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  • Table of Contents — July 28, 2010, 2 (42) | Science Translational Medicine
    therapy Abstract Full Text PDF Research Articles Function of an Implanted Tissue Glucose Sensor for More than 1 Year in Animals By David A Gough Lucas S Kumosa Timothy L Routh Joe T Lin Joseph Y Lucisano Science Translational Medicine 28 Jul 2010 42ra53 An implanted tissue glucose sensor can provide stable readings of glucose concentrations for more than a year Editor s Summary Abstract Full Text PDF A Human Specific Deletion in Mouse Cmah Increases Disease Severity in the mdx Model of Duchenne Muscular Dystrophy By Kumaran Chandrasekharan Jung Hae Yoon Ying Xu Sarah deVries Marybeth Camboni Paulus M L Janssen Ajit Varki Paul T Martin Science Translational Medicine 28 Jul 2010 42ra54 A mouse model for Duchenne muscular dystrophy engineered to produce human like glycosylation mimics the human disease better than existing models Editor s Summary Abstract Full Text PDF Editors Choice A Stem Cell Factory in the Making By Shama Ahmad Science Translational Medicine 28 Jul 2010 42ec118 Culturing muscle stem cells on bioengineered substrates that mimic the cells in vivo niche improves their ability to replicate Full Text Depressed Brains Inflict Pain By Michael J Minzenberg Science Translational Medicine 28 Jul 2010 42ec119 A new study suggests that the pain experienced from migraines may result from cortical spreading depression Full Text Power in Numbers By Alexei Morozov Science Translational Medicine 28 Jul 2010 42ec120 A multidisciplinary effort begins to unravel the genomic portrait of prostate cancer Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe Submit About The Cover ONLINE COVER Signal from the Inside This 3 to 4 cm sealed titanium button contains everything you need

    Original URL path: http://stm.sciencemag.org/content/2/42 (2016-02-10)
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  • Table of Contents — August 04, 2010, 2 (43) | Science Translational Medicine
    William Arthur Rich A Klinghoffer Diana Gargano Lixia Li Igor Feldman Bethany Lynch John Rush Ronald C Hendrickson Peter Blume Jensen Cloud P Paweletz Science Translational Medicine 04 Aug 2010 43ra55 Phosphorylation sites on proteins in the phosphatidylinositol 3 kinase pathway that are regulated by candidate drugs can serve as useful biomarkers to predict tumor sensitivity to AKT inhibitors Editor s Summary Abstract Full Text PDF Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis By Zandra K Pinnix Lance D Miller Wei Wang Ralph D Agostino Jr Tim Kute Mark C Willingham Heather Hatcher Lia Tesfay Guangchao Sui Xiumin Di Suzy V Torti Frank M Torti Science Translational Medicine 04 Aug 2010 43ra56 An iron efflux pump is a pivotal protein in breast cancer biology and a strong and independent predictor of breast cancer prognosis Editor s Summary Abstract Full Text PDF Editors Choice Reducing the UnSIRTainty of Alzheimer s Disease By Joshi Alumkal Science Translational Medicine 04 Aug 2010 43ec121 The deacetylase SIRT1 suppresses the production of Alzheimer s disease associated β amyloid by activating a gene encoding a key proteolytic enzyme Full Text The Promise of C Type Natriuretic Peptide for Weight Loss By Rhonda Bentley Lewis Science Translational Medicine 04 Aug 2010 43ec122 A recently described hormone C type natriuretic peptide decreases food intake and therefore body weight and increases energy expenditure Full Text A Shot at Cancer Prevention By Elaine Cheng Science Translational Medicine 04 Aug 2010 43ec123 Vaccination with α lactalbumin provides prophylaxis against breast cancer in tumor prone mouse models Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe Submit About The Cover

