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  • Pretreatment SUV of the metastatic neck lymph nodes predicts neck control and survival in patients with stage IV oro/hypopharyngeal cancers | Abd El-Hafez | Egyptian Journal of Nuclear Medicine Specialists
    El Hafez Y Tzu Chen H Khalil H Moustafa Abstract Purpose To investigate the prognostic significance of standardized uptake value SUV of metastatic neck lymph nodes measured on FDG PET CT in patients with stage IVoro hypopharyngeal cancers treated by definitive chemoradiotherapy CCRT Methods Retrospective analysis of 65 patients with clinically N stage IV SCC of the oro hypopharyngeal squamous cell carcinoma SCC who underwent FDG PET CT scans for primary staging Follow up continued till death or at least 24 months from the start of treatment The primary study endpoint was neck control NC The log rank test and Cox proportional hazard analysis were used to identify significant prognostic factors Results The 3 year NC rate was 53 In univariate analysis N3 status and nodal SUV 9 8 were significantly associated with reduced NC In multivariable analyses nodal SUV retained its independent prognostic significance as a predictor of NC Lymph node stage was an independent predictor of disease specific survival DSS A prognostic scoring system was constructed as follows score 0 N0 N2 and nodal SUV 9 8 score 1 N3 or nodal SUV 9 8 and score 2 N3 and nodal SUV 9 8 Patients with a score

    Original URL path: http://pub.moriat.org/index.php/EJNMS/article/view/126 (2016-05-01)
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  • Septal flattening in rest Tc-99m tetrofosmin gated SPECT is a significant predictor of pulmonary hypertension | Salem | Egyptian Journal of Nuclear Medicine Specialists
    study aimed at documentation of septal flattening during rest gated SPECT imaging with echocardiographic confirmation of pulmonary hypertension or right ventricular overload Methods The study included 68patients 35 males 33 females mean age 49 11 years with echocardiographic proven pulmonary hypertension All patients were subjected to conventional echocardiography and rest gated SPECT perfusion scanning following injection of 555 MBq Tc 99m tetrofosmin using triple head general purpose large field scintillation gamma camera Results The study population divided into 2 groups group A patients showed septal flattening in gated SPECT 56 patients 82 and group B patients did not show septal flattening 12 patients 18 Septal flattening in gated SPECT significantly correlated with pulmonary artery pressure 85 7 16 4 mmHg for group A compared to 50 12 5 mmHg for group B P 0 001 pulmonary artery diameter 37 0 6 mm for group A compared to 21 0 4 mm for group B P 0 02 LV diastolic volume 156 4 24 ml for group A compared to 111 12 5 ml for group B P 0 004 and RV tracer uptake There was no significant correlation between septal flattening and septal thickness 0 92 0 16 cm for

    Original URL path: http://pub.moriat.org/index.php/EJNMS/article/view/128 (2016-05-01)
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  • 99mTc-HMPAO in Brain SPECT Imaging; Feasibility of Ultra-Utilization of the Cold kit with higher 99mTc activities - A Chromatographic Study | Bayomy | Egyptian Journal of Nuclear Medicine Specialists
    widely used as an efficient brain perfusion agent due to the ability of the primary 99mTc HMPAO complex to penetrate the intact blood brain barrier BBB which is believed to be attributed to its lipophilic property Hung 1994 The primary lipophilic 99mTc HMPAO complex is inherently unstable and rapidly converts to a secondary less lipophilic complex Retention in the brain results from the inability of the secondary complex to cross the blood brain barrier Ponto 1990 Thus we have here one more impurity ligand in addition to the 2 other persisting impurities which are the free and hydrolyzed reduced technetium The radiochemical purity of the 99mTc HMPAO preparation could be recognized by using a combination of three thin layer chromatographic TLC systems Tikofsky 1993 HMPAO commercial kits are one of the most expensive materials in nuclear medicine in addition to that the added Tc 99m activities proposed by the commercial venders can be enough to perform only 2 patient studies per vial which is not cost effective especially in developing countries that obstacles depending on brain SPECT as a routine imaging protocol To overcome this there are two postulated solutions one is to collect a larger number of patients per

    Original URL path: http://pub.moriat.org/index.php/EJNMS/article/view/129 (2016-05-01)
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  • Contrast Evaluation for a Dual Head SPECT System with Different Energy Peaking-Drift | Saad | Egyptian Journal of Nuclear Medicine Specialists
    total photon energy absorbed by the detector Physically peaked detectors will center the energy window on the photo peak of selected isotope Aim of the study Our aim is to evaluate the effect of energy peak drifting for both imaging heads on the image contrast in SPECT Materials and methods Using a dual head gamma camera the SPECT phantom with its inserts was scanned using a fixed acquisition protocol and image reconstruction parameters but with changing the energy peak window adjustment which was operated for both heads at different values starting from 120 KeV up to 160 KeV with incremental step of 5 KeV and the window width was adjusted to be 15 as used in the clinical applications Results Our results shows a fluctuation in the image contrast as there was a gradual increase in the contrast value from 120 KeV setting up to 140 KeV by 31 and also there was a gradual decrease in the contrast value from 140 KeV setting up to 160 KeV setting by 15 The clinical verification for these results was done on cardiac patient who underwent a cardiac scan twice with the normal gamma camera peak setting and then with off peak

    Original URL path: http://pub.moriat.org/index.php/EJNMS/article/view/130 (2016-05-01)
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  • Thallium 201 scanning can diagnose multiple recurrences in forearm implanted parathyroid tissue post total parathyroidectomy | Wagih | Egyptian Journal of Nuclear Medicine Specialists
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    Original URL path: http://pub.moriat.org/index.php/EJNMS/article/view/131 (2016-05-01)
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