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  • Knitting Up the Raveled Sleave of Care | Science Translational Medicine
    on this site Garret A FitzGerald Institute for Translational Medicine and Therapeutics Smilow Center for Translational Research Perelman School of Medicine University of Pennsylvania Philadelphia PA 19104 USA Find this author on Google Scholar Find this author on PubMed Search for this author on this site Article Figures Data Info Metrics eLetters PDF Article Information vol 5 no 212 212rv3 DOI http dx doi org 10 1126 scitranslmed 3007225 PubMed 24259052 Published By American Association for the Advancement of Science Print ISSN 1946 6234 Online ISSN 1946 6242 History Received for publication 2 August 2013 Accepted for publication 16 October 2013 Copyright Usage Copyright 2013 American Association for the Advancement of Science Author Information Guangrui Yang 1 Georgios Paschos 1 Anne M Curtis 2 Erik S Musiek 3 Sarah C McLoughlin 1 and Garret A FitzGerald 1 1 Institute for Translational Medicine and Therapeutics Smilow Center for Translational Research Perelman School of Medicine University of Pennsylvania Philadelphia PA 19104 USA 2 Department of Biochemistry and Immunology Trinity Biomedical Sciences Institute Trinity College Dublin Dublin 2 Ireland 3 Department of Neurology Hope Center for Neurological Disorders Washington University School of Medicine St Louis MO 63110 USA Corresponding author E mail garret at upenn edu From Macbeth act 2 scene 2 by William Shakespeare AltMetrics No Altmetric data available for this article Article usage Abstract Full PDF Nov 2013 5106 361 297 Dec 2013 745 24 36 Jan 2014 346 20 18 Feb 2014 207 13 15 Mar 2014 210 10 15 Apr 2014 197 4 12 May 2014 139 4 6 Jun 2014 90 3 9 Jul 2014 147 2 13 Aug 2014 105 5 7 Sep 2014 116 5 13 Oct 2014 130 3 8 Nov 2014 81 7 10 Dec 2014 101 7 14 Jan 2015 105 3 6 Feb 2015 93 9 6 Mar 2015 105 4 7 Apr 2015 82 8 9 May 2015 71 3 6 Jun 2015 44 4 11 Jul 2015 17 1 0 Aug 2015 29 0 1 Sep 2015 16 0 0 Oct 2015 11 1 4 Nov 2015 16 1 8 Dec 2015 17 3 3 Jan 2016 36 2 3 Feb 2016 29 2 3 View Full Text Science Translational Medicine Vol 5 Issue 212 20 November 2013 Table of Contents Article Tools Email Thank you for your interest in spreading the word about Science Translational Medicine NOTE We only request your email address so that the person you are recommending the page to knows that you wanted them to see it and that it is not junk mail We do not capture any email address Your Email Your Name Send To Enter multiple addresses on separate lines or separate them with commas You are going to email the following Knitting Up the Raveled Sleave of Care Message Subject Your Name has forwarded a page to you from Science Translational Medicine Message Body Your Name thought you would like to see this page from the Science Translational Medicine web site

    Original URL path: http://stm.sciencemag.org/content/5/212/212rv3.article-info (2016-02-10)
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  • Knitting Up the Raveled Sleave of Care | Science Translational Medicine
    Louis MO 63110 USA Find this author on Google Scholar Find this author on PubMed Search for this author on this site Sarah C McLoughlin Institute for Translational Medicine and Therapeutics Smilow Center for Translational Research Perelman School of Medicine University of Pennsylvania Philadelphia PA 19104 USA Find this author on Google Scholar Find this author on PubMed Search for this author on this site Garret A FitzGerald Institute for Translational Medicine and Therapeutics Smilow Center for Translational Research Perelman School of Medicine University of Pennsylvania Philadelphia PA 19104 USA Find this author on Google Scholar Find this author on PubMed Search for this author on this site Article Figures Data Info Metrics eLetters PDF Submit a Response to This Article Compose eLetter Title Contents More information about text formats Plain text Plain text No HTML tags allowed Web page addresses and e mail addresses turn into links automatically Lines and paragraphs break automatically Upload Tables and Figures Attach tables e g doc and figures jpg gif tif by choosing the desired file and then uploading them below Add a new file Upload Files must be less than 100 MB Allowed file types doc jpg jpeg gif tif pdf File names can only contain the following characters A Z a z 0 9 Author Information Contributors First name and middle name First or given name e g Peter Last Name Your last or family name e g MacMoody Email Your email address e g higgs boson gmail com Role Occupation Your role and or occupation e g Orthopedic Surgeon Affiliation Your organization or institution if applicable e g Royal Free Hospital Add another contributor optional Statement of Competing Interests Competing interests Yes No Please describe the competing interests Highwire Comment Subject Apath Vertical Tabs Submit No eLetters have been published for this article View Full Text Science Translational Medicine Vol 5 Issue 212 20 November 2013 Table of Contents Article Tools Email Thank you for your interest in spreading the word about Science Translational Medicine NOTE We only request your email address so that the person you are recommending the page to knows that you wanted them to see it and that it is not junk mail We do not capture any email address Your Email Your Name Send To Enter multiple addresses on separate lines or separate them with commas You are going to email the following Knitting Up the Raveled Sleave of Care Message Subject Your Name has forwarded a page to you from Science Translational Medicine Message Body Your Name thought you would like to see this page from the Science Translational Medicine web site Your Personal Message Send Message Download Powerpoint Print Save to my folders User Name Password Remember my user name password Submit Alerts Please log in to add an alert for this article Username Enter your Sciencemag org username Password Enter the password that accompanies your username Log in Request Permissions Citation tools Knitting Up the Raveled Sleave of Care By Guangrui Yang

