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  • Archives | Science Translational Medicine
    Jan 16 Vol 5 Iss 168 Jan 23 Vol 5 Iss 169 Jan 30 Vol 5 Iss 170 Feb 06 Vol 5 Iss 171 Feb 13 Vol 5 Iss 172 Feb 20 Vol 5 Iss 173 Feb 27 Vol 5 Iss 174 Mar 06 Vol 5 Iss 175 Mar 13 Vol 5 Iss 176 Mar 20 Vol 5 Iss 177 Mar 27 Vol 5 Iss 178 Apr 03 Vol 5 Iss 179 Apr 10 Vol 5 Iss 180 Apr 17 Vol 5 Iss 181 Apr 24 Vol 5 Iss 182 May 01 Vol 5 Iss 183 May 08 Vol 5 Iss 184 May 15 Vol 5 Iss 185 May 22 Vol 5 Iss 186 May 29 Vol 5 Iss 187 Jun 05 Vol 5 Iss 188 Jun 12 Vol 5 Iss 189 Jun 19 Vol 5 Iss 190 Jun 26 Vol 5 Iss 191 Jul 03 Vol 5 Iss 192 Jul 10 Vol 5 Iss 193 Jul 17 Vol 5 Iss 194 Jul 24 Vol 5 Iss 195 Jul 31 Vol 5 Iss 196 Aug 07 Vol 5 Iss 197 Aug 14 Vol 5 Iss 198 Aug 21 Vol 5 Iss 199 Aug 28 Vol 5 Iss 200 Sep 04 Vol 5 Iss 201 Sep 11 Vol 5 Iss 202 Sep 18 Vol 5 Iss 203 Sep 25 Vol 5 Iss 204 Oct 02 Vol 5 Iss 205 Oct 09 Vol 5 Iss 206 Oct 16 Vol 5 Iss 207 Oct 23 Vol 5 Iss 208 Oct 30 Vol 5 Iss 209 Nov 06 Vol 5 Iss 210 Nov 13 Vol 5 Iss 211 Nov 20 Vol 5 Iss 212 Nov 27 Vol 5 Iss 213 Dec 04 Vol 5 Iss 214 Dec 11 Vol 5 Iss 215 Dec 18 Vol 5 Iss 216 2012 2014 Science 5 February 2016

    Original URL path: http://stm.sciencemag.org/content/by/year/2013 (2016-02-10)
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  • Archives | Science Translational Medicine
    6 Iss 219 Jan 22 Vol 6 Iss 220 Jan 29 Vol 6 Iss 221 Feb 05 Vol 6 Iss 222 Feb 12 Vol 6 Iss 223 Feb 19 Vol 6 Iss 224 Feb 26 Vol 6 Iss 225 Mar 05 Vol 6 Iss 226 Mar 12 Vol 6 Iss 227 Mar 19 Vol 6 Iss 228 Mar 26 Vol 6 Iss 229 Apr 02 Vol 6 Iss 230 Apr 09 Vol 6 Iss 231 Apr 16 Vol 6 Iss 232 Apr 23 Vol 6 Iss 233 Apr 30 Vol 6 Iss 234 May 07 Vol 6 Iss 235 May 14 Vol 6 Iss 236 May 21 Vol 6 Iss 237 May 28 Vol 6 Iss 238 Jun 04 Vol 6 Iss 239 Jun 11 Vol 6 Iss 240 Jun 18 Vol 6 Iss 241 Jun 25 Vol 6 Iss 242 Jul 02 Vol 6 Iss 243 Jul 09 Vol 6 Iss 244 Jul 16 Vol 6 Iss 245 Jul 23 Vol 6 Iss 246 Jul 30 Vol 6 Iss 247 Aug 06 Vol 6 Iss 248 Aug 13 Vol 6 Iss 249 Aug 20 Vol 6 Iss 250 Aug 27 Vol 6 Iss 251 Sep 03 Vol 6 Iss 252 Sep 10 Vol 6 Iss 253 Sep 17 Vol 6 Iss 254 Sep 24 Vol 6 Iss 255 Oct 01 Vol 6 Iss 256 Oct 08 Vol 6 Iss 257 Oct 15 Vol 6 Iss 258 Oct 22 Vol 6 Iss 259 Oct 29 Vol 6 Iss 260 Nov 05 Vol 6 Iss 261 Nov 12 Vol 6 Iss 262 Nov 19 Vol 6 Iss 263 Nov 26 Vol 6 Iss 264 Dec 03 Vol 6 Iss 265 Dec 10 Vol 6 Iss 266 Dec 17 Vol 6 Iss 267 Dec 24 Vol 6 Iss 268 2013 2015 Science

    Original URL path: http://stm.sciencemag.org/content/by/year/2014 (2016-02-10)
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  • Archives | Science Translational Medicine
    2016 2000s 2010s 2009 2010 2011 2012 2013 2014 2015 2016 2016 Jan 06 Vol 8 Iss 320 Jan 13 Vol 8 Iss 321 Jan 20 Vol 8 Iss 322 Jan 27 Vol 8 Iss 323 Feb 03 Vol 8 Iss 324 2015 Science 5 February 2016 Vol 351 Issue 6273 Pages 539 630 Feature What makes DARPA tick Science and Society Taking race out of human genetics Agriculture Losing

    Original URL path: http://stm.sciencemag.org/content/by/year/2016 (2016-02-10)
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  • Table of Contents — January 06, 2016, 8 (320) | Science Translational Medicine
