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  • Brain circuitry outside the synaptic cleft | Philosophical Transactions of the Royal Society B: Biological Sciences
    networking of the brain It has also emerged that extracellular matrix ECM structures that enwrap central neuronal circuits can generate molecular signals that affect both neuronal and glial activity Thus it appears that the mechanism of information processing in the brain which has hitherto been associated almost exclusively with synaptic connections could also involve signalling outside the synaptic cleft In this theme issue research teams including leading experts on astroglia neuron communication and on ECM signalling report their recent findings share their views and discuss future conceptual advances in the field Potential implications for drug development and new therapeutic targets with regards to some common neurological conditions are discussed throughout the issue Read Read all articles from this issue online The Introduction is FREE to access Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Buy This issue is now available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions Anniversary issue with free commentaries archive material videos and blogs Browse by subject behaviour biochemistry bioengineering bioinformatics biomaterials biomechanics biophysics biotechnology cellular biology cognition computational biology developmental biology ecology environmental science evolution genetics genomics health and disease and epidemiology immunology microbiology molecular biology neuroscience

    Original URL path: http://rstb.royalsocietypublishing.org/content/brain-circuitry-outside-synaptic-cleft (2016-02-09)
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  • Complex network theory and the brain | Philosophical Transactions of the Royal Society B: Biological Sciences
    of the world s leading experts in contemporary brain network analysis by graph theory The contributions are focused on three big questions that seem important at this stage in the scientific evolution of the field How does the topology of a brain network relate to its physical embedding in anatomical space and its biological costs How does brain network topology constrain brain dynamics and function And what seem likely to be important future methodological developments in the application of graph theory to analysis of brain networks Clearer understanding of the principles of brain network organization is fundamental to understanding many aspects of cognitive function brain development and clinical brain disorders We hope this issue provides a forward looking window on this fast moving field and captures some of the excitement of recent progress in applying the concepts of graph theory to measuring and modeling the complexity of brain networks Read an interview with Guest Editor David Papo about the issue Read Read all articles from this issue online The Introduction is FREE to access Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Buy This issue is now available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350

    Original URL path: http://rstb.royalsocietypublishing.org/content/complex-network-theory-and-brain (2016-02-09)
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  • Epigenetic information-processing mechanisms in the brain | Philosophical Transactions of the Royal Society B: Biological Sciences
    DNA sequence Within the past decade their discovery has exploded into a major development in the biological sciences This is especially true with regard to the brain MicroRNAs protein transcription factors and extracellular vesicles called exosomes which shuttle these molecular signaling agents between neurons play a significant role in practically every aspect of brain function which includes the modulation of information processing mechanisms Furthermore these remarkable advances throw new light on the etiology and sequelae of maladies such as schizophrenia bipolar disorder autism and epilepsy as well as recovery from traumatic brain injury This theme issue presents a broad and timely overview of some of the most promising areas of neuroepigenetic research by leaders in their respective fields Read Read all articles from this issue online The Introduction is FREE to access Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Buy This issue is now available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions Anniversary issue with free commentaries archive material videos and blogs Browse by subject behaviour biochemistry bioengineering bioinformatics biomaterials biomechanics biophysics biotechnology cellular biology cognition computational biology developmental biology ecology environmental science evolution genetics genomics health and disease and

    Original URL path: http://rstb.royalsocietypublishing.org/content/epigenetic-information-processing-mechanisms-brain (2016-02-09)
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  • Language as a multimodal phenomenon: implications for language learning, processing and evolution | Philosophical Transactions of the Royal Society B: Biological Sciences
    has been studied considering speech or written text in isolation and focusing mainly on English and other related languages with very similar properties However we seldom communicate just using language by itself face to face communication includes meaningful information conveyed by the tone of voice facial expressions and movement of the hands head and body Moreover the arbitrary nature of linguistic symbols becomes less certain with a wider scope across the world s languages including spoken languages with many more sound symbolic forms and especially sign languages for which visual resemblance between language and things in the world is far more evident This theme issue discusses how taking a broader multimodal approach to language seeing language as part of a broader system of human communication may change the way we think about the nature of language how it is learned how it is used and how it may have developed in the first place Read Read all articles from this issue online The Introduction is FREE to access Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Buy This issue is now available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions Anniversary issue

