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  • Assessment Of The Value Of Adding LH Activity During The Late Stages Of Follicular Maturation In ICSI Cycles | Sharkawy | Evidence Based Women's Health Journal
    Home About Log In Register Search Current Archives Announcements Editorial Team Videos CME Contact Us Home Vol 1 No 2 2011 Sharkawy The PDF file you selected should load here if your Web browser has a PDF reader plug in installed for example a recent version of Adobe Acrobat Reader Alternatively you can also download the PDF file directly to your computer from where it can be opened using a PDF reader To download the PDF click the Download link below If you would like more information about how to print save and work with PDFs Highwire Press provides a helpful Frequently Asked Questions about PDFs Download this PDF file Fullscreen Fullscreen Off Comments on this article Parents refused loan what can I do by 12 petterrjx petterrjx petterrjxBP 2012 01 04 cheap authentic uggs GDST by 222 asicutesli asicutesli denimweiny KO 2012 12 19 Just one fashion to wasting get an overnight payday loan by 12 akzeniust akzeniust akzeniustazer 2013 01 12 Technique to ensure you are obtaining an overnight payday loan by 12 akzeniust akzeniust akzeniustazer 2013 01 12 Reliable organization is almost always to search out critiques to target other fast cash advance firms by 12 akzeniust

    Original URL path: http://pub.moriat.org/index.php/EBWHJ/article/view/78/70 (2016-05-01)
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  • Assessment Of The Value Of Adding LH Activity During The Late Stages Of Follicular Maturation In ICSI Cycles | Sharkawy | Evidence Based Women's Health Journal
    8 1 5 36 0 126 Cause of infertility Male factor 140 53 128 61 0 115 Unexplained 122 47 83 39 BMI 25 77 2 57 26 25 2 41 0 083 AFC 9 13 2 55 8 44 2 25 0 207 The clinical pregnancy rate in group B the study group was significantly higher than that of group A the control group 40 versus 29 p There was no significant difference between the 2 groups regarding the total number of embryos the number of good embryos transferred number of fair embryos transferred the number of freeze embryos and the number of cancelled cycles These data are shown in table 2 There was one case of ectopic pregnancy in the control group Table 2 Characteristics of the cycles Variable Group A Group B p value Number of cancelled cycles 25 263 13 211 0 183 Inadequate response 20 11 0 295 Hyperresponse 5 2 0 469 Total number of stimulation days 12 9 1 96 14 3 2 19 P 0 01 Total number of ampoules 41 63 9 81 56 97 15 P 0 01 Total number of embryos 3 28 1 02 3 1 0 96 0 147 Number of good embryos transferred 1 89 1 26 2 08 1 29 0 218 Number of fair embryos 1 03 1 28 0 73 1 02 0 095 Freeze embryos 1 19 1 46 1 0 1 23 0 261 Clinical pregnancy per transfer 70 238 29 79 192 40 0 011 Discussion Based on scientific and basic data denoting that late stages of follicular maturation during ovarian stimulation need more LH stimulation compared to earlier stages 3 4 we planned for this study We used highly purified FSH preparation for ovarian stimulation in the control group In the study group we replaced highly purified FSH with HP HMG when the leading follicle is 10 12 mm Our primary aim was to compare the outcome in terms of clinical pregnancy rate According to our results the clinical pregnancy rate was significantly higher after adding a preparation with higher LH stimulation 40 Vs 29 p Moreover it was found that endometrial maturation is disturbed in women with low endogenous LH but can be rescued by mid cycle stimulation of LH receptor 18 The number of stimulation days and the total number of ampoules were significantly higher in the group received HP HMG This finding is supported