    Translational Medicine 06 Jan 2016 320ra2 Available antiretrovirals both for treatment and prevention and more comprehensive HIV testing would have prevented the majority of past annual HIV transmissions among MSM in the Netherlands but none of the three interventions in isolation Editor s Summary Abstract Full Text PDF Early memory phenotypes drive T cell proliferation in patients with pediatric malignancies By Nathan Singh Jessica Perazzelli Stephan A Grupp David M Barrett Science Translational Medicine 06 Jan 2016 320ra3 Enriching stem central memory cells rescues poor T cell expansion expanding patient eligibility for cellular therapy Editor s Summary Abstract Full Text PDF A mouse human phase 1 co clinical trial of a protease activated fluorescent probe for imaging cancer By Melodi Javid Whitley Diana M Cardona Alexander L Lazarides Ivan Spasojevic Jorge M Ferrer Joan Cahill Chang Lung Lee Matija Snuderl Dan G Blazer III E Shelley Hwang Rachel A Greenup Paul J Mosca Jeffrey K Mito Kyle C Cuneo Nicole A Larrier Erin K O Reilly Richard F Riedel William C Eward David B Strasfeld Dai Fukumura Rakesh K Jain W David Lee Linda G Griffith Moungi G Bawendi David G Kirsch Brian E Brigman Science Translational Medicine 06 Jan 2016 320ra4 A first in human phase 1 clinical trial of the PEGylated protease activated fluorescent probe LUM015 enables tumor imaging at a safe and tolerable dose in humans Editor s Summary Abstract Full Text PDF Editors Choice Is Huntington s disease a neurodevelopmental disorder By Kristen Brennand Science Translational Medicine 06 Jan 2016 320ec1 Gene expression analysis of patient derived Huntington s disease neural stem cells and corrected isogenic controls suggests that the first steps in disease pathogenesis may occur during fetal development Full Text Destiny or chance By Grzegorz Nalepa Science Translational Medicine 06 Jan 2016 320ec2 Cancers

    Original URL path: http://stm.sciencemag.org/content/8/320 (2016-02-10)
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  • Table of Contents — January 13, 2016, 8 (321) | Science Translational Medicine
    Mavoglurant in fragile X syndrome Results of two randomized double blind placebo controlled trials By Elizabeth Berry Kravis Vincent Des Portes Randi Hagerman Sébastien Jacquemont Perrine Charles Jeannie Visootsak Marc Brinkman Karin Rerat Barbara Koumaras Liansheng Zhu Gottfried Maria Barth Thomas Jaecklin George Apostol Florian von Raison Science Translational Medicine 13 Jan 2016 321ra5 In contrast to previous studies targeting the mGluR pathway in fragile X syndrome patients did not improve behavior independent of FMR1 methylation Editor s Summary Abstract Full Text PDF Repetitive blast exposure in mice and combat veterans causes persistent cerebellar dysfunction By James S Meabon Bertrand R Huber Donna J Cross Todd L Richards Satoshi Minoshima Kathleen F Pagulayan Ge Li Kole D Meeker Brian C Kraemer Eric C Petrie Murray A Raskind Elaine R Peskind David G Cook Science Translational Medicine 13 Jan 2016 321ra6 Ventral regions of the cerebellum in combat veterans and mice are vulnerable to long term traumatic brain injury caused by repetitive blast exposure Editor s Summary Abstract Full Text PDF Inhibition of diacylglycerol kinase α restores restimulation induced cell death and reduces immunopathology in XLP 1 By Elisa Ruffo Valeria Malacarne Sasha E Larsen Rupali Das Laura Patrussi Christoph Wülfing Christoph Biskup Senta M Kapnick Katherine Verbist Paige Tedrick Pamela L Schwartzberg Cosima T Baldari Ignacio Rubio Kim E Nichols Andrew L Snow Gianluca Baldanzi Andrea Graziani Science Translational Medicine 13 Jan 2016 321ra7 DGKα inhibition restores apoptosis