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  • Language in developmental and acquired disorders: converging evidence for models of language representation in the brain | Philosophical Transactions of the Royal Society B: Biological Sciences
    surprisingly little interaction between research on developmental disorders and those acquired after neurological injury In this issue we bring together experts from these different domains to discover shared insights into how language is acquired and how it is organised in the brain We find that on the one hand language can be divided into highly specialised processing stages that deal with specific components such as identifying speech sounds or applying grammatical rules and that problems with these processes can be found in both children and adults On the other hand it is evident that language depends heavily on interactions with more basic processes of attention and perception Our understanding of acquired language disorders in adults is increasingly informed by new insights about how language is initially learned This issue is based on a Discussion Meeting held at The Royal Society 10 11 June 2013 More information and the speaker list can be found here Read Read all articles from this issue online The Introduction is FREE to access Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Listen Audio recordings from the discussion meeting can be found here Access by clicking the button next to the speaker s name Buy This issue is available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B

    Original URL path: http://rstb.royalsocietypublishing.org/content/language-developmental-and-acquired-disorders-converging-evidence-models-language (2016-02-09)
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  • Synaptic plasticity in health and disease | Philosophical Transactions of the Royal Society B: Biological Sciences
    synaptic plasticity contribute to a wide range of neurological and cognitive disorders Contributions are a mixture of original research and review papers and brings together leading world experts in the field of synaptic plasticity Details of the meeting can be found here Read Read all articles from this issue online The Introduction is FREE to access Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Listen Audio recordings from the discussion meeting can be found here Access by clicking the button next to the speaker s name Video from the meeting Together with other forms of synaptic plasticity long term potentiation LTP is widely believed to provide the cellular mechanism underlying learning and memory The Royal Society recently held a discussion meeting to celebrate the 40 year anniversary of the discovery of LTP by Terje Lømo and Tim Bliss in 1973 In this video we speak to some of the organisers and speakers at the meeting about their meeting highlights the state of the research field and their hopes for future research in this area Papers from this meeting have now been published in this theme issue Interviewees Professor Richard Morris CBE FRS Professor Tim Bliss FRS Professor Graham Collingridge FRS meeting organisers Professor Terje Lømo Professor Mark Bear and Professor Min Zhuo Buy This issue will soon be available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016

    Original URL path: http://rstb.royalsocietypublishing.org/content/synaptic-plasticity-health-and-disease (2016-02-09)
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  • The paradigm shift for forensic science | Philosophical Transactions of the Royal Society B: Biological Sciences
    to halt the decline in public and judicial confidence in the abilities of scientists in the courtroom This theme issue examines what has transpired within the forensic science field in the 6 years since the wakeup call delivered by the US National Research Council report in 2009 Strengthening Forensic Science in the United States A Path Forward and lays the groundwork for what still needs to be done The two big messages emerging are that the underpinning quality of the science needs serious and significant redress and the ability of the scientists to communicate the science honesty and simply is paramount This issue results from a Royal Society discussion meeting held in February 2015 For more details please visit the website Read This issue is now available to read online Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Listen Audio recordings from the discussion meeting can be found here Click on the boxes next to speaker names to access the talk abstracts and recordings Buy This issue will soon be available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Please contact our sales team for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions Anniversary issue with free commentaries archive material videos and blogs Browse by subject behaviour biochemistry bioengineering bioinformatics biomaterials biomechanics biophysics biotechnology cellular biology cognition computational biology developmental biology ecology environmental science

    Original URL path: http://rstb.royalsocietypublishing.org/content/paradigm-shift-forensic-science (2016-02-09)
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  • Biological challenges to effective vaccines in the developing world | Philosophical Transactions of the Royal Society B: Biological Sciences
    high income countries limiting their health benefits The reasons for these differences are multiple and their interactions are complex New technology is beginning to unravel the role of human genetic variation microbial exposure maternal factors and nutrition in determining the immune response to vaccination In particular the application of high throughput sequencing and immunophenotyping technologies in clinical trials of vaccines is giving insights into immune mechanisms that can then be tested in the laboratory and used to design the next generation of vaccines This issue reviews our current state of knowledge reports recent findings based on these scientific advances and develops a research agenda for more effective vaccines and vaccination strategies This issue is based on a Royal Society Discussion Meeting held in November 2014 Details can be found here Read This issue is now available to read online Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Buy This issue is now available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Please contact our sales team for more information Listen This issue is based on a Royal Society Discussion Meeting held in November 2014 Audio recordings from the talks can be found here Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions Anniversary issue with free commentaries archive material videos and blogs Browse by subject behaviour biochemistry bioengineering bioinformatics biomaterials biomechanics biophysics biotechnology cellular biology cognition computational

