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  • Table of Contents — January 19, 2011, 3 (66) | Science Translational Medicine
    dual function aptamer that targets both a HIV 1 surface protein and a critical messenger RNA can inhibit HIV infection in humanized mice Editor s Summary Abstract Full Text PDF Editors Choice Novel Peptide to Treat Sepsis Induced Acute Lung Injury By Shama Ahmad Science Translational Medicine 19 Jan 2011 66ec7 Inhibition of protein kinase C δ activity limits acute respiratory distress syndrome related lung injury Full Text Excited to Madness By Michael J Minzenberg Science Translational Medicine 19 Jan 2011 66ec8 Faltering inhibitory interneurons in the prefrontal cortex lead to chaos in the schizophrenia brain Full Text Catastrophe in the Nucleus By Alexei Morozov Science Translational Medicine 19 Jan 2011 66ec9 Some cancers carry massive genomic rearrangements confined to one chromosomal region that are thought to arise in a single event Full Text Erratum A Correction to the Research Article Titled Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer by J Weiss M L Sos D Seidel M Peifer T Zander J M Heuckmann R T Ullrich R Menon S Maier A Soltermann H Moch P Wagener F Fischer S Heynck M Koker J Schöttle F Leenders F Gabler I Dabow S Querings L C Heukamp H Balke Want S Ansén D Rauh I Baessmann J Altmüller Z Wainer M Conron G Wright P Russell B Solomon E Brambilla C Brambilla P Lorimier S Sollberg O T Brustugun W Engel Riedel C Ludwig I Petersen J Sänger J Clement H Groen W Timens H Sietsma E Thunnissen E Smit D Heideman F Cappuzzo C Ligorio S Damiani M Hallek R Beroukhim W Pao B Klebl M Baumann R Buettner K Ernestus E Stoelben J Wolf P Nürnberg S Perner R K Thomas Science Translational Medicine 19 Jan 2011 66er2 Full Text

    Original URL path: http://stm.sciencemag.org/content/3/66 (2016-02-10)
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  • Table of Contents — January 26, 2011, 3 (67) | Science Translational Medicine
    P Liu Daniel Durocher Benjamin G Neel Brian O Sullivan Bernard Cummings Rob Bristow Jeff Wrana Fei Fei Liu Science Translational Medicine 26 Jan 2011 67ra7 Uroporphyrinogen decarboxylase inhibition sensitizes head and neck cancer to both radiotherapy and chemotherapy Editor s Summary Abstract Full Text PDF Manipulating the Bioenergetics of Alloreactive T Cells Causes Their Selective Apoptosis and Arrests Graft Versus Host Disease By Erin Gatza Daniel R Wahl Anthony W Opipari Thomas B Sundberg Pavan Reddy Chen Liu Gary D Glick James L M Ferrara Science Translational Medicine 26 Jan 2011 67ra8 Bioenergetic properties differentiate alloreactive T cells from other proliferating cells and can be exploited to arrest GVHD in mice Editor s Summary Abstract Full Text PDF Editors Choice An Epigenetic Road to Genome Instability By Joshi Alumkal Science Translational Medicine 26 Jan 2011 67ec10 The histone methyltransferase EZH2 promotes genomic instability and oncogenic signaling in putative breast cancer stem cells Full Text Yet Another Reason Rats Don t Take Day Jobs By Rhonda Bentley Lewis Science Translational Medicine 26 Jan 2011 67ec11 Feeding rats during the day rather than during their normal night pattern promotes obesity Full Text Bacterial Breakaway By Elaine Cheng Science Translational Medicine 26 Jan 2011 67ec12 Peptides produced by Staphylococcus epidermidis promote dissemination of this bacterium from biofilms leading to systemic infection in catheterized patients Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe Submit About The Cover ONLINE COVER A Cancer Bull s Eye The image shows the accumulation of porphyrin red in head and neck cancer cells nucleus blue mitochondria green after down regulation of a key heme biosynthetic enzyme This enzyme

