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  • Locations
    Videos Safety Store at Rady Children s Rethink Your Drink Injury Prevention Growing Up Columns Locations Main Campus Satellite Locations Emergency Urgent Care Programs Services Pulmonary Respiratory Medicine Locations Rady Children s Specialists Pulmonary Respiratory Medicine Locations Pulmonary Respiratory Medicine Team Conditions Treated Services Patient and Parent Education Research and Clinical Trials Fellowship Resources Locations Locations Pulmonary Respiratory Medicine Outpatient Clinics Rady Children s Hospital San Diego Map it 8110

    Original URL path: http://www.rchsd.org/programs-services/pulmonary-respiratory-medicine/locations/ (2015-03-26)
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  • Joshua: Meeting the Challenge
    at times For years Joshua has had a chronic cough a daily reminder for his mother Lynette that they must be constantly vigilant to manage his disease He used to cough a lot at night even in his sleep said Lynette It just rattles your heart Vigilance and football go hand in hand The family made a deal if Joshua follows his entire CF regimen every day without fail he could play football For those who can t imagine a 10 year old even making his bed every day consider the bar Joshua has to reach While CF is a manageable condition keeping it under control is far from easy Because the disease impairs the body s ability to distribute digestive enzymes Joshua must take supplements which come in very large capsules he takes six pills with each meal plus another three with snacks He must also take inhaled antibiotics to fight off the lung infections so common in CF patients But the real challenge is controlling the mucus in his lungs He uses a bronchodilator and inhales an enzyme preparation to help liquefy it He wears a special vest 20 minutes twice a day which connects to a machine that shakes his entire chest to loosen thick mucus Timing the treatments adds another layer of complexity Joshua uses an iPad alarm to keep him on track In addition he must also monitor his breathing and avoid dehydration To make matters even more complicated Joshua also has asthma But none of that is holding him back Mark Pian M D who specializes in pulmonary respiratory medicine at Rady Children s Hospital San Diego directs the Rady Children s University of California San Diego Cystic Fibrosis Center and is a professor of pediatrics at UC San Diego has been impressed by how Josh and his family handle his CF The treatments are very invasive in terms of quality of life Dr Pian said This disease is like a depth charge going off in the middle of a family It s a very serious chronic disease and its treatment requires a serious sustained effort Dr Pian also conducts CF research with the goal of discovering new treatments And Joshua even at his young age knows how important this is Very few young children understand why we want them involved in research but Joshua gets it Dr Pian said He s okay with getting his blood drawn because he wants to help others with CF Thanks to participation by CF patients in clinical research studies a new medication to treat the disease was approved by the Food and Drug Administration earlier this year Since March Joshua has been taking the drug called ivacaftor Kalydeco which treats the underlying causes of CF rather than the symptoms CF is caused by mutations in the CFTR protein which must travel to the cell surface to function In most CF patients the cells quality control mechanisms eliminate the defective protein before it gets anywhere near the surface

    Original URL path: http://www.rchsd.org/about-us/patient-stories/stories-2012/joshua-meeting-the-challenge/ (2015-03-26)
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  • Mountain High: Genetic Adaptation for High Altitudes Identified
    conditions at such high altitudes present a challenge for survival and these geographically distinct populations have adapted to cope with hypoxia or low levels of oxygen in the blood Interestingly many humans living at high elevations particularly in the Andes mountain region of South America are maladapted and suffer with CMS The disease is characterized by an array of neurologic symptoms including headache fatigue sleepiness and depression Often people with CMS suffer from strokes or heart attacks in early adulthood because of increased blood viscosity resistance to blood flow that can result in decreased oxygen delivery to organs and tissues Past studies of various populations show that CMS is common in Andeans occasionally found in Tibetans and absent from Ethiopians living on the East African high altitude plateau Therefore the researchers dissected the genetic mechanisms underlying high altitude adaptation by comparing genetic variation between Peruvian individuals from the Andes region with CMS and adapted subjects without CMS using whole genome sequencing They identified two genes ANP32D and SENP1 with significantly increased expression in the CMS individuals when compared to the non CMS individuals and hypothesized that down regulating these genes could be beneficial in coping with hypoxia While a number of published articles have described an association between certain genes and the ability for humans to withstand low oxygen at high levels it was very hard to be sure if the association was causal said principal investigator Haddad The researchers therefore looked at genetic orthologs corresponding gene sequences from another species in this case the fruit fly to assess the impact of observed genetic changes on function under conditions of hypoxia We found that flies with these genes down regulated had a remarkably enhanced survival rate under hypoxia said Haddad According to the scientists their findings have important implications not

