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  • Re: Nanotubes
    12 In Reply to Nanotubes posted by Scelestus I guess this is another shot at creating an immunobarrier as opposed to immunosuppression If it works and if funding agencies do not manage to keep it off the market then pig islets could be transplanted without toxic immunosuppression to restore normal blood glucose control to people whose own islets have been destroyed by autoimmunity Al Follow Ups Post a Followup Name

    Original URL path: http://islet.org/forum/messages/56091.htm (2016-04-29)
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  • Viacyte
    submit reviews input submit button default button default fusion button default ticket selector submit btn type submit border radius 0 webkit border radius 0 reading box background color FFFFFF isotope isotope item transition property top left opacity webkit transition property top left opacity moz transition property top left opacity ms transition property top left opacity o transition property top left opacity comment form input type submit fusion button fusion load more button ticket selector submit btn type submit font family PT Sans Arial Helvetica sans serif font weight 700 fusion image wrapper fusion rollover fusion rollover gallery before fusion image wrapper fusion rollover fusion rollover link before font size 15px margin left 7px line height 36px color ffffff searchform search table search field input height 33px searchform search table search button input type submit height 33px width 33px line height 33px fusion title size one h1 margin top 0 67em margin bottom 0 67em 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    Original URL path: http://islet.org/forum/messages/56089.htm (2016-04-29)
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  • New device
    life changing for those with type 1 diabetes 1 2589913 setPlaylistTmp playlist 0 http www ctvnews ca polopoly fs 1 2589823 1443701924 httpImage image jpg gen derivatives landscape 620 image jpg BEGIN CTVOmnitureTracking requiresDependency http esi2 ctv ca players mediaplayer builds ETS Universal includes Metrics js function Metrics VIDEOPLAYER NAME CTV News Video Player Story requiresDependency http player 9c9media com channels ctvnews web apiInterfaceOne js function END CTVOmnitureTracking Event binding Whenever a video starts highlight it in the story video player nav jQuery document unbind isDone onVideoStart bind isDone onVideoStart function event clipId clipTitle infoObjCategory navPageTurner clipId infoObjCategory highlightClip clipId www requiresDependency http static ctvnews ca bellmedia common js articlePlayerNavigation js function Populate video nav Initially load page 1 populatePlayerNav 1 setCurrClipPage 1 setCurrUserPage 1 Populate video nav pagination First page s index is 0 populatePagination 0 Highlight page 1 by default highlightCurrPageNum 1 jQuery document bind isDone onPlayerReady function setPlaylistTmp playlist 0 http www ctvnews ca polopoly fs 1 2589823 1443701924 httpImage image jpg gen derivatives landscape 620 image jpg gigya socialize showShareBarUI createArticleGigyaParams gigTitle gigURL gigDesc gigImg www whenRequired componentDiv http static ctvnews ca Angela Mulholland Staff writer AngeMulholland Published Thursday October 1 2015 9 29AM EDT Last Updated Thursday October 1 2015 12 56PM EDT An experimental new device currently being tested in humans could vastly change the lives of those with Type 1 diabetes potentially freeing them up from daily insulin injections and monitoring Type 1 or juvenile diabetes as it used to be called is the less common form of the disease that s often diagnosed in childhood In Type 1 the pancreas no longer produces adequate insulin so patients must rely on daily injections of the hormone to manage their blood sugar The promising new device now being studied is called the Encaptra drug delivery system Itâ s a capsule about the width of a credit card that is implanted under the skin near the pancreas Inside are stem cells that have been programmed to develop into pancreatic islet cells which are the cells that help regulate blood sugar The Juvenile Diabetes Research Foundation is helping to fund research into the device Dave Prowten the president of JDRF Canada says the cells are designed to mature once inside the body and begin producing insulin on their own â The hope is that this will provide people with an alternate source of insulin â he told CTVâ s Canada AM Thursday from Calgary Because Type 1 diabetes is an autoimmune disease in which the body mistakenly attacks and kills pancreatic cells the device is also designed to shield the cells from an autoimmune attack So far clinical testing in mice shows the device performs well with the stem cells continuously assessing blood glucose and then releasing the appropriate amount of insulin Now the device is being tested in humans The device was implanted into a single Canadian patient about a month ago and now researchers are watching to see how it performs Canadian country singer George Canyon who has had Type 1 diabetes since he was 14 says heâ s excited about this new research â This little device to me is the closest thing to a cure that Iâ ve ever seen â he told CTVâ s Canada AM while holding up the 4 centimetre long device Canyon says whatâ s frustrating and psychologically draining for diabetics like him is that their disease requires constant vigilance â We donâ t get a day off as a Type 1 diabetic Weâ re constantly testing constantly taking insulin â he said â This device hopefully could give me 10 to 12 months at a time of not really having diabetes being able to go a day without testing and taking insulinâ This is Disney World right here â The goal of the study currently underway is to evaluate the safety of the device and see if the body rejects it But at the same time researchers will be monitoring its effectiveness at replacing the pancreasâ lost insulin production Researchers hope that the device could remain implanted for at least a year and possibly longer before needing to be replaced Canyon says he welcomes any breakthrough that makes daily life easier for those with Type 1 diabetes and heâ s hopeful this device could be what heâ s been waiting for â This is going to change the lives of over 300 000 Type 1 diabetics in Canada â he said â Itâ s incredibly exciting It could make such a difference â Related Stories Brown fat transplant reverses type 1 diabetes in mice Big study to test insulin pills as Type 1 diabetes prevention Photos Michael Scott a ViaCyte vice president holds the VC 01 device that holds stem cells that will mature to make insulin K C Alfred Country singer George Canyon and Dave Prowten president of JDRF Canada var paragraphs jQuery articleBody children p 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  • JDCA report on JDRF
    operations fundraising education and salaries a significant gain compared to 36 in 2008 12 of total annual income was spent on cure research based on a review of all of the 387 projects funded by the JDRF during 2014 see opening graphic above Cure research at 12 is a very small percentage of the JDRF s overall resource utilization which seems unaligned with a central mission of finding a cure This is the third annual analysis of JDRF s funding of research The main purpose in reviewing and sharing this data is to help ensure that T1D donor and community priorities are being addressed The JDRF merits such extensive review and study because in our view there is no other organization that is as well positioned to bring about a major T1D cure breakthrough While some may think these findings unsettling our intent is to be constructive not destructive and to spur a powerful organization to even higher levels of performance In preparing the report the JDCA team reviewed financial data for each of past ten years and reviewed all 387 projects funded by JDRF in fiscal year 2014 see appendix C for macro grant trends A similar analysis was

