 3 Brown SB 4 Ährlund Richter LAR 5 Mallo MM 6 Thornton JT 7 1 GSF Research Center for Environment and Health Institute of Experimental Genetics Munich Germany 2 CNR Istituto di Biologia Cellulare Monterotondo Italy 3 CNRS Centre de Distribution de Typage et d Archivage animale Orleans France 4 MRC Mammalian Genetic Unit Harwell United Kingdom 5 Karolinska Institutet Unit for Embryology and Genetics Stockholm Sweden 6 FCG Instituto Gulbenkian de Ciencia Oeiras Portugal 7 EMBL EBI European Bioinformatics Institute Hinxton United Kingdom 156 AUTOMATED DNA PURIFICATION FROM MOUSE TAILS Mulrooney C Howe S Robinson J Oultram J Sayle J Tepnel Life Sciences Manchester United Kingdom 157 CHARACTERIZATION OF TWO NOVEL ENU INDUCED CIRCADIAN MUTANT LINES Godinho SIH Shaw Andrews L Clay J Bacon Y Nolan PM MRC Harwell United Kingdom 158 ENU MUTAGENESIS REVEALS A NEW ROLE FOR THE AF4 PROTEIN FAMILY IN NEURODEGENERATION Oliver PL Bitoun E Clark J Davies KE MRC Functional Genetics Unit Oxford United Kingdom 159 CRANIOFACIAL GENE DISCOVERY IN MICE Donahue LR Curtain M Giggey J Guido V Hurd J Davisson M The Jackson Laboratory Bar Harbor United States 160 IDENITIFICATION OF ENU GENERATED MUTANTS FOR ANXIETY AND ACTIVITY IN AN OPEN FIELD TEST Pletcher MT Grabowski L Wiltshire T Tarantino L The Genomics Institute of the Novartis Research Foundation San Diego United States 161 NEURAL CREST DEFICIT IN CRANIOFACIAL SKELETON PRECURSORS OF TS65DN MICE A MODEL FOR DOWN SYNDROME Roper RJ Reeves RH Johns Hopkins University School of Medicine Baltimore United States 162 ANALYSIS OF A NEW DOMINANT HAIRLOSS MUTANT MAPPING TO MOUSE CHROMOSOME 11 Weber JS 1 Rahajeng J 1 Kovar J 2 1 University of Nebraska Lincoln United States 2 LI COR BioSciences Lincoln United States 163 CORRECTION OF PATHOLOGICAL AGGRESSION IN THE FIERCE MOUSE BY HUMAN NUCLEAR RECEPTOR 2E1 Abrahams BS Kwok MCH Trinh E Budaghzadeh S Hossain SM Simpson EM University of British Columbia Vancouver Canada 164 SENSITIVITY OF STRIATAL PROJECTION NEURONS TO MITOCHONDRIAL DYSFUNCTION IN OMI DEFICIENT MND2 MICE Jones JM 1 Tallaksen Greene S 2 Albin RL 2 Meisler MH 1 1 University of Michigan Department of Human Genetics Ann Arbor United States 2 University of Michigan Department of Neurology Ann Arbor United States 165 CHARACTERIZATION OF NEW MICE MODELS OF MOTOR NEURON DISEASES Achilli F 1 Nolan P 2 Fisher EMC 1 1 Institute of Neurology London United Kingdom 2 MRC Mammalian Genetic Unit Harwell United Kingdom 166 FURTHER MAPPING OF THE MOUSE DEAFNESS MUTANT BRONX WALTZER Taylor A 1 Cheong MA 2 Bussoli TJ 2 Kelly A 2 Steel KP 1 1 Wellcome Trust Sanger Institute Cambridge United Kingdom 2 MRC Institute of Hearing Research Nottingham United Kingdom 167 NEW CANDIDATE GENES FOR WOBBLER EXPRESSION PROFILING AND MODIFIED PHENOTYPE Schmitt John T Drepper C Hahn P Mussmann A Ulbrich M Beckers J Jockusch H Univerity of Bielefeld Bielefeld Germany 168 A NOVEL MOUSE MUTATION HEMORRHAGIC HYDROCEPHALUS HHY MAPS TO CHROMOSOME

    Original URL path: http://www.imgs.org/Archive/abstracts/2004abstracts/toc10.shtml (2016-02-17)
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  • 18th International Mouse Genome Conference (2004)
    disease Advances in the manipulation of the mouse genome has led to the emergence of novel ways to explore basic biology and the development of relevant models of human disease Highlighted themes for the conference include the genetics of aging and infectious disease and advances in gene therapy using RNAi Epigenetics and comparative genomics are also spotlighted in the program Richard Palmiter a pioneer in the development of transgenic mouse technology and its application to the study of the role of genes in development and disease will give the Verne Chapman Memorial lecture Many people contributed to the organization of this meeting and we are grateful to the members of the Secretariat of the International Mammalian Genome Society for their contributions in planning the scientific presentations Darla Miller as usual has been invaluable in bringing this meeting to fruition And the excellent efforts of Katy Armstrong Emily Walton and Hayley Burton along with the rest of the staff at In Conference Edinburgh made our job in Seattle much easier and efficient Sandya Narayanswami was especially valuable in guiding our local and foundation fund raising efforts We would also like to give special thanks to Kris Carroll for creating the IMGC 2004 logo Sponsorship for this meeting comes from a variety of sources but primarily from the US National Institutes of Health the US Department of Energy and Mouse Newsletter Ltd These sources fund a number of student scholarships as well as the speaker travel In addition to these sources we have received contributions from a variety of pharmaceutical and publishing companies who are gratefully acknowledged This year we were particularly fortunate to receive funding from the Ellison Medical Foundation which is supporting two sessions the Genetics of Infectious Disease and Genome Instability and Aging These sessions correspond to the Ellison

    Original URL path: http://www.imgs.org/Archive/abstracts/2004abstracts/welcome.shtml (2016-02-17)
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