    Original URL path: http://rstb.royalsocietypublishing.org/content/biological-challenges-effective-vaccines-developing-world (2016-02-09)
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  • Antimicrobial resistance: addressing the threat to global health | Philosophical Transactions of the Royal Society B: Biological Sciences
    Chief Medical Officer for England The issue covers perspectives on the problem from many different fields including scientific clinical public health veterinary industry and government The diversity of topics covered in this volume illustrates the complex interplay between many different fields of activity that influence our ability to address this growing threat to human health and the effective treatment of common microbial infections in hospital and community settings Read This issue is available to read online Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Buy This issue is now available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Please contact our sales team for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions Anniversary issue with free commentaries archive material videos and blogs Browse by

    Original URL path: http://rstb.royalsocietypublishing.org/content/antimicrobial-resistance-addressing-threat-global-health (2016-02-09)
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  • Climate change and vector-borne diseases of humans | Philosophical Transactions of the Royal Society B: Biological Sciences
    in prevalence and distribution The spread of disease vectors into temperate regions including Europe will cause significant public health issues if disease importation occurs Developing new tools to better map vectors and disease assess risk and plan public health interventions is therefore extremely important for tackling these diseases In this issue we report the latest findings on how a range of epidemiological environmental and socioeconomic factors are likely to govern the future impact of VBDs and assess the challenges in disentangling these factors Key results include the importance of biodiversity and evolution in emerging VBDs evidence for the link between climate warming and tick borne diseases the need to strengthen global efforts to reduce VBD burden the importance of climate on future cost effectiveness of current interventions against malaria predicted shifts in the distribution of mosquitoes that transmit dengue and chikungunya projected changes in onchocerciasis cases in certain regions of Africa and the importance of modelling in guiding future public health policy decisions Read This issue is now available to read online Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Buy This issue is now available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Please contact our sales team for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions Anniversary issue with free commentaries archive material videos and blogs Browse by subject behaviour biochemistry bioengineering

    Original URL path: http://rstb.royalsocietypublishing.org/content/climate-change-and-vector-borne-diseases-humans (2016-02-09)
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  • After 2015: infectious diseases in a new era of health and development | Philosophical Transactions of the Royal Society B: Biological Sciences
    a close in 2015 and a new set of goals will focus on poverty reduction and sustainable development In the area of health these new goals will take on non communicable diseases nutritional disorders mental health and injuries and risks linked to environmental and climate change There will be a marked shift in political support and funding as the prevention and control of infectious diseases is placed in a wider context At this critical juncture this volume of papers explores the frontiers of infection biology at the level of individuals molecular cellular genetic immune and populations demography ecology epidemiology It asks how efforts to investigate and control infections will fare in the era of sustainable development and how science can help to meet the challenge Read Read all articles from this issue online The Preface is FREE to access Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Watch An interview with guest editors Chris Dye and Anne O Garra Buy This issue is now available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions Anniversary issue with free commentaries archive material videos and blogs Browse by subject behaviour biochemistry bioengineering bioinformatics biomaterials biomechanics

    Original URL path: http://rstb.royalsocietypublishing.org/content/after-2015-infectious-diseases-new-era-health-and-development (2016-02-09)
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  • Ion channels, transporters and cancer | Philosophical Transactions of the Royal Society B: Biological Sciences
    so the cells interior changes leading to alterations in the activities of various enzymes acidity and structure scaffolding The cells ionic content is also controlled by exchangers that use the energy from the flow of one ion to transport a different ion In the case of cancer cells ion channel expression is aberrant proteins are expressed where they should not be upsetting their normal functioning Consequently the cells may go into over proliferation and or become anti social and invasive This imbalance is probably caused by hormones and hormone like chemicals known as growth factors well known to drive several cancers The articles contained in this volume show how various ion channels and transporters can contribute to the various stages of the cancer process from the initial formation of a primary tumour to the spreading of cancer The authors also illustrate how such proteins may be targeted so as to control the cancer using non toxic drugs Read Read all articles from this issue online The Introduction is FREE to access Don t have access If you would like to recommend this journal to your Librarian please fill out this form or contact sales royalsociety org Buy This issue is available to buy in print We offer discounts for bulk orders of the print version of this journal issue for educational use 20 per copy for 10 or more Authors of this issue can buy one copy at a discounted rate of 10 and further copies at 35 Please contact Jackie Knapp for more information Submit a theme proposal to Philosophical Transactions B February 2016 Volume 371 Issue 1688 Alert me to new content Philosophical Transactions of the Royal Society B Biological Sciences Influential themed journal issues across the life sciences Find out more Celebrating 350 years of Philosophical Transactions

    Original URL path: http://rstb.royalsocietypublishing.org/content/ion-channels-transporters-and-cancer (2016-02-09)
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