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  • Research trio outlines ways nanodiamonds are being used to treat cancer
    and nucleic acid delivery demonstrated substantial improvements over unmodified drug administration Recent preclinical studies have shown that combination nanotherapies composed of either multiple classes of nanomaterials or a single nanoplatform functionalized with several therapeutic agents can image and treat tumors with improved efficacy over single compound delivery Among the many promising nanomaterials that are being developed nanodiamonds have received increasing attention because of the unique chemical mechanical properties on their faceted surfaces More recently nanodiamond based drug delivery has been included in the rational and systematic design of optimal therapeutic combinations using an implicitly de risked drug development platform technology termed Phenotypic Personalized Medicine Drug Development PPM DD The application of PPM DD to rapidly identify globally optimized drug combinations successfully addressed a pervasive challenge confronting all aspects of drug development both nano and non nano This review will examine various nanomaterials and the use of PPM DD to optimize the efficacy and safety of current and future cancer treatment How this platform can accelerate combinatorial nanomedicine and the broader pharmaceutical industry toward unprecedented clinical impact will also be discussed Journal reference Science Advances 532 shares feedback to editors 2015 Phys org Tweet Favorites Email Print PDF Featured Last comments Popular Detection of gravitational waves would open new window on universe Feb 10 2016 58 Gravitational waves detected 100 years after Einstein s prediction Feb 11 2016 144 GPS tracking down to the centimeter Feb 11 2016 10 A metal that behaves like water Feb 11 2016 2 Physicists create first photonic Maxwell s demon 14 hours ago 3 more Phys org on facebook Relevant PhysicsForums posts The great basic question of science on origin of life 1 hour ago How to create microscope videos 2 hours ago Fly feeling 11 hours ago Why do you get pressure drop in central circulation 11 hours ago Novel Idea on the Origin of Life 12 hours ago Opening the blood brain barrier with collapsing bubbles 21 hours ago More from Biology and Medical Related Stories Tiny diamonds to boost treatment of chemoresistant leukemia September 11 2013 By binding multiple molecules of a common leukemia drug with nanodiamonds scientists from the National University of Singapore NUS and University of California Los Angeles UCLA managed to boost the delivery of the drug New system uses nanodiamonds to deliver chemotherapy drugs directly to brain tumors September 12 2013 Phys org Researchers at UCLA s Jonsson Comprehensive Cancer Center have developed an innovative drug delivery system in which tiny particles called nanodiamonds are used to carry chemotherapy drugs directly into brain Nanodiamond tech lights new path in medical diagnostics August 11 2014 Earlier this month TechCrunch featured a look at a company that wants to make a difference in finding cancer before it spreads using nanodiamond based technology The idea is that nanodiamonds can detect molecular abnormalities An unlikely use for diamonds October 27 2014 Tiny diamonds are providing scientists with new possibilities for accurate measurements of processes inside living cells with potential to improve drug

    Original URL path: http://phys.org/news/2015-08-trio-outlines-ways-nanodiamonds-cancer.html (2016-02-13)
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  • Nanoparticle delivery maximizes drug defense against bioterrorism agent
    site of infection Horwitz added that freely flowing drugs are metabolized and excreted from the moment they are administered whereas nanoparticles protect drug molecules from metabolism and excretion until after their release in the target cells making nanotherapeutics potentially very potent The study compared the efficacy of freely injected moxifloxacin with that delivered by the controlled release nanoparticles In mice given a highly lethal dose of Francisella tularensis the nanoparticle delivered moxifloxacin caused few side effects and was more effective at reducing the number of bacteria in the lungs than a dose of freely injected moxifloxacin two to four times greater The nanoparticle delivery system has the potential to maximize antibiotic effectiveness and reduce side effects in other infectious diseases including tuberculosis Q fever and Legionnaires disease Explore further New triggered release mechanism could improve drug delivery More information