    Original URL path: http://stm.sciencemag.org/content/3/67 (2016-02-10)
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  • Table of Contents — February 02, 2011, 3 (68) | Science Translational Medicine
    Science Translational Medicine 02 Feb 2011 68ra9 Nonimmunogenic tissue engineered vascular grafts stored long term maintain their patency strength and function after transplant in large animal models Editor s Summary Abstract Full Text PDF Human CD3 Transgenic Mice Preclinical Testing of Antibodies Promoting Immune Tolerance By Chantal Kuhn Sylvaine You Fabrice Valette Geoff Hale Peter van Endert Jean François Bach Herman Waldmann Lucienne Chatenoud Science Translational Medicine 02 Feb 2011 68ra10 Human CD3 transgenic mice offer a unique preclinical tool to test drugs promoting immune tolerance Editor s Summary Abstract Full Text PDF Editors Choice Estrogen and Energy Balance By Andrew A Bremer Science Translational Medicine 02 Feb 2011 68ec13 Nonclassical estrogen signaling mediates estrogen s effect on metabolism Full Text Adiponectin Battles Ceramides By Christoph Buettner Science Translational Medicine 02 Feb 2011 68ec14 The beneficial effects of adiponectin are mediated through the ceramidase activity of its receptor Full Text Going With the Flow By Kenneth W Ng Science Translational Medicine 02 Feb 2011 68ec15 Prolonged growth factor delivery using a hydrogel improves blood vessel formation in the heart Full Text Podcast Science Translational Medicine Podcast 2 February 2011 By Shannon Dahl Orla Smith Science Translational Medicine 02 Feb 2011 68pc2 A conversation with Shannon Dahl about how to bioengineer off the shelf vascular grafts for use in surgical transplantation Abstract More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe Submit About The Cover ONLINE COVER From One Many Surgical transplantation of vascular grafts is required for coronary artery bypass in heart attack patients or to provide access for dialysis for kidney disease patients Dahl and colleagues have developed a method to bioengineer

    Original URL path: http://stm.sciencemag.org/content/3/68 (2016-02-10)
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  • Table of Contents — February 09, 2011, 3 (69) | Science Translational Medicine
    and Intralymphatic Cancer Cells Prevents Metastasis By Tuomas Tammela Anne Saaristo Tanja Holopainen Seppo Ylä Herttuala Leif C Andersson Susanna Virolainen Ilkka Immonen Kari Alitalo Science Translational Medicine 09 Feb 2011 69ra11 Destruction of lymphatic vessels by photodynamic therapy suppresses metastasis by eradicating both the in transit tumor cells and their conduit to distant tissues Editor s Summary Abstract Full Text PDF 5 Lipoxygenase Metabolite 4 HDHA Is a Mediator of the Antiangiogenic Effect of ω 3 Polyunsaturated Fatty Acids By Przemyslaw Sapieha Andreas Stahl Jing Chen Molly R Seaward Keirnan L Willett Nathan M Krah Roberta J Dennison Kip M Connor Christopher M Aderman Elvira Liclican Arianna Carughi Dalia Perelman Yoshihide Kanaoka John Paul SanGiovanni Karsten Gronert Lois E H Smith Science Translational Medicine 09 Feb 2011 69ra12 In mice ω 3 fatty acids in the diet are converted by 5 lipoxygenase to a metabolite that inhibits destructive vessel growth similar to diabetic retinopathy Editor s Summary Abstract Full Text PDF Editors Choice Genetic Testing Exonerated By Samir Damani Science Translational Medicine 09 Feb 2011 69ec16 The risks associated with direct to consumer genetic testing appear to be minimal Full Text Targeting Melanoma Endothelin B Receptor Makes an Encore By Donna E Hansel Science Translational Medicine 09 Feb 2011 69ec17 An antibody to the endothelin B receptor coupled to an antimitotic agent can shrink melanoma in vitro and in mouse models Full Text Genie in a Bottle By Alexei Morozov Science Translational Medicine 09 Feb 2011 69ec18 Adaptive cell transfer shows efficacy in synovial sarcoma and melanoma Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe Submit About The Cover