by a study of Kumbak and Kahraman 19 who found better consumption and stimulation duration with rFSH compared with rFSH plus rLH However another study suggested that ovulation induction with LH activity containing menotropins is associated with shorter treatment duration and lower menotropin consumption 20 The different findings among studies regarding this point can be related to different preparations used wide dosage variation and heterogenous patient population Indeed there is controversy regarding the value of LH and its effect on outcome of IVF cycles A systematic review concluded that among women with normal ovulation or WHO type II oligo anovulation low endogenous LH levels during ovarian stimulation for IVF using GnRH analogues are not associated with a decreased probability of ongoing pregnancy beyond 12 weeks 21 Several systematic reviews compared recombinant gonadotrophin with urinary gonadotrophins HMG purified FSH highly purified FSH for ovarian hyperstimulation in IVF and ICSI cycles and these reported conflicting results Each of these reviews used different inclusion and exclusion criteria for trials However the most recent one which is a Cochrane review showed no evidence of a statistically significant difference in live birth rate between recombinant FSH and urinary gonadotrophins 28 trials 7339 couples odds ratio 0 97 95 CI 0 87 to 1 08 22 This deleterious effect of LH on oocyte quality needs further evaluation It has been suggested that LH per se does not have a negative impact on normal granulosa cells The hypothetical deleterious effects of high LH concentrations are observed only in PCOS patients and appear to be related to concomitant hyperinsulinemia 23 Another advantage of LH stimulation is its ability to reduce the occurrence of small pre ovulatory follicles This finding combined with its role to support growth and function of larger follicles independently of FSH further extends the potential advantages of sequential FSH HP hMG This may have potential implications in reduction of ovarian hyperstimulation cases 24 Available information suggests that LH stimulation can be used to improve and optimize FSH stimulation for COS The lack of positive results reported by some studies may be related to the use of inadequate or excessive amounts of LH stimulation or other confounding factors such as variable gonadotropin dosages variable preparations of gonadotropins or the pituitary desensitization regimen employed 25 The present study has clear limitations being quasirandomised could not eliminate all sources of bias and this has a negative impact on background characteristics in terms of tendency to higher BMI in control group which could may have affected the duration of stimulations and number of ampoules However this study stressed on the value of adding LH activity in the last few days of ovarian stimulation Further trials should concentrate on the individuals who could benefit from LH supplementation the best time during stimulation to shift into a preparation with higher LH stimulation In conclusion our data suggest that adding LH activity in later stages of follicular maturation may improve clinical pregnancy rates References Alviggi C Clarizia R Mollo A Ranieri A De Placido G 2011 Who needs LH in ovarian stimulation Reprod Biomed Online 22 Suppl 1 33 41 pmid 21575848 Google Scholar Shima K Kitayama S Nakano R 1987 Gonadotropin binding sites in human ovarian follicles and corpora lutea during the menstrual cycle Obstet Gynecol Obstet Gynecol 69 800 806 Google Scholar Hillier S G 1994 Current concepts of the roles of follicle stimulating hormone and luteinizing hormone in folliculogenesis Hum Reprod 9 188 191 Google Scholar Howles C M 2000 Role of LH and FSH in ovarian function Molecular and Cellular