Zilu Li et al Mesoporous Silica Nanoparticles with pH Sensitive Nanovalves for Delivery of Moxifloxacin Provide Improved Treatment of Lethal Pneumonic Tularemia ACS Nano 2015 DOI 10 1021 acsnano 5b04306 Journal reference ACS Nano Provided by University of California Los Angeles 65 shares feedback to editors Tweet Favorites Email Print PDF Featured Last comments Popular Detection of gravitational waves would open new window on universe Feb 10 2016 58 Gravitational waves detected 100 years after Einstein s prediction Feb 11 2016 144 GPS tracking down to the centimeter Feb 11 2016 10 A metal that behaves like water Feb 11 2016 2 Physicists create first photonic Maxwell s demon 14 hours ago 3 more Phys org on facebook Relevant PhysicsForums posts The great basic question of science on origin of life 1 hour ago How to create microscope videos 2 hours ago Fly feeling 11 hours ago Why do you get pressure drop in central circulation 11 hours ago Novel Idea on the Origin of Life 12 hours ago Opening the blood brain barrier with collapsing bubbles 21 hours ago More from Biology and Medical Related Stories New triggered release mechanism could improve drug delivery January 16 2015 More efficient medical treatments could be developed thanks to a new method for triggering the rearrangement of chemical particles Nanoparticles target and kill cancer stem cells that drive tumor growth June 10 2015 Many cancer patients survive treatment only to have a recurrence within a few years Recurrences and tumor spreading are likely due to cancer stem cells that can be tough to kill with conventional cancer drugs But now researchers Scientists use nanoparticles to shut down mechanism that drives cancer growth July 3 2015 When scientists develop cancer therapies they target the features that make the disease deadly tumor growth metastasis recurrence and drug resistance In epithelial cancers cancers of the breast ovaries prostate Targeted drug delivery with these nanoparticles can make medicines more effective September 16 2015 Nanoparticles disguised as human platelets could greatly enhance the healing power of drug treatments for cardiovascular disease and systemic bacterial infections These platelet mimicking nanoparticles developed by engineers Recommended for you Scientists create ultrathin

    Original URL path: http://phys.org/news/2015-11-nanoparticle-delivery-maximizes-drug-defense.html (2016-02-13)
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  • Nanotech-based sensor developed to measure microRNAs in blood, speed cancer detection
    for many patients it is symptom free for years or even a decade or more by which time it has spread to other organs when surgical removal is no longer possible and therapeutic options are limited said Korc For example diagnosis of pancreatic cancer at an early stage of the disease followed by surgical removal is associated with a 40 percent five year survival Diagnosis of metastatic pancreatic cancer by contrast is associated with life expectancy that is often only a year or less The beauty of the sensor designed by Dr Sardar is its ability to accurately detect mild increases in microRNA levels which could allow for early cancer diagnosis Korc added Over the past decade studies have shown that microRNAs play important roles in cancer and other diseases such as diabetes and cardiovascular disorders The new IUPUI nanotechnology based sensor can detect changes in any of these microRNAs The sensor is a small glass chip that contains triangular shaped gold nanoparticles called nanoprisms After dipping it in a sample of blood or another body fluid the scientist measures the change in the nanoprism s optical property to determine the levels of specific microRNAs Using gold nanoprisms may sound expensive but it isn t because these particles are so very tiny Sardar said It s a rather cheap technique because it uses nanotechnology and needs very little gold 250 worth of gold makes 4 000 sensors Four thousand sensors allow you to do at least 4 000 tests The low cost makes this technique ideal for use anywhere including in low resource environments in this country and around the world More information Gayatri K Joshi et al Label Free Nanoplasmonic Based Short Noncoding RNA Sensing at Attomolar Concentrations Allows for Quantitative and Highly Specific Assay of MicroRNA 10b in Biological Fluids and Circulating Exosomes ACS Nano 2015 DOI 10 1021 acsnano 5b04527 Journal reference ACS Nano Provided by Indiana University Purdue University Indianapolis School of Science 474 shares feedback to editors Tweet Favorites Email Print PDF Featured Last comments Popular Detection of gravitational