    Original URL path: http://stm.sciencemag.org/content/3/69 (2016-02-10)
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  • Table of Contents — February 16, 2011, 3 (70) | Science Translational Medicine
    diabetes complications possibly because of high resistance to oxidative damage and low circulating insulin Editor s Summary Abstract Full Text PDF The Effect of Treatment Expectation on Drug Efficacy Imaging the Analgesic Benefit of the Opioid Remifentanil By Ulrike Bingel Vishvarani Wanigasekera Katja Wiech Roisin Ni Mhuircheartaigh Michael C Lee Markus Ploner Irene Tracey Science Translational Medicine 16 Feb 2011 70ra14 An individual s expectation that a pain treatment will or will not work can alter both its subjective effectiveness and the pain related activity in the brain Editor s Summary Abstract Full Text PDF Editors Choice Stem Cell Therapy Works in Mice Models of Emphysema By Shama Ahmad Science Translational Medicine 16 Feb 2011 70ec19 Autologous adipose derived stem cells attenuate both pulmonary and extrapulmonary effects of cigarette smoke exposure Full Text Growth Factor Makes Memories Stick By Christoph Buettner Science Translational Medicine 16 Feb 2011 70ec20 Insulin like growth factor II forestalls forgetting by boosting long term potentiation and memory retention Full Text Shining a Light on Stroke By Michael J Minzenberg Science Translational Medicine 16 Feb 2011 70ec21 In vivo mouse model yields unique insights into brain responses to stroke Full Text Letter Comment on Multidimensional Results Reporting to Participants in Genomic Studies Getting It Right By Ebony B Bookman Aleisha A Langehorne John H Eckfeldt Kathleen C Glass Gail P Jarvik Michael Klag Greg Koski Arno Motulsky Benjamin Wilfond Teri A Manolio Richard R Fabsitz Russell V Luepker Science Translational Medicine 16 Feb 2011 70le1 The Commentary by Kohane and Taylor published on 23 June 2010 mistakenly indicates that the NHLBI Working Group advocated that researchers keep genetic information from research subjects if an intervention is not available for the disease Editor s Summary Abstract Full Text PDF More From Science Translational Medicine Current Table of

    Original URL path: http://stm.sciencemag.org/content/3/70 (2016-02-10)
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  • Table of Contents — February 23, 2011, 3 (71) | Science Translational Medicine
    nevi and could enhance current clinical diagnostic protocols Editor s Summary Abstract Full Text PDF Micro NMR for Rapid Molecular Analysis of Human Tumor Samples By Jered B Haun Cesar M Castro Rui Wang Vanessa M Peterson Brett S Marinelli Hakho Lee Ralph Weissleder Science Translational Medicine 23 Feb 2011 71ra16 A portable micro NMR device enables rapid molecular diagnosis from scarce cancer cells in fine needle aspirates from human tumors Editor s Summary Abstract Full Text PDF Editors Choice It Just Keeps Going and Going By Angela Colmone Science Translational Medicine 23 Feb 2011 71ec22 Mutations in a superoxide forming enzyme lead to macrophage specific defects and predispose to mycobacterium infection Full Text It s a FAKt Kinase Mediates Metastasis By Megan L Frisk Science Translational Medicine 23 Feb 2011 71ec23 Metastatic cancer cells lodge in lung as a result of endothelial cell kinase activity Full Text Stemming Hair Loss By Kelly LaMarco Science Translational Medicine 23 Feb 2011 71ec24 Hair follicles from men with male pattern baldness retain quiescent stem like cells but not progenitor cells suggesting that the condition may be reversible Full Text Podcast Science Translational Medicine Podcast 23 February 2011 By Ralph Weissleder Orla Smith Science Translational Medicine 23 Feb 2011 71pc3 A conversation with Ralph Weissleder about his smart phone operated micro NMR device that provides accurate cancer diagnoses in 60 minutes Abstract More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information for Reviewers Staff Contact Us Subscribe Submit About The Cover ONLINE COVER When Small Meets Smart A miniaturized nuclear magnetic resonance NMR device detects scarce cancer cells in tissue biopsies with speed and accuracy reported by Haun et al in this

