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  • Table of Contents — September 22, 2010, 2 (50) | Science Translational Medicine
    with possible relevance for the treatment of metastatic cancer Full Text Beating Heart Disease in Diabetes By Andrew A Bremer Science Translational Medicine 22 Sep 2010 50ec146 An apoA I mimetic that prevents fatty lesion formation in diabetic mice may prevent premature heart disease in patients with diabetes Full Text Antiplatelet Therapy To Genotype or Not By Samir Damani Science Translational Medicine 22 Sep 2010 50ec147 A recent study does not overturn the conclusion that DNA sequence polymorphisms in the hepatic cytochrome 2C19 gene are predictive of future adverse cardiovascular events Full Text Breath of Fresh Air Tissue Engineered Tracheas for Airway Repair By Kenneth W Ng Science Translational Medicine 22 Sep 2010 50ec148 Tissue engineered tracheas move one step closer as a clinical treatment Full Text Letters Comment on The Origins of Sexually Transmitted HIV Among Men Who Have Sex with Men By Laura Heath Lisa M Frenkel Brian T Foley James I Mullins Science Translational Medicine 22 Sep 2010 50le1 Unexpected diversity of HIV strains in infected patients reported by Butler et al indicates that there are problems with the validity of the analysis and therefore the conclusion that seminal plasma is the main source of infecting virus Editor s Summary Abstract Full Text PDF Response to Comment on The Origins of Sexually Transmitted HIV Among Men Who Have Sex with Men By Davey Smith Wayne Delport David Butler Susan Little Douglas Richman Sergei Kosakovsky Pond Science Translational Medicine 22 Sep 2010 50lr1 The excessive viral diversity noted by Heath et al in our sample of infected HIV patients prompted us to reexamine our data Doing so uncovered several mislabeled samples but no sources of contamination were identified Investigations into additional transmission pairs will be needed to further investigate these issues Editor s Summary Abstract Full Text PDF

    Original URL path: http://stm.sciencemag.org/content/2/50 (2016-02-10)
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  • Table of Contents — September 29, 2010, 2 (51) | Science Translational Medicine
    Joseph F Kelleher Stefan Peukert Shifeng Pan Xu Wu Sauveur Michel Maira Carlos García Echeverría Kimberly J Briggs D Neil Watkins Yung mae Yao Christoph Lengauer Markus Warmuth William R Sellers Marion Dorsch Science Translational Medicine 29 Sep 2010 51ra70 Resistance of medulloblastoma to Smo antagonists can be delayed or prevented by specific drug combinations Editor s Summary Abstract Full Text PDF A Central Role for Free Heme in the Pathogenesis of Severe Sepsis By Rasmus Larsen Raffaella Gozzelino Viktória Jeney László Tokaji Fernando A Bozza André M Japiassú Dolores Bonaparte Moisés Marinho Cavalcante Ângelo Chora Ana Ferreira Ivo Marguti Sílvia Cardoso Nuno Sepúlveda Ann Smith Miguel P Soares Science Translational Medicine 29 Sep 2010 51ra71 Heme from red blood cells released in septic shock worsens organ dysfunction and increases the risk of death but can be overcome by a scavenger of free heme Editor s Summary Abstract Full Text PDF Editors Choice Improving Stem Cell Survival One Hurdle at a Time By Shama Ahmad Science Translational Medicine 29 Sep 2010 51ec149 Inhibition of nonmuscle myosin II improves survival and supports self renewal of human pluripotent stem cells Full Text GPR120 Mediates the Benefits of Fish Oil By Christoph Buettner Science Translational Medicine 29 Sep 2010 51ec150 GPR120 an ω 3 fatty acid sensor expressed in macrophages and fat cells exerts anti inflammatory and insulin like effects Full Text Rewiring the Brain After Stroke By Michael J Minzenberg Science Translational Medicine 29 Sep 2010 51ec151 A new study finds altered communication between the brain s hemispheres after stroke Full Text When the Guardian Looks Away By Alexei Morozov Science Translational Medicine 29 Sep 2010 51ec152 The same single nucleotide polymorphism in the p53 regulator MDM2 increases cancer risk in mice but is a marker of less aggressive prostate cancer in