    Original URL path: http://www.rchsd.org/about-us/newsroom/press-releases/mountain-high-genetic-adaptation-for-high-altitudes-identified/ (2015-03-26)
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  • Team
    Library Ask Your Nurse Videos Safety Store at Rady Children s Rethink Your Drink Injury Prevention Growing Up Columns Locations Main Campus Satellite Locations Emergency Urgent Care Programs Services Radiology Team Radiology Team Radiology Team Bone Densitometry DXA Computed Tomography CT EOS Orthopedic Imaging Magnetic Resonance Imaging MRI Locations Team Christopher Dory M D Staff Radiologist Jerry D Dwek M D Staff Radiologist Darryl K Evora M D Staff Radiologist

    Original URL path: http://www.rchsd.org/programs-services/radiology/team/ (2015-03-26)
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  • Bone Densitometry (DXA)
    Patient Stories Research Get Involved Events Publications Health Safety Health Library Ask Your Nurse Videos Safety Store at Rady Children s Rethink Your Drink Injury Prevention Growing Up Columns Locations Main Campus Satellite Locations Emergency Urgent Care Programs Services Radiology Bone Densitometry DXA Radiology Bone Densitometry DXA Radiology Team Bone Densitometry DXA Computed Tomography CT EOS Orthopedic Imaging Magnetic Resonance Imaging MRI Locations Bone Densitometry DXA Dual energy X ray absorptiometry DXA is a special X ray procedure that determines the strength of bones Doctors use this test to help prevent fractures Other means of assessing bone strength are also available but DXA is currently the most accurate method and uses the lowest amount of radiation for a pediatric bone scan In children DXA is most often performed on the spine hips or the entire body It is a painless non invasive procedure there are no injections or medications involved Your child s doctor may order a DXA scan if your child Has a recurrent or low trauma fracture Has chronic inflammatory disease Has hypogonadism Is immobilized Has a blood disorder Is on long term systemic glucocorticoid therapy Has osteogenesis imperfecta The test may also be used to monitor treatment

    Original URL path: http://www.rchsd.org/programs-services/radiology/bone-densitometry-dxa/ (2015-03-26)
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  • Computed Tomography (CT)
    CT Radiology Team Bone Densitometry DXA Computed Tomography CT EOS Orthopedic Imaging Magnetic Resonance Imaging MRI Locations Computed Tomography CT 64 Slice LightSpeed CT Scanner The 64 Slice LightSpeed CT Scanner can scan the entire body in less than five seconds If you ve ever tried to keep a child completely still especially if he s sick or scared you can imagine the challenges faced by the Radiology Department Now some of those challenges are gone forever replaced by equipment that is not only fast but amazing in its diagnostic capabilities The General Electric 64 Slice LightSpeed CT Scanner is unbelievably fast taking 64 slices or pictures every 1 3 of a second and can complete an entire body scan in less than five seconds a process that used to take five minutes This reduces and sometimes eliminates the need for sedation for most patients and dramatically reduces radiation exposure In the case of heart exams the new machine can often eliminate the need for invasive catheterizations through the arteries and into the heart chambers Instead physicians get a comprehensive tour literally in a heartbeat And speed is only the beginning The images can be reformatted almost instantly into 3

    Original URL path: http://www.rchsd.org/programs-services/radiology/ct-scan/ (2015-03-26)
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  • Magnetic Resonance Imaging (MRI)
    Care Programs Services Radiology Magnetic Resonance Imaging MRI Radiology Magnetic Resonance Imaging MRI Radiology Team Bone Densitometry DXA Computed Tomography CT EOS Orthopedic Imaging Magnetic Resonance Imaging MRI Locations Radiology MRI Center Acute Care Pavilion Lower Level 220 3010 Children s Way San Diego CA 92123 858 939 4550 858 636 2455 Magnetic Resonance Imaging MRI A kid friendly state of the art magnetic resonance imaging MRI machine is housed at Sharp and Children s MRI Center inside our Acute Care Pavilion The GE Discovery MR450 featuring the CinemaVision system enables kids to watch a movie or listen to music during an MRI exam Children who are able to hold still during the scan will be offered video goggles and headphones Getting an MRI can be a stressful experience that often requires young patients to be sedated Studies have shown that entertainment during an MRI exam can soothe anxiety and minimize claustrophobia leading to faster and better exams The non sedation option is generally for patients 5 years of age and older who fit the screening criteria Rady Children s Hospital San Diego is the only hospital in San Diego with this innovative technology To make the process even more

    Original URL path: http://www.rchsd.org/programs-services/radiology/magnetic-resonance-imaging-mri/ (2015-03-26)
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  • Locations
    MyChart About Us Who We Are Newsroom Patient Stories Research Get Involved Events Publications Health Safety Health Library Ask Your Nurse Videos Safety Store at Rady Children s Rethink Your Drink Injury Prevention Growing Up Columns Locations Main Campus Satellite Locations Emergency Urgent Care Programs Services Radiology Locations Radiology Locations Radiology Team Bone Densitometry DXA Computed Tomography CT EOS Orthopedic Imaging Magnetic Resonance Imaging MRI Locations Locations Rady Children s

    Original URL path: http://www.rchsd.org/programs-services/radiology/locations/ (2015-03-26)
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