    Original URL path: http://pub.moriat.org/index.php/EBWHJ/article/view/78/77 (2016-05-01)
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  • Does Hydration shorten the duration of Labour? | Rezk | Evidence Based Women's Health Journal
    Rezk Does Hydration shorten the duration of Labour Ahmed Rezk Abstract Objectives the objective of this study is to assess the effect of intravenous infused fluid on progress of labour Patients and Methods this is a randomized controlled trial conducted at the department of Obstetrics and Gynaecology at Banha University and Al Mahla General Hospital in which 150 pregnant women in active phase of labour were randomly allocated into three groups Group A received 250 ml hour Ringer s Solution Group B received 125 ml hour Ringer s Solution and Group C control group Patients were followed up until delivery and all their data were recorded on the partogram Results the results of our study reflected that group A has more uterine contractions than group B and group C and this difference was statistically significant In addition to that group A showed faster descent of the fetal head than group B and group C and this difference was significant statistically Moreover women in group A showed a longer mean SD duration of contraction than that of group B and group C 38 44 1 7 36 32 1 1 35 15 0 07 respectively Besides that women in group A

    Original URL path: http://pub.moriat.org/index.php/EBWHJ/article/view/52 (2016-05-01)
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  • Early diagnosis of Neonatal Sepsis In Obstetric Ward: The Role of 16S rRNA Gene Sequence Analysis | El-Hawary | Evidence Based Women's Health Journal
    References Rahman S Hameed A Roghani M T Ullah Z 2002 in Peshawar Pakistan Arch Dis Child Fetal Neonatal Ed 2002 Jul 87 1 F52 4 PubMed PMID 12091293 PubMed Central PMCID PMC1721434 pmid 12091293 Google Scholar Osrin D Vergnano S Costello A 2004 Serious bacterial infections in newborn infants in developing countries Current Opinion in Infectious Diseases 17 3 217 224 Retrieved from http content wkhealth com linkback openurl sid WKPTLP landingpage an 00001432 200406000 00008 doi 10 1097 00001432 200406000 00008 Google Scholar Ohlin A Bäckman A Björkqvist M Mölling P Jurstrand M Schollin J 2008 Real time PCR of the 16S rRNA gene in the diagnosis of neonatal bacteraemia Acta Paediatrica 97 10 1376 1380 Retrieved from http doi wiley com 10 1111 j 1651 2227 2008 00924 x doi 10 1111 j 1651 2227 2008 00924 x Google Scholar Griffin M P Moorman J R 2001 Toward the Early Diagnosis of Neonatal Sepsis and Sepsis Like Illness Using Novel Heart Rate Analysis Pediatrics 107 1 97 104 Retrieved from http pediatrics aappublications org cgi doi 10 1542 peds 107 1 97 doi 10 1542 peds 107 1 97 Google Scholar Kellogg J A Ferrentino F L Goodstein MH Liss J Shapiro S L Bankert DA age Pediatr Infect Dis J 1997 Frequency of low level bacteremia in infants from birth to two months of 16 381 385 Google Scholar Jordan J A Durso M B bacteremia J Clin Microbiol 2000 Comparison of 16S rRNA gene PCR and BACTEC 9240 for detection of neonatal 38 2574 2578 Google Scholar Brozanski B S Jones J G Krohn M J Jordan J A 2006 Use of polymerase chain reaction as a diagnostic tool for neonatal sepsis can result in a decrease in use of antibiotics and total neonatal intensive care unit length of stay J Perinatol 26 11 688 692 Retrieved from http www nature com doifinder 10 1038 sj jp 7211597 doi 10 1038 sj jp 7211597 Google Scholar Jordan J A 2005 Dueso MB Real time polymerase chain reaction for detecting bacterial DAN directly from blood of neonates being evaluated for sepsis J Mol Diagn 7 5 575 581 Retrieved from http linkinghub elsevier com retrieve pii S1525157810605909 doi 10 1016 S1525 1578 10 60590 9 Google Scholar Jordan J A Durso M B Butchko A R Jones K G 2006 Brozanski BS Evaluating the near term infant for early onset sepsis progress and challenges to consider with 16rDNA polymerase chain reaction testing J Mol Diagn 8 3 357 363 Retrieved from http linkinghub elsevier com retrieve pii S1525157810603145 doi 10 2353 jmoldx 2006 050138 Google Scholar Qian Q Tang Y W Kolbert C P Torgerson C A Hughes J G Vetter E A Persing D H 3578 Direct identification of bacteria from positive blood cultures by amplification and sequencing of the 16S rRNA gene evaluation of BACTEC 9240 instrument true positive and false positive results J Clin Microbiol 2001 Oct 39 10 PubMed Central PMCID 3578

    Original URL path: http://pub.moriat.org/index.php/EBWHJ/article/view/75 (2016-05-01)
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  • Early diagnosis of Neonatal Sepsis In Obstetric Ward: The Role of 16S rRNA Gene Sequence Analysis | El-Hawary | Evidence Based Women's Health Journal
    Index terms Full Text Browse By Issue By Author By Title Other Journals Font Size Home About Log In Register Search Current Archives Announcements Editorial Team Videos CME Contact Us Home Vol 1 No 2 2011 El Hawary The PDF file you selected should load here if your Web browser has a PDF reader plug in installed for example a recent version of Adobe Acrobat Reader Alternatively you can also