waves would open new window on universe Feb 10 2016 58 Gravitational waves detected 100 years after Einstein s prediction Feb 11 2016 144 GPS tracking down to the centimeter Feb 11 2016 10 A metal that behaves like water Feb 11 2016 2 Physicists create first photonic Maxwell s demon 14 hours ago 3 more Phys org on facebook Relevant PhysicsForums posts The great basic question of science on origin of life 1 hour ago How to create microscope videos 2 hours ago Fly feeling 11 hours ago Why do you get pressure drop in central circulation 11 hours ago Novel Idea on the Origin of Life 12 hours ago Opening the blood brain barrier with collapsing bubbles 21 hours ago More from Biology and Medical Related Stories Recommended for you Scientists create ultrathin semiconductor heterostructures for new technologies February 12 2016 Heterostructures formed by different three dimensional semiconductors form the foundation for modern electronic

    Original URL path: http://phys.org/news/2015-11-nanotech-based-sensor-micrornas-blood-cancer.html (2016-02-13)
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  • Researchers propose rapid Ebola test using nanotechnology
    the sick while they await their fate Conventional methods of detection are good but slow and should be performed at Biosafety Standard Level 3 laboratories which are expensive to maintain and require skilled personnel Kaushik says Marty who was recently appointed to the Presidential Advisory Council on Combating Antibiotic Resistant Bacteria also noted that the lack of appropriate safety work stations and effective selective rapid diagnostics methodologies will continue to be significant challenges in the fight against EBOV But a cost effective rapid sensitive and selective sensor that can detect Ebola at point of care could literally be lifesaving It is important to devise more rapid more sensitive but also more specific and appropriate diagnostic assays for Ebola because there are grave social economic and medical even lethal consequences to a misdiagnosis Marty says This requires that only diagnostics tests that have undergone independent comprehensive assessment of quality safety and performance be used in confirming the diagnosis of infection with Ebola virus While this new nano technology is extremely promising we must be very careful to assure that a definitive diagnosis is given only if the specificity is extremely high a criteria that becomes even more important as the incidence and prevalence of Ebola disease continues to decrease This nanotechnology is currently likely to be a good screening test but it should still be backed up with nucleic acid testing using technologies such as polymerase chain reaction PCR Kaushik s lab has been working on miniaturized sensing technology and integrating that into devices that are capable of detecting virus levels for quite some time Combining the collaborative strengths of a biologist nanotechnologist and engineers to develop smart compartments to integrate point of care POC Ebola sensing devices in a BSL 4 environment should be the aim of future research approach in this area We believe that if we explore this option the length of time it will take to detect the Ebola virus will be reduced to 40 minutes instead of multiple hours Kaushik says That s time well spent More information Ajeet Kaushik et al Towards detection and diagnosis of Ebola virus disease at point of care Biosensors and Bioelectronics 2016 DOI 10 1016 j bios 2015 08 040 Journal reference Biosensors and Bioelectronics Provided by Florida International University 61 shares feedback to editors Tweet Favorites Email Print PDF Featured Last comments Popular Detection of gravitational waves would open new window on universe Feb 10 2016 58 Gravitational waves detected 100 years after Einstein s prediction Feb 11 2016 144 GPS tracking down to the centimeter Feb 11 2016 10 A metal that behaves like water Feb 11 2016 2 Physicists create first photonic Maxwell s demon 14 hours ago 3 more Phys org on facebook Relevant PhysicsForums posts The great basic question of science on origin of life 1 hour ago How to create microscope videos 2 hours ago Fly feeling 11 hours ago Why do you get pressure drop in central circulation 11 hours ago Novel Idea

    Original URL path: http://phys.org/news/2015-11-rapid-ebola-nanotechnology.html (2016-02-13)
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  • Bio & Medicine News - Nanobiology News, Nanomedicine News, Nanotech News, Nanotechnology News