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  • BCG trials
    url https wprp zemanta com static window wp rp wp ajax url http asweetlife org wp admin admin ajax php window wp rp plugin version 3 5 4 window wp rp post id 38241 window wp rp num rel posts 5 window wp rp thumbnails false window wp rp post title Faustman 27s Research on BCG Vaccine for Reversal of Type 1 Diabetes Continues window wp rp post tags window wp rp promoted content false vvqbox display block max width 100 visibility visible important margin 10px auto vvqbox img max width 100 height 100 vvqbox object max width 100 googletag cmd push function googletag display div gpt ad 1364861669187 0 Secondary menu Skip to primary content Skip to secondary content Search for Subscribe About Us Contributors Contact The Diabetes Magazine Home Features Diabetes Type 1 Diabetes Type 2 Diabetes Type 2 Diabetes Treatments Gestational Diabetes Tips Recipes Blogs News Books A Sweet Life Features Diabetes Cure Faustman s Research on BCG Vaccine for Reversal of Type 1 Diabetes Continues Faustman s Research on BCG Vaccine for Reversal of Type 1 Diabetes Continues Alex Oâ Meara September 16 2015 Category Research Tags Diabetes Cure 0 0 0 0 The phase I trial of a once controversial clinical trial testing the effects on type one diabetes of a 94 year old drug used to combat tuberculosis was so successful that in June of this year the FDA approved the research to expand into a second phase of the trial â The data went further than we expected â Dr Denise Faustman Director of the Immunobiology Laboratory at the Massachusetts General Hospital and an Associate Professor of Medicine at Harvard Medical School says about the first phase of the trial which was concluded in 2012 â It was supposed to be a safety trial to see biomarker changes but the results we produced went beyond that â The results of the test on Bacillus Calmette Guà rin or BCG did in fact show it was safe to use on type 1 diabetics But because of the widespread use of the generic drug for so many years that was expected But the small doses of BCG administered to as two vaccines in three subjects followed for 2 years compared to 97 placebo and untreated reference subjects revealed the specific death of so called â badâ T cells that attack and kill insulin producing islet cells Additionally the subjects who had diabetes for 15 years or more showed a â transient increase in restoration of pancreatic insulin secretion after BCG vaccination â according to Faustman and the peer reviewed published data For phase II 150 subjects with type one diabetes for 15 or even 20 years who do not suffer from any diabetic complications such as neuropathy retinopathy and others will be tested for five years to determine the dose and frequency of dosages required to potentially reverse type 1 diabetes Faustman said The subjects aged 18 to 60 must have low but still detectable

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  • Re: BCG trials
    2015 09 16 In Reply to BCG trials posted by DanT One could be tempted to self administer couldn t one Al Follow Ups Re BCG trials Edward 13 09 09 2015 09 17 0 Post a Followup Name E

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  • Re: BCG trials
    2015 09 17 In Reply to Re BCG trials posted by Al Gordon Al let us know the results Ed Follow Ups Re BCG trials Al Gordon 13 39 45 2015 09 17 0 Post a Followup Name E Mail

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  • Re: BCG trials
    BCG trials posted by Edward I will do that Ed For me a sample size of one will be statistically significant Now where does one get BCG Al Follow Ups Re BCG trials Frank Cz 22 22 32 2015 09

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