    Original URL path: http://stm.sciencemag.org/content/2/43 (2016-02-10)
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  • Table of Contents — August 11, 2010, 2 (44) | Science Translational Medicine
    PDF Research Articles Bacteria Induced Gap Junctions in Tumors Favor Antigen Cross Presentation and Antitumor Immunity By Fabiana Saccheri Chiara Pozzi Francesca Avogadri Sara Barozzi Mario Faretta Paola Fusi Maria Rescigno Science Translational Medicine 11 Aug 2010 44ra57 Bacterial infection induces extra gap junctions in tumors through which tumor antigens travel to antigen presenting cells triggering an effective antitumor immune response Editor s Summary Abstract Full Text PDF Fatty Acid Oxidation and Malonyl CoA Decarboxylase in the Vascular Remodeling of Pulmonary Hypertension By Gopinath Sutendra Sebastien Bonnet Gael Rochefort Alois Haromy Karalyn D Folmes Gary D Lopaschuk Jason R B Dyck Evangelos D Michelakis Science Translational Medicine 11 Aug 2010 44ra58 The overgrowth of vascular cells that causes pulmonary hypertension can be prevented in mice by inhibiting a metabolic shift toward glycolysis Editor s Summary Abstract Full Text PDF Editors Choice Making Research Reproducible By Nichole Carlson Science Translational Medicine 11 Aug 2010 44ec124 Reproducible research requires that the hows and whys of statistical methods be made widely available Full Text Genomic and Stem Cell Technologies Collide By Samir Damani Science Translational Medicine 11 Aug 2010 44ec125 Pluripotent stem cells are used to model Long QT syndromes and explain the functional effects of a prominent mutation in the KCNQ1 gene Full Text Rebuilding Broken Bones with Bioactive Ceramics By Kenneth W Ng Science Translational Medicine 11 Aug 2010 44ec126 Novel bioactive ceramics may allow orthopedic trauma surgeons to better repair shattered bones Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe Submit About The Cover ONLINE COVER Pulmonary Perfusion Lung arterial vessels as shown here in a tiny barium angiogram from

    Original URL path: http://stm.sciencemag.org/content/2/44 (2016-02-10)
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  • Table of Contents — August 18, 2010, 2 (45) | Science Translational Medicine
    Shwu Huey Liu Yung Chi Cheng Science Translational Medicine 18 Aug 2010 45ra59 A traditional Chinese medicine reduces the intestinal toxicity of chemotherapy by inhibiting inflammation and promoting cell proliferation Editor s Summary Abstract Full Text PDF Multivalent Integrin Specific Ligands Enhance Tissue Healing and Biomaterial Integration By Timothy A Petrie Jenny E Raynor David W Dumbauld Ted T Lee Subodh Jagtap Kellie L Templeman David M Collard Andrés J García Science Translational Medicine 18 Aug 2010 45ra60 Titanium implants coated with nanoclustered ligands for integrin adhesion receptors are tightly integrated into bone for orthopedic applications Editor s Summary Abstract Full Text PDF Editors Choice Antibodies Against TIM 1 for Asthma Therapy By Shama Ahmad Science Translational Medicine 18 Aug 2010 45ec127 Blocking specific sites on TIM 1 reduces asthmatic responses Full Text Hot Peppers to Cool Blood Pressure By Christoph Buettner Science Translational Medicine 18 Aug 2010 45ec128 Feeding hypertensive rodents the pungent compound capsaicin reduces their blood pressure via activation of a cation channel Full Text Early Meeting Sets the Fate By Michael J Minzenberg Science Translational Medicine 18 Aug 2010 45ec129 Proteins implicated in Alzheimer s disease and schizophrenia are linked in brain development Full Text The Heart of Stemness By Alexei Morozov Science Translational Medicine 18 Aug 2010 45ec130 A regulator of asymmetric cell division promotes the transition to blast crisis in chronic myelogenous leukemia Full Text Podcast Science Translational Medicine Podcast 18 August 2010 By Yung Chi Cheng Annalisa M VanHook Science Translational Medicine 18 Aug 2010 45pc6 A conversation with Yung Chi Cheng about the effectiveness of a Chinese herbal medicine for treating the gastrointestinal side effects of chemotherapy Abstract More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards

    Original URL path: http://stm.sciencemag.org/content/2/45 (2016-02-10)
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  • Table of Contents — August 25, 2010, 2 (46) | Science Translational Medicine
    Biosynthetic Alternative to Human Donor Tissue for Inducing Corneal Regeneration 24 Month Follow Up of a Phase 1 Clinical Study By Per Fagerholm Neil S Lagali Kimberley Merrett W Bruce Jackson Rejean Munger Yuwen Liu James W Polarek Monica Söderqvist May Griffith Science Translational Medicine 25 Aug 2010 46ra61 A biosynthetic cornea is stably integrated with host tissues for 2 years after implantation and produces nerve regeneration and vision improvement Editor s Summary Abstract Full Text PDF Drug Reaction with Eosinophilia and Systemic Symptoms DRESS A Multiorgan Antiviral T Cell Response By Damien Picard Baptiste Janela Vincent Descamps Michel D Incan Philippe Courville Serge Jacquot Sylvie Rogez Laurent Mardivirin Hélène Moins Teisserenc Antoine Toubert Jacques Benichou Pascal Joly Philippe Musette Science Translational Medicine 25 Aug 2010 46ra62 A dangerous drug reaction may be caused by a severe immune response to reactivated resident herpes viruses Editor s Summary Abstract Full Text PDF Editors Choice Abrogating Angiogenesis Just Got EZier By Joshi Alumkal Science Translational Medicine 25 Aug 2010 46ec131 The EZH2 histone methyltransferase regulates tumor angiogenesis and can be targeted to tumors with small interfering RNAs Full Text Another Step Toward a Cure for Type 1 Diabetes Mellitus By Rhonda Bentley Lewis Science Translational Medicine 25 Aug 2010 46ec132 A drug currently used to prevent organ transplant rejection can avert type 1 diabetes in rats while maintaining immune system activation Full Text A Better Means of Modeling Data By Nichole Carlson Science Translational Medicine 25 Aug 2010 46ec133 New approximations for Bayesian estimation make its use more computationally feasible Full Text The Making of a New Lung By Elaine Cheng Science Translational Medicine 25 Aug 2010 46ec134 Creation of a bioartificial lung is successful for transplantation in the treatment of end stage lung disease Full Text Erratum A Correction to the

    Original URL path: http://stm.sciencemag.org/content/2/46 (2016-02-10)
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  • Table of Contents — September 01, 2010, 2 (47) | Science Translational Medicine
    Bordes Jean François Viallard Claire Goulvestre Jean Luc Pellegrin Bernard Weil Jean François Moreau Frédéric Batteux Patrick Blanco Science Translational Medicine 01 Sep 2010 47ra63 In the autoimmune disease lupus platelets activated by self antigens contribute to pathology by triggering the secretion of interferon from immune cells Editor s Summary Abstract Full Text PDF Overlap and Effective Size of the Human CD8 T Cell Receptor Repertoire By Harlan S Robins Santosh K Srivastava Paulo V Campregher Cameron J Turtle Jessica Andriesen Stanley R Riddell Christopher S Carlson Edus H Warren Science Translational Medicine 01 Sep 2010 47ra64 Deep sequencing of the T cell receptor repertoires of seven healthy adults reveals that the adaptive immune system is far less diverse than expected and the person to person overlap is thousands of times larger Editor s Summary Abstract Full Text PDF Editors Choice Immune Regulators Not Just for Type 1 Diabetes Anymore By Andrew A Bremer Science Translational Medicine 01 Sep 2010 47ec135 Stimulation of 4 1BB with an agonistic antibody reduces adiposity and body weight modulates inflammatory cytokine levels improves glucose lipid metabolism and increases energy expenditure suggesting a role for 4 1BB in the management of obesity and metabolic disorders Full Text SORTing Out Lipids By Samir Damani Science Translational Medicine 01 Sep 2010 47ec136 A gene encoding a protein that helps to sort and clear cellular proteins is the most common genetic contributor to plasma LDL concentrations Full Text Spy vs Spy Recruiting Stem Cells to the War on Cancer By Kenneth W Ng Science Translational Medicine 01 Sep 2010 47ec137 Mesenchymal stem cells can home in and deliver drug carrying nanoparticles to brain tumors Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and