    Original URL path: http://stm.sciencemag.org/content/5/212/212rv3.e-letters (2016-02-10)
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  • Knitting Up the Raveled Sleave of Care | Science Translational Medicine
    Department of Biochemistry and Immunology Trinity Biomedical Sciences Institute Trinity College Dublin Dublin 2 Ireland Find this author on Google Scholar Find this author on PubMed Search for this author on this site Erik S Musiek Department of Neurology Hope Center for Neurological Disorders Washington University School of Medicine St Louis MO 63110 USA Find this author on Google Scholar Find this author on PubMed Search for this author on this site Sarah C McLoughlin Institute for Translational Medicine and Therapeutics Smilow Center for Translational Research Perelman School of Medicine University of Pennsylvania Philadelphia PA 19104 USA Find this author on Google Scholar Find this author on PubMed Search for this author on this site Garret A FitzGerald Institute for Translational Medicine and Therapeutics Smilow Center for Translational Research Perelman School of Medicine University of Pennsylvania Philadelphia PA 19104 USA Find this author on Google Scholar Find this author on PubMed Search for this author on this site Article Figures Data Info Metrics eLetters PDF Log in to view full text As a service to the community AAAS Science has made this article free with registration Username Enter your Sciencemag org username Password Enter the password that accompanies your username Forgot your username or password Log in Register for Free Join Subscribe Recommend a subscription to your library Help for librarians Science Translational Medicine Vol 5 Issue 212 20 November 2013 Table of Contents Article Tools Email Thank you for your interest in spreading the word about Science Translational Medicine NOTE We only request your email address so that the person you are recommending the page to knows that you wanted them to see it and that it is not junk mail We do not capture any email address Your Email Your Name Send To Enter multiple addresses on separate lines or separate them with commas You are going to email the following Knitting Up the Raveled Sleave of Care Message Subject Your Name has forwarded a page to you from Science Translational Medicine Message Body Your Name thought you would like to see this page from the Science Translational Medicine web site Your Personal Message Send Message Download Powerpoint Print Save to my folders User Name Password Remember my user name password Submit Alerts Please log in to add an alert for this article Username Enter your Sciencemag org username Password Enter the password that accompanies your username Log in Request Permissions Citation tools Knitting Up the Raveled Sleave of Care By Guangrui Yang Georgios Paschos Anne M Curtis Erik S Musiek Sarah C McLoughlin Garret A FitzGerald Science Translational Medicine 20 Nov 2013 212rv3 Recent advances in our understanding of molecular clocks highlight their relevance to human physiology and disease Citation Manager Formats BibTeX Bookends EasyBib EndNote tagged EndNote 8 xml Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share Knitting Up the Raveled Sleave of Care By Guangrui Yang Georgios Paschos Anne M Curtis Erik S Musiek Sarah C McLoughlin Garret A FitzGerald Science Translational Medicine