    shell of a Hepatitis E virus to carry vaccines or drugs into the body The technique has been tested in rodents as a way to target breast cancer and is available Feb 03 2016 in Bio Medicine 81 0 Novel nanoparticle made of common mineral may help keep tumor growth at bay Engineers at Washington University in St Louis found a way to keep a cancerous tumor from growing by using nanoparticles of the main ingredient in common antacid tablets Feb 02 2016 in Bio Medicine 726 0 Too few proteins prompt nanoparticles to clump Blood serum proteins have been observed combining one to one with gold nanoparticles and prompting them to aggregate scientists at Rice University reported Jan 28 2016 in Bio Medicine 31 0 Fighting disease with tiny targeted crystalline drug mules Development of effective new treatments for cancer dementia Parkinson s disease and other brain conditions is becoming possible from breakthrough discoveries being made in nanotechnology Jan 27 2016 in Bio Medicine 52 0 Scientists synthesize nanoparticles that can deliver tumor suppressors to damaged livers UT Southwestern Medical Center chemists have successfully used synthetic nanoparticles to deliver tumor suppressing therapies to diseased livers with cancer an important hurdle scientists have been struggling to conquer Jan 25 2016 in Bio Medicine 1422 0 Microscopic drug depots boost efficacy against tumors in animal model Biomedical engineering researchers have developed a technique for creating microscopic depots for trapping drugs inside cancer tumors In an animal model these drug depots were 10 times more effective at shrinking tumors Jan 25 2016 in Bio Medicine 39 0 A step closer to artificial cell division by blowing bubbles By blowing extremely small bubbles researchers from the Kavli Institute of Nanoscience at Delft University of Technology TU Delft have found an efficient way of

    Original URL path: http://phys.org/nanotech-news/bio-medicine/sort/date/all/?utm_source=sort-date&utm_medium=link&utm_campaign=tmpl-main-l (2016-02-13)
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  • End to end 5G for super, superfast mobile
    SK Telecom introduces world s fist LTE A network More information Lai J Jiang L Lei M Abdollahpouri A and Fang W 2015 Software defined cellular networking a practical path towards 5G Int J Communication Networks and Distributed Systems Vol 14 No 1 pp 89 105 Provided by Inderscience Publishers 0 shares feedback to editors Tweet Favorites Email Print PDF Featured Last comments Popular Detection of gravitational waves would open new window on universe Feb 10 2016 58 Gravitational waves detected 100 years after Einstein s prediction Feb 11 2016 144 GPS tracking down to the centimeter Feb 11 2016 10 A metal that behaves like water Feb 11 2016 2 Physicists create first photonic Maxwell s demon 14 hours ago 3 more Phys org on facebook Relevant PhysicsForums posts Looking for the right DC motor 30 minutes ago Support angle for steel rack 1 hour ago How high the tower 4 hours ago Engineering project ideas for an engineering club in my school Feb 11 2016 Looking to build a backyard windmill Feb 11 2016 Electronic component type what would do this Feb 11 2016 More from General Engineering Related Stories SK Telecom introduces world s fist LTE A network June 26 2013 South Korea s SK Telecom announced Wednesday the launch of a new generation mobile network that offers speeds twice that of its existing long term evolution LTE network and 10 times that of 3G services EU South Korea join forces for faster mobile service June 16 2014 The European Union on Monday said it was teaming up with South Korea to develop a next generation 5G wireless service quick enough to download full length movies to a smartphone in seconds Cutting congestion on the data network highway September 12 2014 Perhaps no other consumer driven technology has made such incredible advances in such a relatively short space of time as the mobile phone Today s smartphones are used to stream videos access social media and perform all 5G mobile networks will support an internet that s so good you can feel it September 30 2014 With the roll out of 4G mobile internet not even yet complete it might seem early to consider starting work on the design of the next fifth generation 5G mobile networks The truth is that telecoms systems are so complex 5G is NOT 4G 1 November 5 2014 Recently Spaniards had to re tune all television sets as a result of the introduction of 4G mobile networks Their data transmission speed 10 times higher than the 3rd generation s required a release of the frequency band Recommended for you AT T testing superfast 5G mobile network February 12 2016 AT T announced plans Friday to begin testing a superfast fifth generation or 5G mobile network with speeds up to 100 times faster than the most rapid existing connections Picasa being shuttered in shift to Google Photos February 12 2016 Google on Friday said it will be shuttering Picasa to shift its