in SAP deficient lymphocytes decreasing immunopathology in XLP 1 patients Editor s Summary Abstract Full Text PDF Cord blood monocyte derived inflammatory cytokines suppress IL 2 and induce nonclassic T H 2 type immunity associated with development of food allergy By Yuxia Zhang Fiona Collier Gaetano Naselli Richard Saffery Mimi LK Tang Katrina J Allen Anne Louise Ponsonby Leonard C Harrison Peter Vuillermin on behalf of the BIS Investigator Group Science Translational Medicine 13 Jan 2016 321ra8 Infants who develop food allergy display hyperresponsive innate immunity at birth that promotes nonclassical T H 2 differentiation Editor s Summary Abstract Full Text PDF Editors Choice Cancer care looks ROSEy By Marshaleen Henriques Forsythe Science Translational Medicine 13 Jan 2016 321ec5 Rapid on site evaluation ROSE potentially enhances bronchoscopic methods for lung cancer genotyping Full Text Clocking in to the brain s activity By Yo El Ju Science Translational Medicine 13 Jan 2016 321ec6 Aging alters the circadian rhythmicity of gene expression in the human brain Full Text Noncoding RNA plugs into a proinflammatory circuit By Alexander Marson Science Translational Medicine 13 Jan 2016 321ec7 Rmrp a long noncoding RNA and DDX5 an RNA helicase are potential therapeutic targets for autoimmunity Full Text An integrative analysis sheds light on methylation profiles By Masako Suzuki Science Translational Medicine 13 Jan 2016 321ec8 Genetic influence is not negligible for testing DNA methylation profiles in human studies Full Text Erratum Erratum for the Research Article CMV specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo by P J Hanley

    Original URL path: http://stm.sciencemag.org/content/8/321 (2016-02-10)
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  • Table of Contents — January 20, 2016, 8 (322) | Science Translational Medicine
    Gambetti Janis Blevins Shulin Zhang Yvonne Cohen Wei Chen Masahito Yamada Tsuyoshi Hamaguchi Nobuo Sanjo Hidehiro Mizusawa Yosikazu Nakamura Tetsuyuki Kitamoto Steven J Collins Alison Boyd Robert G Will Richard Knight Claudia Ponto Inga Zerr Theo F J Kraus Sabina Eigenbrod Armin Giese Miguel Calero Jesús de Pedro Cuesta Stéphane Haïk Jean Louis Laplanche Elodie Bouaziz Amar Jean Philippe Brandel Sabina Capellari Piero Parchi Anna Poleggi Anna Ladogana Anne H O Donnell Luria Konrad J Karczewski Jamie L Marshall Michael Boehnke Markku Laakso Karen L Mohlke Anna Kähler Kimberly Chambert Steven McCarroll Patrick F Sullivan Christina M Hultman Shaun M Purcell Pamela Sklar Sven J van der Lee Annemieke Rozemuller Casper Jansen Albert Hofman Robert Kraaij Jeroen G J van Rooij M Arfan Ikram André G Uitterlinden Cornelia M van Duijn Exome Aggregation Consortium ExAC Mark J Daly Daniel G MacArthur Science Translational Medicine 20 Jan 2016 322ra9 Large genomic reference data sets reveal a spectrum of pathogenicity in the prion protein gene and provide genetic validation for a therapeutic strategy in prion disease Editor s Summary Abstract Full Text PDF CXCR1 mediated neutrophil degranulation and fungal killing promote Candida clearance and host survival By Muthulekha Swamydas Ji Liang Gao Timothy J Break Melissa D Johnson Martin Jaeger Carlos A Rodriguez Jean K Lim Nathaniel M Green Amanda L Collar Brett G Fischer Chyi Chia Richard Lee John R Perfect Barbara D Alexander Bart Jan Kullberg Mihai G Netea Philip M Murphy Michail S