    Original URL path: http://stm.sciencemag.org/content/2/51 (2016-02-10)
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  • Table of Contents — October 06, 2010, 2 (52) | Science Translational Medicine
    Naomi S Falk David S Chu David Callanan Quan Dong Nguyen the Uveitis Study Group Kristine Rose Asifa Haider Franco Di Padova Science Translational Medicine 06 Oct 2010 52ra72 A human antibody to interleukin 17A is well tolerated and may be effective in the treatment of psoriasis rheumatoid arthritis and noninfectious uveitis Editor s Summary Abstract Full Text PDF PGC 1 α A Potential Therapeutic Target for Early Intervention in Parkinson s Disease By Bin Zheng Zhixiang Liao Joseph J Locascio Kristen A Lesniak Sarah S Roderick Marla L Watt Aron C Eklund Yanli Zhang James Peter D Kim Michael A Hauser Edna Grünblatt Linda B Moran Silvia A Mandel Peter Riederer Renee M Miller Howard J Federoff Ullrich Wüllner Spyridon Papapetropoulos Moussa B Youdim Ippolita Cantuti Castelvetri Anne B Young Jeffery M Vance Richard L Davis John C Hedreen Charles H Adler Thomas G Beach Manuel B Graeber Frank A Middleton Jean Christophe Rochet Clemens R Scherzer the Global PD Gene Expression GPEX Consortium Science Translational Medicine 06 Oct 2010 52ra73 Abnormal expression of genes for energy regulation in Parkinson s disease patients identifies a master regulator as a possible therapeutic target for early intervention Editor s Summary Abstract Full Text PDF Editors Choice Turning Off the Cancer Switch By Joshi Alumkal Science Translational Medicine 06 Oct 2010 52ec153 A new drug that blocks BMK1 inhibits tumor growth with minimal toxicity Full Text PANDERing to the Liver in Glucose Control By Rhonda Bentley Lewis Science Translational Medicine 06 Oct 2010 52ec154 A new cytokine like protein produced by the pancreas regulates glucose production in the liver during fasting Full Text Making Comparative Effectiveness Research Useful By Nichole Carlson Science Translational Medicine 06 Oct 2010 52ec155 The value of comparative effectiveness research depends on applying appropriate design and analysis principles

    Original URL path: http://stm.sciencemag.org/content/2/52 (2016-02-10)
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  • Table of Contents — October 13, 2010, 2 (53) | Science Translational Medicine
    Maria Kahn Tony Phan Ian M Orme Thomas S Vedvick Susan L Baldwin Rhea N Coler Steven G Reed Science Translational Medicine 13 Oct 2010 53ra74 A vaccine with a four protein fusion peptide from Mycobacterium tuberculosis effectively boosts the current childhood TB vaccine and protects against drug resistant TB Editor s Summary Abstract Full Text PDF PTEN Deficiency in Endometrioid Endometrial Adenocarcinomas Predicts Sensitivity to PARP Inhibitors By Konstantin J Dedes Daniel Wetterskog Ana M Mendes Pereira Rachael Natrajan Maryou B Lambros Felipe C Geyer Radost Vatcheva Kay Savage Alan Mackay Christopher J Lord Alan Ashworth Jorge S Reis Filho Science Translational Medicine 13 Oct 2010 53ra75 Endometrioid endometrial cancer cell lines harboring PTEN loss of function have impaired homologous recombination response to DNA double strand breaks and show an exquisite sensitivity to PARP inhibition Editor s Summary Abstract Full Text PDF Editors Choice Fatty Eggs and Infertility By Andrew A Bremer Science Translational Medicine 13 Oct 2010 53ec157 Lipotoxicity in ovarian cells may account for the reduced fertility observed in obese women Full Text New Cause for Diabetic Nephropathy By Christoph Buettner Science Translational Medicine 13 Oct 2010 53ec158 The deletion of the insulin receptor only in kidney podocytes induces diabetic nephropathy in mice Full Text Mapping Human Disease Risk By Samir Damani Science Translational Medicine 13 Oct 2010 53ec159 A third generation human HapMap will help to decode the heritable component of human disease risk Full Text To Vaccinate or Not Parents Decide By Donna E Hansel Science Translational Medicine 13 Oct 2010 53ec160 Although prophylactic human papillomavirus vaccines now are available fewer than 20 of girls 9 to 26 years of age have completed the three dose series Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational

    Original URL path: http://stm.sciencemag.org/content/2/53 (2016-02-10)
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  • Table of Contents — October 20, 2010, 2 (54) | Science Translational Medicine
    Svenningsson Paul Greengard Michael G Kaplitt Science Translational Medicine 20 Oct 2010 54ra76 Reduction of the 5 HT 1B receptor binding protein p11 in the mouse nucleus accumbens induces depression like behaviors and gene therapy to restore p11 expression in this region reverses depression like behaviors Editor s Summary Abstract Full Text PDF An Integrated Genomic and Epigenomic Approach Predicts Therapeutic Response to Zebularine in Human Liver Cancer By Jesper B Andersen Valentina M Factor Jens U Marquardt Chiara Raggi Yun Han Lee Daekwan Seo Elizabeth A Conner Snorri S Thorgeirsson Science Translational Medicine 20 Oct 2010 54ra77 Drug induced transcription and epigenetic changes can predict whether liver cancer can be successfully treated with an epigenome targeting drug Editor s Summary Abstract Full Text PDF Editors Choice When Too Much Oxygen Is Not Too Much By Shama Ahmad Science Translational Medicine 20 Oct 2010 54ec161 Breast regression protein 39 and YKL 40 regulate hyperoxia induced acute lung injury in mouse and human lung Full Text Blunting Pain at a Distance By Michael J Minzenberg Science Translational Medicine 20 Oct 2010 54ec162 Anandamide a natural transmitter stimulates cannabinoid receptors located outside the brain to cause analgesia pointing to a new target for pain relief that may have fewer risks and side effects Full Text Epidermal Growth Factor Receptor Not Just Epidermal By Alexei Morozov Science Translational Medicine 20 Oct 2010 54ec163 Inhibition of epidermal growth factor receptor enhances granulocyte colony stimulating factor induced mobilization of hematopoietic stem and progenitor cells Full Text Stop Poking Me New Implantable Microbeads for Continuous Glucose Monitoring By Kenneth W Ng Science Translational Medicine 20 Oct 2010 54ec164 New implantable microbeads offer a minimally invasive alternative to finger pricks for glucose monitoring Full Text More From Science Translational Medicine Current Table of Contents Archive In the

    Original URL path: http://stm.sciencemag.org/content/2/54 (2016-02-10)
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  • Table of Contents — October 27, 2010, 2 (55) | Science Translational Medicine
    Rachel L Atkinson Mei Zhang Parmeswaran Diagaradjane Sirisha Peddibhotla Alejandro Contreras Susan G Hilsenbeck Wendy A Woodward Sunil Krishnan Jenny C Chang Jeffrey M Rosen Science Translational Medicine 27 Oct 2010 55ra79 Local hyperthermia with gold nanoshells sensitizes cancer stem cells to radiation treatment in mouse and human breast cancer preclinical models Editor s Summary Abstract Full Text PDF Editors Choice An Expanded Tumor Playing Field By Joshi Alumkal Science Translational Medicine 27 Oct 2010 55ec165 Tumors promote DNA damage at distant sites by boosting chronic inflammation Full Text Why Do You Like Fat and Sugar Ask Your Mom By Rhonda Bentley Lewis Science Translational Medicine 27 Oct 2010 55ec166 A high fat high sugar diet in female mice promotes a preference for a similar diet and epigenetic changes in her offspring Full Text A Flexible Analysis of Gene Environment Interactions By Nichole Carlson Science Translational Medicine 27 Oct 2010 55ec167 Bayesian analysis of gene environment interplay offers a way to better balance case only and case control strategies Full Text Licensed to Enter By Elaine Cheng Science Translational Medicine 27 Oct 2010 55ec168 A protein transduction domain peptide enhances the cellular uptake of Foxp3 protein for the treatment of autoimmune and allergic disorders Full Text Erratum A Correction to the Research Article Titled Reversal of Depressed Behaviors in Mice by p11 Gene Therapy in the Nucleus Accumbens by Brian Alexander Jennifer Warner Schmidt Therese Eriksson Carol Tamminga Margarita Arango Llievano Subroto Ghose Mary Vernov Mihaela Stavarche Sergei Musatov Marc Flajolet Per Svenningsson Paul Greengard Michael G Kaplitt Science Translational Medicine 27 Oct 2010 55er3 Full Text PDF More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers

    Original URL path: http://stm.sciencemag.org/content/2/55 (2016-02-10)
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  • Table of Contents — November 03, 2010, 2 (56) | Science Translational Medicine
    Langmade Vasumathi Molugu Sarah E Gale Dana Olzeski Rohini Sidhu Dennis J Dietzen Rao Fu Christopher A Wassif Nicole M Yanjanin Steven P Marso John House Charles Vite Jean E Schaffer Daniel S Ory Science Translational Medicine 03 Nov 2010 56ra81 Oxysterols are biomarkers for diagnosis and drug treatment in Niemann Pick C1 disease Editor s Summary Abstract Full Text PDF Review Mathematical Modeling of Molecular Data in Translational Medicine Theoretical Considerations By Nicholas F Marko Robert J Weil Science Translational Medicine 03 Nov 2010 56rv4 Appropriate data modeling strategies must be used when analyses generate tens of thousands of data points from individual study participants Editor s Summary Abstract Full Text PDF Editors Choice Metabolic Syndrome Pass It On By Andrew A Bremer Science Translational Medicine 03 Nov 2010 56ec169 Overnutrition in neonatal males may yield epigenetic changes that specify adverse metabolic phenotypes in subsequent generations Full Text Stopping the Drilling and the Filling Regenerating Teeth with Soluble Human Tooth Proteins By Kenneth W Ng Science Translational Medicine 03 Nov 2010 56ec170 New research into human tooth proteins may lead to ways to regenerate tooth structures and treat tooth decay Full Text Exomes Take Center Stage By Samir Damani Science Translational Medicine 03 Nov 2010 56ec171 Sequencing exomes identifies a new gene variant causing familial combined hypolipidemia Full Text The New Dish on Fish By Donna E Hansel Science Translational Medicine 03 Nov 2010 56ec172 In spite of its beneficial reputation fish oil may promote colon cancer in mice with chronic colitis by decreasing immune function Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe Submit About The Cover ONLINE

    Original URL path: http://stm.sciencemag.org/content/2/56 (2016-02-10)
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  • Table of Contents — November 10, 2010, 2 (57) | Science Translational Medicine
    A Schaller Beatrice Waters Gabor Jarai John Westwick Steven L Kunkel Fernando J Martinez Cory M Hogaboam Science Translational Medicine 10 Nov 2010 57ra82 Compared to slow progressors patients with rapidly progressive idiopathic pulmonary fibrosis express more TLR9 which recognizes unmethylated CpG DNA and stimulates the fibrotic process Editor s Summary Abstract Full Text PDF Prevention of Muscle Aging by Myofiber Associated Satellite Cell Transplantation By John K Hall Glen B Banks Jeffrey S Chamberlain Bradley B Olwin Science Translational Medicine 10 Nov 2010 57ra83 Transplantation of myofibers and associated stem cells into injured muscle protects against age related muscle degeneration in mice Editor s Summary Abstract Full Text PDF Editors Choice Breathe Bitter Breathe Easy By Shama Ahmad Science Translational Medicine 10 Nov 2010 57ec173 Bitter taste receptors in lungs might help relax asthmatic airways Full Text New Cellular Culprits in Gaucher s Disease By Christoph Buettner Science Translational Medicine 10 Nov 2010 57ec174 Gaucher s disease is caused by defects in osteoblasts dendritic cells and T cells as well as macrophages Full Text The Virus in the Machine By Michael J Minzenberg Science Translational Medicine 10 Nov 2010 57ec175 HIV interferes with dopamine function in the brain s subcortical motor system explaining some of its neurological effects Full Text Attacking Lung Cancer One Mutation at a Time By Alexei Morozov Science Translational Medicine 10 Nov 2010 57ec176 Lung cancers that carry the EML4 ALK translocation are uniquely sensitive to an ALK inhibitor Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe Submit About The Cover ONLINE COVER Twice Transplanted Muscles A cross section of fibers from a mouse tibialis

    Original URL path: http://stm.sciencemag.org/content/2/57 (2016-02-10)
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