    Original URL path: http://stm.sciencemag.org/content/5/212/212rv3.full (2016-02-10)
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  • Table of Contents — November 20, 2013, 5 (212) | Science Translational Medicine
    of seminal plasma proteins ECM1 and TEX101 facilitate the differential diagnosis of azoospermia Editor s Summary Abstract Full Text PDF Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain By Eloise Hudry Jonathan Dashkoff Alysson D Roe Shuko Takeda Robert M Koffie Tadafumi Hashimoto Maria Scheel Tara Spires Jones Michal Arbel Ornath Rebecca Betensky Beverly L Davidson Bradley T Hyman Science Translational Medicine 20 Nov 2013 212ra161 Introduction of different APOE isoforms modulates Aβ peptide aggregation and neurotoxicity after amyloid deposition in mouse brain Editor s Summary Abstract Full Text PDF Pharmacological Inhibition of a MicroRNA Family in Nonhuman Primates by a Seed Targeting 8 Mer AntimiR By Veerle Rottiers Susanna Obad Andreas Petri Robert McGarrah Marie W Lindholm Joshua C Black Sumita Sinha Robin J Goody Matthew S Lawrence Andrew S deLemos Henrik F Hansen Steve Whittaker Steve Henry Rohn Brookes Seyed Hani Najafi Shoushtari Raymond T Chung Johnathan R Whetstine Robert E Gerszten Sakari Kauppinen Anders M Näär Science Translational Medicine 20 Nov 2013 212ra162 Long term treatment of obese insulin resistant nonhuman primates with a seed targeting antimiR oligonucleotide against the microRNA 33 family derepresses hepatic expression of miR 33 targets increases circulating HDL cholesterol and has a clean safety profile Editor s Summary Abstract Full Text PDF Quantitative Diagnosis of Malignant Pleural Effusions by Single Cell Mechanophenotyping By Henry T K Tse Daniel R Gossett Yo Sup Moon Mahdokht Masaeli Marie Sohsman Yong Ying Kimberly Mislick Ryan P Adams Jianyu Rao Dino Di Carlo Science Translational Medicine 20 Nov 2013 212ra163 Single cell biophysical properties were used for diagnosing malignant pleural effusions from patients Editor s Summary Abstract Full Text PDF Editors Choice Searching for Needles in the T Cell Receptor Haystack By Margaret K Callahan Science Translational Medicine 20 Nov 2013 212ec191 New technology permits high throughput identification and analysis of specific T cell receptors Full Text Removing Salt from the Wound By Tore Eid Science Translational Medicine 20 Nov 2013 212ec192 Central nervous system specific chloride extrusion enhancers show promise as therapeutics for neuropathic pain Full Text Mi Casa No Es Su Casa By Cyrus M Ghajar Science Translational Medicine 20 Nov 2013 212ec193 Leukemic stem cells that generate AML and CML may reside in distinct niches within the bone marrow microenvironment Full Text Nitric Oxide Signaling at the Heart of the Matter By Adriano R Tonelli Science Translational Medicine 20 Nov 2013 212ec194 Genetic mutations that affect the nitric oxide pathway and lead to accelerated clotting increase the risk of coronary heart disease Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe Submit About The Cover ONLINE COVER Mechanophenotyping Cancer cells have different mechanical properties than their healthier counterparts Malignant cells are more deformable than benign cells and such deformability can be used to diagnose