Lionakis Science Translational Medicine 20 Jan 2016 322ra10 CXCR1 as a mediator of neutrophil fungal killing and host defense against systemic fungal infection in mice and humans Editor s Summary Abstract Full Text PDF Host gene expression classifiers diagnose acute respiratory illness etiology By Ephraim L Tsalik Ricardo Henao Marshall Nichols Thomas Burke Emily R Ko Micah T McClain Lori L Hudson Anna Mazur Debra H Freeman Tim Veldman Raymond J Langley Eugenia B Quackenbush Seth W Glickman Charles B Cairns Anja K Jaehne Emanuel P Rivers Ronny M Otero Aimee K Zaas Stephen F Kingsmore Joseph Lucas Vance G Fowler Jr Lawrence Carin Geoffrey S Ginsburg Christopher W Woods Science Translational Medicine 20 Jan 2016 322ra11 Pathogen specific host gene expression changes may combat inappropriate antibiotic use and emerging antibiotic resistance Editor s Summary Abstract Full Text PDF Editors Choice Stem cells lead the blind By Deniz Dalkara Science Translational Medicine 20 Jan 2016 322ec9 Embryonic stem cell derived retinas integrate and establish connections with remaining cells of degenerated monkey retinas Full Text A T cell memory problem By Roxana Dronca Science Translational Medicine 20 Jan 2016 322ec10 Memory T cells promote functional differentiation of naïve T cells and impair the antitumor efficacy of adoptive immunotherapy Full Text FGF21 How sweet it is By Gadi Lalazar Science Translational Medicine 20 Jan 2016 322ec11 The liver hormone fibroblast growth factor 21 suppresses sweet and alcohol preferences Full Text Podcast Science Translational Medicine Podcast 20 January 2016 By Eric Vallabh Minikel Sonia M Vallabh Annalisa M VanHook

    Original URL path: http://stm.sciencemag.org/content/8/322 (2016-02-10)
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  • Table of Contents — January 27, 2016, 8 (323) | Science Translational Medicine
    Beyond dermal filler and therapeutic carrier By Yi Zhu Clair Crewe Philipp E Scherer Science Translational Medicine 27 Jan 2016 323ps4 Adipose hyaluronan may be a therapeutic target for adipose tissue dysfunction during nutrient oversupply Abstract Full Text PDF Research Articles Complex effects of inhibiting hepatic apolipoprotein B100 synthesis in humans By Gissette Reyes Soffer Byoung Moon Antonio Hernandez Ono Marija Dionizovick Dimanovski Jhonsua Jimenez Joseph Obunike Tiffany Thomas Colleen Ngai Nelson Fontanez Daniel S Donovan Wahida Karmally Stephen Holleran Rajasekhar Ramakrishnan Robert S Mittleman Henry N Ginsberg Science Translational Medicine 27 Jan 2016 323ra12 Targeting apoB synthesis with mipomersen KYNAMRO can be effective for lowering plasma levels of apoB lipoproteins without reducing the secretion of VLDL Editor s Summary Abstract Full Text PDF USF1 deficiency activates brown adipose tissue and improves cardiometabolic health By Pirkka Pekka Laurila Jarkko Soronen Sander Kooijman Saara Forsström Mariëtte R Boon Ida Surakka Essi Kaiharju Claudia P Coomans Sjoerd A A Van Den Berg Anu Autio Antti Pekka Sarin Johannes Kettunen Emmi Tikkanen Tuula Manninen Jari Metso Reija Silvennoinen Krista Merikanto Maija Ruuth Julia Perttilä Anne Mäkelä Ayaka Isomi Anita M Tuomainen Anna Tikka Usama Abo Ramadan Ilkka Seppälä Terho Lehtimäki Johan Eriksson Aki Havulinna Antti Jula Pekka J Karhunen Veikko Salomaa Markus Perola Christian Ehnholm Miriam Lee Rueckert Miranda Van Eck Anne Roivainen Marja Riitta Taskinen Leena