    Original URL path: http://pub.moriat.org/index.php/EBWHJ/article/view/75/63 (2016-05-01)
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  • Editorial | Abdelmoniem | Evidence Based Women's Health Journal
    Journals Font Size Home About Log In Register Search Current Archives Announcements Editorial Team Videos CME Contact Us Home Vol 1 No 2 2011 Abdelmoniem Editorial Tamer Abdelmoniem Abstract Dear reader It is pleasure to introduce the second issue of Evidence Based Women s Health Journal in its new look As we promised our readers that we will keep on publishing a high quality research articles and providing them with the best available evidence in this issue we have modified the style of the first page in the articles to contain a box which states the current knowledge about the published topic and what is added by these articles Therefore we will be able to supply our readers with the different point of views as well as highlighting the value of the published work Moreover I would like to declare that all our articles have been investigated for plagiarism at the eTBLAST website that is an online search engine for text similarity We are proud to announce that the maximum ratio of similarity in our published articles was 0 19 whereas the cut off value for considering a plagiarism was 0 56 The year 2012 will carry a surprise to

    Original URL path: http://pub.moriat.org/index.php/EBWHJ/article/view/71 (2016-05-01)
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  • Editorial | Abdelmoniem | Evidence Based Women's Health Journal
    By Issue By Author By Title Other Journals Font Size Home About Log In Register Search Current Archives Announcements Editorial Team Videos CME Contact Us Home Vol 1 No 2 2011 Abdelmoniem Dear reader It is pleasure to introduce the second issue of Evidence Based Women s Health Journal in its new look As we promised our readers that we will keep on publishing a high quality research articles and providing them with the best available evidence in this issue we have modified the style of the first page in the articles to contain a box which states the current knowledge about the published topic and what is added by these articles Therefore we will be able to supply our readers with the different point of views as well as highlighting the value of the published work Moreover I would like to declare that all our articles have been investigated for plagiarism at the eTBLAST website that is an online search engine for text similarity We are proud to announce that the maximum ratio of similarity in our published articles was 0 19 whereas the cut off value for considering a plagiarism was 0 56 The year 2012 will carry

    Original URL path: http://pub.moriat.org/index.php/EBWHJ/article/view/71/75 (2016-05-01)
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  • Fertility Preservation By Identifying Women With SLE At High Risk Of Ovarian Toxicity On Exposure To Cyclophosphamide By Determination Of CYP2C19 Genotype | Alaetebi | Evidence Based Women's Health Journal
    the wild type of CYP2C19 was 25 72 compared to 45 71 with variant homozygous type of CYP2C19 while those with variant heterozygous type were 28 57 The percentage of patients having ovarian failure with the wild type of CYP2C19 was 85 71 compared to 0 with variant homozygous type of CYP2C19 while those with variant heterozygous type were 14 29 The sensitivity of the wild type as a predictor for ovarian toxicity is 85 7 while the specificity is 25 7 Conclusion it is possible to predict which patient with SLE could be of high risk of ovarian toxicity on exposure to cyclophosphamide by determination of CYP2C19 genotype Keywords SLE Fertility preservation Cyclophosphamide Ovarian toxicity References Masellis M Basile V S Ozdemir V Meltzer H Y Macciardi F M Kennedy J L 2000 Pharmacogenetics of antipsychotic treatment lessons learned from clozapine Biol Psychiatry 47 3 252 66 Retrieved from http linkinghub elsevier com retrieve pii S000632239900298X doi 10 1016 S0006 3223 99 00298 X Google Scholar Appenzeller S Blatyta P F Costallat L T 2008 Ovarian failure in SLE patients using pulse cyclophosphamide comparison of different regimes Rheumatol Int 28 6 567 71 Retrieved from http www springerlink com index 10 1007 s00296 007 0478 3 doi 10 1007 s00296 007 0478 3 Google Scholar Vang R Medeiros L J Warnke R A Higgins J P Deavers M T 2001 Ovarian non Hodgkin s lymphoma a clinicopathologic study of eight primary cases Mod Pathol 14 11 1093 9 Retrieved from http www nature com doifinder 10 1038 modpathol 3880442 doi 10 1038 modpathol 3880442 Google Scholar Singh G Saxena N Aggarwal A Misra R 2007 Cytochrome P450 polymorphism as a predictor of ovarian toxicity to pulse cyclophosphamide in systemic lupus erythematosus J Rheumatol 34 4 731 3 Google Scholar

    Original URL path: http://pub.moriat.org/index.php/EBWHJ/article/view/76 (2016-05-01)
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