    Original URL path: http://rstb.royalsocietypublishing.org/content/language-multimodal-phenomenon-implications-language-learning-processing-and-evolution (2016-02-09)
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  • Mirror neurons: fundamental discoveries, theoretical perspectives and clinical implications | Philosophical Transactions of the Royal Society B: Biological Sciences
    neurons The mirror mechanism is present in many cortical areas and brain centres of birds monkeys and humans with functions ranging from song production to the organisation of goal directed motor acts to emotional processes Despite a growing number of empirical investigations on mirror neurons several questions remain to be clarified about their emergence and functions This theme issue presents state of the art research in contemporary mirror mechanism studies Based on recent new findings it sheds light on the basic mechanisms anatomical substrates human monkey differences emergence during ontogeny principal functions and psychopathologies related to impairment in these systems The contributions in this issue dissect these topics address controversial issues and provide a framework to stimulate new research directions Read Read all articles from this issue online The Introduction is FREE to access Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Buy This issue is available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions Anniversary issue with free commentaries archive material videos and blogs Browse by subject behaviour biochemistry bioengineering bioinformatics biomaterials biomechanics biophysics biotechnology cellular biology cognition computational biology developmental biology ecology environmental science evolution genetics genomics health and disease

    Original URL path: http://rstb.royalsocietypublishing.org/content/mirror-neurons-fundamental-discoveries-theoretical-perspectives-and-clinical-implications (2016-02-09)
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  • Understanding perceptual awareness and its neural basis | Philosophical Transactions of the Royal Society B: Biological Sciences
    is a major scientific challenge of our times and perceptual awareness is an integral part of it This theme issue provides a timely focus on crucial insights from leading scientists on perceptual awareness and its neural basis The issue refers to key research questions and findings in perceptual awareness research and aims to be a catalyst for further research by bringing together the state of the art in this field It builds bridges between empirical and theoretical lines of investigation and proposes new directions for the study of multisensory awareness and the role of the states of the body therein Read Read all articles from this issue online The Introduction is FREE to access Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Buy This issue is now available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions Anniversary issue with free commentaries archive material videos and blogs Browse by subject behaviour biochemistry bioengineering bioinformatics biomaterials biomechanics biophysics biotechnology cellular biology cognition computational biology developmental biology ecology environmental science evolution genetics genomics health and disease and epidemiology immunology microbiology molecular biology neuroscience palaeontology physiology plant science structural biology synthetic biology systems biology taxonomy and

    Original URL path: http://rstb.royalsocietypublishing.org/content/understanding-perceptual-awareness-and-its-neural-basis (2016-02-09)
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  • Timing in neurobiological processes: from genes to behaviour | Philosophical Transactions of the Royal Society B: Biological Sciences
    molecular and cellular biology genomics and many other omics promote instead a new challenge into the investigation of brain mechanisms to capture the dynamics of processes that change systematically as a function of time Although many mechanisms within the organism rely on well defined timed processes there is limited cross talk among disciplines that investigate timing at different levels and on different time scales For this reason it has become necessary to promote a cross disciplinary investigation with the goal of understanding temporal dynamics within the brain and how these timed processes ultimately control and modulate behaviour and cognition The papers in this special issue address specific questions about timing at the genetic epigenetic cellular network behavioural and computational levels Read Read all articles from this issue online Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Buy This issue is now available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions Anniversary issue with free commentaries archive material videos and blogs Browse by subject behaviour biochemistry bioengineering bioinformatics biomaterials biomechanics biophysics biotechnology cellular biology cognition computational biology developmental biology ecology environmental science evolution genetics genomics health and disease and epidemiology immunology microbiology molecular

    Original URL path: http://rstb.royalsocietypublishing.org/content/timing-neurobiological-processes-genes-behaviour (2016-02-09)
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  • Space in the brain: cells, circuits, codes and cognition | Philosophical Transactions of the Royal Society B: Biological Sciences
    for lasting memories This Theme Issue illustrates this exceptionally integrative branch of neuroscience in which we join the dots from molecules to cells to complex behaviour and human cognition It brings together world leading experts in this area to integrate advances in optogenetics virtual reality inducible transgenics neuroimaging and computational neuroscience to define the neural mechanisms of navigation with implications extending to behavioural genetics robotics and medicine This Theme Issue accompanies a Royal Society Theo Murphy Meeting held in May 2013 Details of the meeting can be found here Guest Editor John O Keefe University College London and contributing authors Edvard Moser and May Britt Moser Norwegian University of Science and Technology have recently been awarded the Nobel Prize in Physiology or Medicine for discoveries that have illuminated how the brain calculates location and navigation Read Read all the articles in this issue online Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Listen Audio recordings from the meeting can be found here Access by clicking the button next to the speaker s name Watch An interview with guest editors Tom Hartley and Colin Lever Buy This issue is available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating

    Original URL path: http://rstb.royalsocietypublishing.org/content/space-brain-cells-circuits-codes-and-cognition (2016-02-09)
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