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  • Re: Viacyte
    on 14 20 47 2016 02 04 In Reply to Re Viacyte posted by Jeff Thanks Jeff Follow Ups Re Viacyte Al Gordon 17 53 46 2016 02 04 0 Post a Followup Name E Mail Optional Subject Comments Link

    Original URL path: http://islet.org/forum/messages/56158.htm (2016-04-29)
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  • Re: Viacyte
    allowing oxygen glucose and insulin to pass freely So why not test the immunobarrier with pig islets that we know will work in humans and will test the barrier s effectiveness at preventing an immune attack while still allowing adequate oxygenation of all cells within the barrier If that works we have an near infinite supply of islet cells and a dramatic demonstration of Viacyte s technology Thousands of people

    Original URL path: http://islet.org/forum/messages/56159.htm (2016-04-29)
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  • Re: Viacyte
    around the device because it won t integrate into the body That is why I ve always been a fan of Sernova s technology I agree with Al both these companies need to start using porcine islets before stem cell derived islets Al do you know if the stem cells do go cancerous are they contained in the pouch or can they slip out and spread Jeff Follow Ups Re

    Original URL path: http://islet.org/forum/messages/56160.htm (2016-04-29)
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  • Re: Viacyte
    and let me preface this by saying I m not a medical person Regarding the scar tissue concern how long would that take It seems like there is often a mention of needing to replace this type of device periodically What if it needed to be replaced every say 6 12 24 months or whatever If the process was sufficiently non invasive and insurance could find it cost effective to

    Original URL path: http://islet.org/forum/messages/56163.htm (2016-04-29)
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  • Re: Viacyte
    the pouches of Viacyte vs Sernova Specifically you mention that the Viacyte pouch will not integrate with blood vessels scar tissue issues etc but I assume you suspect the Sernova pouch will integrate and not be victim of scar tissue You may very well be right about this but it seems odd that Viacyte and J J would keep moving forward with a device destined for failure Thanks for your

    Original URL path: http://islet.org/forum/messages/56162.htm (2016-04-29)
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  • Re: Viacyte
    enough oxygen and nutrients to survive Oxygen starving cells may survive for a while but the conditions are not ideal Sernova s device forms the microvessel rich tissue chambers into which the therapeutic cells are placed Sernova has already shown that islets can survive and function in their device They become fully vascularized even in humans and sit in a tissue matrix These are key features for survival and function

    Original URL path: http://islet.org/forum/messages/56164.htm (2016-04-29)
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  • Re: Viacyte
    cause cancer and after thousands of years of humans handling pigs and millions of opportunities for living pig cells entering the human body through wounds there has never been a single case recorded of a zoonotic infection from pig cells So pig islets work to restore normal blood glucose control in humans with no demonstrated risks and Viacyte claims to have an immunobarrier that is biocompatible and can protect living

    Original URL path: http://islet.org/forum/messages/56161.htm (2016-04-29)
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  • Re: Viacyte
    Al Either ViaCyte or Sernova could put LCT s diabacell product into their device Sernova mentions that it s a 15 min outpatient procedure to install a device Even if it lasts a year a time before getting re filled it d be worth it Making money is a bigger driver for many companies rather than helping patients That is the unfortunate truth of the world we live in Follow

    Original URL path: http://islet.org/forum/messages/56165.htm (2016-04-29)
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