    Original URL path: http://stm.sciencemag.org/content/5/212 (2016-02-10)
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  • Table of Contents — November 20, 2013, 5 (212) | Science Translational Medicine
    Measurements of seminal plasma proteins ECM1 and TEX101 facilitate the differential diagnosis of azoospermia Editor s Summary Abstract Full Text PDF Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain By Eloise Hudry Jonathan Dashkoff Alysson D Roe Shuko Takeda Robert M Koffie Tadafumi Hashimoto Maria Scheel Tara Spires Jones Michal Arbel Ornath Rebecca Betensky Beverly L Davidson Bradley T Hyman Science Translational Medicine 20 Nov 2013 212ra161 Introduction of different APOE isoforms modulates Aβ peptide aggregation and neurotoxicity after amyloid deposition in mouse brain Editor s Summary Abstract Full Text PDF Pharmacological Inhibition of a MicroRNA Family in Nonhuman Primates by a Seed Targeting 8 Mer AntimiR By Veerle Rottiers Susanna Obad Andreas Petri Robert McGarrah Marie W Lindholm Joshua C Black Sumita Sinha Robin J Goody Matthew S Lawrence Andrew S deLemos Henrik F Hansen Steve Whittaker Steve Henry Rohn Brookes Seyed Hani Najafi Shoushtari Raymond T Chung Johnathan R Whetstine Robert E Gerszten Sakari Kauppinen Anders M Näär Science Translational Medicine 20 Nov 2013 212ra162 Long term treatment of obese insulin resistant nonhuman primates with a seed targeting antimiR oligonucleotide against the microRNA 33 family derepresses hepatic expression of miR 33 targets increases circulating HDL cholesterol and has a clean safety profile Editor s Summary Abstract Full Text PDF Quantitative Diagnosis of Malignant Pleural Effusions by Single Cell Mechanophenotyping By Henry T K Tse Daniel R Gossett Yo Sup Moon Mahdokht Masaeli Marie Sohsman Yong Ying Kimberly Mislick Ryan P Adams Jianyu Rao Dino Di Carlo Science Translational Medicine 20 Nov 2013 212ra163 Single cell biophysical properties were used for diagnosing malignant pleural effusions from patients Editor s Summary Abstract Full Text PDF Editors Choice Searching for Needles in the T Cell Receptor Haystack By Margaret K Callahan Science Translational Medicine 20 Nov 2013 212ec191 New technology permits high throughput identification and analysis of specific T cell receptors Full Text Removing Salt from the Wound By Tore Eid Science Translational Medicine 20 Nov 2013 212ec192 Central nervous system specific chloride extrusion enhancers show promise as therapeutics for neuropathic pain Full Text Mi Casa No Es Su Casa By Cyrus M Ghajar Science Translational Medicine 20 Nov 2013 212ec193 Leukemic stem cells that generate AML and CML may reside in distinct niches within the bone marrow microenvironment Full Text Nitric Oxide Signaling at the Heart of the Matter By Adriano R Tonelli Science Translational Medicine 20 Nov 2013 212ec194 Genetic mutations that affect the nitric oxide pathway and lead to accelerated clotting increase the risk of coronary heart disease Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe Submit About The Cover ONLINE COVER Mechanophenotyping Cancer cells have different mechanical properties than their healthier counterparts Malignant cells are more deformable than benign cells and such deformability can be used to

    Original URL path: http://stm.sciencemag.org/content/5/212.toc (2016-02-10)
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  • McLoughlin Sarah C AU FitzGerald Garret A TI Knitting Up the Raveled Sleave of Care DP 2013 Dec 20 TA Science Translational Medicine PG 212rv3 212rv3 VI 5 IP 212 4099 http stm sciencemag org content 5 212 212rv3 short 4100 http stm sciencemag org content 5 212 212rv3 full AB This Review is based on the Franklin Epstein Lecture delivered at Beth Israel Deaconess Hospital on 25 April 2013

    Original URL path: http://stm.sciencemag.org/highwire/citation/186989/medlars (2016-02-10)
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  • McLoughlin Sarah C A1 FitzGerald Garret A T1 Knitting Up the Raveled Sleave of Care JF Science Translational Medicine YR 2013 FD American Association for the Advancement of Science VO 5 IS 212 SP 212rv3 OP 212rv3 DO 10 1126 scitranslmed 3007225 UL http stm sciencemag org content 5 212 212rv3 abstract AB This Review is based on the Franklin Epstein Lecture delivered at Beth Israel Deaconess Hospital on 25

    Original URL path: http://stm.sciencemag.org/highwire/citation/186989/refworks (2016-02-10)
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  • Sepsis: Up Against the Clock | Science Translational Medicine
    view full text As a service to the community AAAS Science has made this article free with registration Username Enter your Sciencemag org username Password Enter the password that accompanies your username Forgot your username or password Log in Register for Free Join Subscribe Recommend a subscription to your library Help for librarians Science Translational Medicine Vol 4 Issue 125 14 March 2012 Table of Contents Article Tools Email Thank you for your interest in spreading the word about Science Translational Medicine NOTE We only request your email address so that the person you are recommending the page to knows that you wanted them to see it and that it is not junk mail We do not capture any email address Your Email Your Name Send To Enter multiple addresses on separate lines or separate them with commas You are going to email the following Sepsis Up Against the Clock Message Subject Your Name has forwarded a page to you from Science Translational Medicine Message Body Your Name thought you would like to see this page from the Science Translational Medicine web site Your Personal Message Send Message Save to my folders User Name Password Remember my user name password Submit Alerts Please log in to add an alert for this article Username Enter your Sciencemag org username Password Enter the password that accompanies your username Log in Request Permissions Citation tools Sepsis Up Against the Clock By Bryan G Yipp Science Translational Medicine 14 Mar 2012 125ec47 The innate immune system is linked to circadian rhythms through the cyclical expression of TLR9 and this regulation impacts septic shock Citation Manager Formats BibTeX Bookends EasyBib EndNote tagged EndNote 8 xml Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Share Sepsis Up Against the Clock By Bryan G Yipp Science

    Original URL path: http://stm.sciencemag.org/content/4/125/125ec47 (2016-02-10)
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