    Original URL path: http://stm.sciencemag.org/content/3/71 (2016-02-10)
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  • Table of Contents — March 02, 2011, 3 (72) | Science Translational Medicine
    02 Mar 2011 72ra17 SPINK1 is a therapeutic target in a subset of patients with SPINK1 ETS prostate cancer Editor s Summary Abstract Full Text PDF Antisense Oligonucleotides Delivered to the Mouse CNS Ameliorate Symptoms of Severe Spinal Muscular Atrophy By Marco A Passini Jie Bu Amy M Richards Cathrine Kinnecom S Pablo Sardi Lisa M Stanek Yimin Hua Frank Rigo John Matson Gene Hung Edward M Kaye Lamya S Shihabuddin Adrian R Krainer C Frank Bennett Seng H Cheng Science Translational Medicine 02 Mar 2011 72ra18 Central nervous system directed antisense therapy ameliorates symptoms in a severe neuromuscular disorder in mice Editor s Summary Abstract Full Text PDF Editors Choice Expert Network By Kelly LaMarco Science Translational Medicine 02 Mar 2011 72ec25 Meet Science Translational Medicine s new Associate Scientific Advisors for 2011 Full Text Coronary Artery Disease Decoded By Samir Damani Science Translational Medicine 02 Mar 2011 72ec26 The p21 region of chromosome 9 modulates inflammatory responses in coronary artery disease Full Text A Sweet Spot for Kallikrein in Intracerebral Hemorrhage By Carmella Evans Molina Science Translational Medicine 02 Mar 2011 72ec27 Hyperglycemia exacerbates hemorrhagic stroke through plasma kallikrein induced inhibition of platelet aggregation Full Text Toward the Future of Personalized Medicine By Richard J Lin Science Translational Medicine 02 Mar 2011 72ec28 NF κB inhibitor α in combination with MGMT status may help contribute to personalized treatments for glioblastoma multiforme Full Text These Peptides Have Got a Lot of Nerve By Christopher L Skelly Science Translational Medicine 02 Mar 2011 72ec29 Short fluorescently labeled peptides could allow for better visualization of peripheral nerves during surgery Full Text More From Science Translational Medicine Current Table of Contents Archive In the Pipeline About Science Translational Medicine Mission and Scope Editors and Advisory Boards Editorial Policies Information for Authors Information

    Original URL path: http://stm.sciencemag.org/content/3/72 (2016-02-10)
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  • Table of Contents — March 09, 2011, 3 (73) | Science Translational Medicine
    09 Mar 2011 73ra19 In systemic lupus erythematosus neutrophils release peptide self DNA complexes that trigger plasmacytoid dendritic cell activation and autoantibody formation Editor s Summary Abstract Full Text PDF Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus By Gina S Garcia Romo Simone Caielli Barbara Vega John Connolly Florence Allantaz Zhaohui Xu Marilynn Punaro Jeanine Baisch Cristiana Guiducci Robert L Coffman Franck J Barrat Jacques Banchereau Virginia Pascual Science Translational Medicine 09 Mar 2011 73ra20 In systemic lupus erythematosus neutrophil extracellular traps activate plasmacytoid dendritic cells to produce type I interferon Editor s Summary Abstract Full Text PDF Nanodiamond Therapeutic Delivery Agents Mediate Enhanced Chemoresistant Tumor Treatment By Edward K Chow Xue Qing Zhang Mark Chen Robert Lam Erik Robinson Houjin Huang Daniel Schaffer Eiji Osawa Andrei Goga Dean Ho Science Translational Medicine 09 Mar 2011 73ra21 Nanodiamond based drug delivery significantly enhanced treatment efficacy and safety in multiple chemoresistant cancer models Editor s Summary Abstract Full Text PDF Editors Choice Bones Break the News on Reproduction By Mickie H Cheng Science Translational Medicine 09 Mar 2011 73ec30 Osteocalcin produced by bone regulates testosterone production and male fertility Full Text This Changes Everything Twice By David S Hong Science Translational Medicine 09 Mar 2011 73ec31 Two small molecule drugs that target the mTOR and VEGF PDGF pathways are highly effective in treating pancreatic neuroendocrine tumors Full Text Target Practice By Melissa Nyendak Science Translational Medicine 09 Mar 2011 73ec32 An inhibitor of RNA degradation inhibits growth of drug resistant Staphylococcus aureus pinpointing a new process for antibacterial targeting Full Text Enabling Technology Gives the Brain a Hand By Wei Wang Science Translational Medicine 09 Mar 2011 73ec33 Electrocorticographic signals enable brain computer communication in a paralyzed stroke patient Full Text More From

    Original URL path: http://stm.sciencemag.org/content/3/73 (2016-02-10)
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