    Original URL path: http://stm.sciencemag.org/content/2/47 (2016-02-10)
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  • Table of Contents — September 08, 2010, 2 (48) | Science Translational Medicine
    By Suchi Saria Anand K Rajani Jeffrey Gould Daphne Koller Anna A Penn Science Translational Medicine 08 Sep 2010 48ra65 Physiological parameters routinely and noninvasively collected in the first 3 hours of life can accurately predict morbidity in premature infants Editor s Summary Abstract Full Text PDF Nuclear Phospho Akt Increase Predicts Synergy of PI3K Inhibition and Doxorubicin in Breast and Ovarian Cancer By Jeffrey J Wallin Jane Guan Wei Wei Prior Kyle A Edgar Robert Kassees Deepak Sampath Marcia Belvin Lori S Friedman Science Translational Medicine 08 Sep 2010 48ra66 Akt phosphorylation in response to DNA damage predicts the sensitivity of cancer cells to combinations of a PI3K inhibitor and the replication inhibitor doxorubicin Editor s Summary Abstract Full Text PDF Editors Choice Amnion Epithelial Cells Cell Therapy Going Green By Shama Ahmad Science Translational Medicine 08 Sep 2010 48ec138 Recycling human amnion allows the production of stemlike cells that differentiate into airway epithelium and soothe injured lungs Full Text Act ing Against Muscle Loss in Cachexia By Christoph Buettner Science Translational Medicine 08 Sep 2010 48ec139 Inhibition of a TGF β family receptor prevents muscle loss and improves survival in cancer cachexia Full Text Power Failure Leads to Paralysis By Michael J Minzenberg Science Translational Medicine 08 Sep 2010 48ec140 The mutant enzyme SOD1 alters energy regulation in amyotrophic lateral sclerosis by direct interaction with a mitochondrial ion channel Full Text Small But Powerful By Alexei Morozov Science Translational Medicine 08 Sep 2010 48ec141 Lymphoma in mice is addicted to the microRNA miR 21 vanishing when the oncomir is removed Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe

    Original URL path: http://stm.sciencemag.org/content/2/48 (2016-02-10)
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  • Table of Contents — September 15, 2010, 2 (49) | Science Translational Medicine
    gene specific analysis of DNA methylation in the same individuals over a decade apart identifies a personalized epigenomic signature that may correlate with a common genetic trait Editor s Summary Abstract Full Text PDF Disruption at the PTCHD1 Locus on Xp22 11 in Autism Spectrum Disorder and Intellectual Disability By Abdul Noor Annabel Whibley Christian R Marshall Peter J Gianakopoulos Amelie Piton Andrew R Carson Marija Orlic Milacic Anath C Lionel Daisuke Sato Dalila Pinto Irene Drmic Carolyn Noakes Lili Senman Xiaoyun Zhang Rong Mo Julie Gauthier Jennifer Crosbie Alistair T Pagnamenta Jeffrey Munson Annette M Estes Andreas Fiebig Andre Franke Stefan Schreiber Alexandre F R Stewart Robert Roberts Ruth McPherson Stephen J Guter Edwin H Cook Jr Geraldine Dawson Gerard D Schellenberg Agatino Battaglia Elena Maestrini Autism Genome Project Consortium Linda Jeng Terry Hutchison Evica Rajcan Separovic Albert E Chudley Suzanne M E Lewis Xudong Liu Jeanette J Holden Bridget Fernandez Lonnie Zwaigenbaum Susan E Bryson Wendy Roberts Peter Szatmari Louise Gallagher Michael R Stratton Jozef Gecz Angela F Brady Charles E Schwartz Russell J Schachar Anthony P Monaco Guy A Rouleau Chi chung Hui F Lucy Raymond Stephen W Scherer John B Vincent Science Translational Medicine 15 Sep 2010 49ra68 Mutations of the X linked gene PTCHD1 are associated with autism spectrum disorders and intellectual disability Editor s Summary Abstract Full Text PDF Editors Choice A New Fix for Cancer By Joshi Alumkal Science Translational Medicine 15 Sep 2010 49ec142 Overexpression of an oncogenic microRNA leads to pre B cell lymphoma Full Text Next Generation Sequencing A Better Way By Nichole Carlson Science Translational Medicine 15 Sep 2010 49ec143 The cost of next generation sequencing can be lowered without loss of power by pooling samples from more subjects and sequencing at a lower depth Full Text Molecular Snapshot

    Original URL path: http://stm.sciencemag.org/content/2/49 (2016-02-10)
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