Peltonen Eero Mervaala Anu Jalanko Esa Hohtola Vesa M Olkkonen Samuli Ripatti Petri T Kovanen Patrick C N Rensen Anu Suomalainen Matti Jauhiainen Science Translational Medicine 27 Jan 2016 323ra13 Deficiency of USF1 protects against obesity insulin resistance and cardiovascular disease in mice and humans and induces brown adipose tissue to burn triglycerides and glucose Editor s Summary Abstract Full Text PDF Reviews The intersection of nonalcoholic fatty liver disease and obesity By Jennifer A Woo Baidal Joel E Lavine Science Translational Medicine 27 Jan 2016 323rv1 New insights into the overlap and differences between obesity and nonalcoholic fatty liver disease NAFLD are contributing to advances in diagnosis and treatment of NAFLD Abstract Full Text PDF New therapeutic approaches for the treatment of obesity By Alan R Saltiel Science Translational Medicine 27 Jan 2016 323rv2 Current and future pharmacological approaches to the treatment of obesity focus on the control of energy balance Abstract Full Text PDF Editors Choice Advance warning By Pamela Bhatti Science Translational Medicine 27 Jan 2016 323ec12 An algorithm transforms heart rate variability data into a warning sign for imminent epileptic seizure Full Text Hiding in plain sight By Nicole M Bouvier Science Translational Medicine 27 Jan 2016 323ec13 Even when it seems like we humans are winning against Mycobacterium tuberculosis we probably aren t Full Text A wealth of cells By Biju Parekkadan Science Translational Medicine 27 Jan 2016 323ec14 Expanding hematopoietic stem cells from umbilical cord blood with an aryl hydrocarbon antagonist could improve stem cell therapy Full Text Stemming the tide of ALS By Jeffrey Statland Science Translational Medicine 27 Jan 2016 323ec15 Mesenchymal stem cells engineered to secrete neurotrophic

    Original URL path: http://stm.sciencemag.org/content/8/323 (2016-02-10)
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  • Previous ASAs | Science Translational Medicine
    Chow Ph D Tore Eid M D Ph D Cyrus M Ghajar Ph D Christopher Gregg Ph D Ania M Jastreboff M D Ph D William J Mack M D F A H A Mustafa Mahfuz M D M P H Adam A Margolin Ph D Goutham Narla M D Ph D Benjamin Neale Ph D Trudy G Oliver Ph D Christopher R Polage M D Anne Schaefer M D Ph D Erkin Seker Ph D Anandi N Sheth M D Vikaas Sohal M D Ph D Amir Tirosh M D Ph D Adriano Tonelli M D Benjamin F Voight Ph D Deepak Voora M D David A Zidar M D Ph D Associate Scientific Advisors 2012 Niroshana Anandasabapathy M D Ph D Aaron B Baker Ph D Ruanne Barnabas M D Ph D Chetan Bettegowda M D Ph D Carolyn Calfee M D Joel H Collier Ph D Sarah Henrickson M D Ph D George A Mashour M D Ph D Heiko Methe M D Ph D Matthias Nahrendorf M D Ph D Takahisa Nakamura Ph D Jagdeep Obhrai M D Ernesto Oviedo Orta M D Ph D Marina Reznik M D Joshua Shrout Ph D Manpreet Singh M D Carsten Skarke M D Yvette Tanhehco M D Bryan G Yipp M D Amir Zeki M D Associate Scientific Advisors 2011 Rebecca Boxer M D Mickie H Cheng M D Ph D Samir Damani M D PharmD Ashkan Emadi M D Ph D Carmella Evans Molina M D Ph D Ruth Farrell M D Diane Gesty Palmer M D Ph D David S Hong M D Richard J Lin M D Ph D George A Mashour M D Ph D Carrie Nielson MPH Ph D Timothy B Niewold M D FACR Yevgeniya Nusinovich M D Ph D Melissa Nyendak

    Original URL path: http://stm.sciencemag.org/content/previous-asas (2016-02-10)
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