    Original URL path: http://phys.org/news/2014-11-5g-super-superfast-mobile.html (2016-02-13)
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  • AT&T testing superfast 5G mobile network
    would begin the field tests later this year in collaboration with US semiconductor giant Intel and Swedish networking group Ericsson Global telecom operators are readying for 5G deployment in 2020 but some carriers appear to be moving ahead of schedule The new 5G networks could open up a range of services by delivering data at much faster speeds enabling services such as remote surgery or driverless cars and allowing customers to experience video and virtual reality with ease New experiences like virtual reality self driving cars robotics smart cities and more are about to test networks like never before said AT T chief strategy officer John Donovan These technologies will be immersive pervasive and responsive to customers 5G will help make them a reality AT T said it would begin lab tests of 5G starting in the second quarter and outdoor tests in Austin Texas before the end of the year The trials will help guide our 5G standards contributions and set the stage for widespread commercial and mobile availability once technology standards for 5G are established AT T said We expect 5G to deliver speeds 10 100 times faster than today s average 4G LTE connections US rival carrier

    Original URL path: http://phys.org/print374501338.html (2016-02-13)
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  • Phone firms and the quest for the 5G Holy Grail
    have fallen behind Asia and the United States in the deployment of 4G The Samsung Galaxy S6 is presented during the 2015 Mobile World Congress in Barcelona on March 1 2015 In Barcelona on Tuesday Guenther Oettinger the EU digital economy commissioner said the bloc wanted to sign agreements with Japan China and the United States to cooperate on 5G research It has already signed such an accord with South Korea With 5G Europe has a great opportunity to reinvent its telecom industrial landscape Oettinger told an audience at the congress on Tuesday He presented the EU s vision for 5G which forecasts that seven trillion smart objects could one day be connected to the Internet In Asia South Korea alone has invested 1 6 billion aiming to commercialise 5G technology by 2020 according to the GSMA Japan aims to have 5G services available in time for the 2020 Olympic Games in Tokyo Among companies Samsung LG Huawei all the big players are trying to test certain types of equipment that they think will be 5G Kevin Curran a computer sciences specialist at the University of Ulster told AFP But what equipment we re going to use in six or seven years time in modern times it s very hard to predict Explore further S Korea to spend 1 5 bn on 5G movie in a second service 311 shares feedback to editors 2015 AFP Tweet Favorites Email Print PDF Featured Last comments Popular Detection of gravitational waves would open new window on universe Feb 10 2016 58 Gravitational waves detected 100 years after Einstein s prediction Feb 11 2016 144 GPS tracking down to the centimeter Feb 11 2016 10 A metal that behaves like water Feb 11 2016 2 Physicists create first photonic Maxwell s demon 14 hours ago 3 more Phys org on facebook Relevant PhysicsForums posts Looking for the right DC motor 30 minutes ago Support angle for steel rack 1 hour ago How high the tower 4 hours ago Engineering project ideas for an engineering club in my school Feb 11 2016 Looking to build a backyard windmill Feb 11 2016 Electronic component type what would do this Feb 11 2016 More from General Engineering Related Stories S Korea to spend 1 5 bn on 5G movie in a second service January 22 2014 South Korea already one of the most wired countries on earth Wednesday announced a 1 6 trillion won 1 5 billion plan to roll out a next generation 5G wireless service quick enough to download full length films in a second One second movie downloads on next mobile network February 23 2014 When the next super fast mobile network launches in 2020 you will be able to download a high definition movie in one second flat EU South Korea join forces for faster mobile service June 16 2014 The European Union on Monday said it was teaming up with South Korea to develop a next generation 5G wireless service quick enough

    Original URL path: http://phys.org/news/2015-03-firms-quest-5g-holy-grail.html (2016-02-13)
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