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  • Table of Contents — January 15, 2014, 6 (219) | Science Translational Medicine
    MARCO on inflammatory monocytes resulting in their apoptosis and reduced inflammatory damage in a range of diseases Editor s Summary Abstract Full Text PDF Human T H 9 Cells Are Skin Tropic and Have Autocrine and Paracrine Proinflammatory Capacity By Christoph Schlapbach Ahmed Gehad Chao Yang Rei Watanabe Emmanuella Guenova Jessica E Teague Laura Campbell Nikhil Yawalkar Thomas S Kupper Rachael A Clark Science Translational Medicine 15 Jan 2014 219ra8 Aberrant activation of human T H 9 cells may contribute to inflammatory diseases of the skin Editor s Summary Abstract Full Text PDF Cancer Cell Profiling by Barcoding Allows Multiplexed Protein Analysis in Fine Needle Aspirates By Adeeti V Ullal Vanessa Peterson Sarit S Agasti Suan Tuang Dejan Juric Cesar M Castro Ralph Weissleder Science Translational Medicine 15 Jan 2014 219ra9 Barcoding technology enabled measurement of hundreds of cellular proteins from cancer patients with single cell resolution Editor s Summary Abstract Full Text PDF Editors Choice Breathe Easy But Be Concerned By William J Mack Science Translational Medicine 15 Jan 2014 219ec10 Exposure to particulate pollution is associated with increased mortality Full Text RIG ging Biomarkers for Therapeutic Response By Trudy G Oliver Science Translational Medicine 15 Jan 2014 219ec11 Hepatic RIG I is a biomarker for survival and response to interferon α treatment in hepatocellular carcinoma Full Text Releasing the Brake Drives Fear Behavior By Vikaas S Sohal Science Translational Medicine 15 Jan 2014 219ec12 Conditioned stimuli inhibit parvalbumin interneurons in the prefrontal cortex leading to changes in prefrontal oscillations and output that drive conditioned fear behavior Full Text Important Job for a Nervous Glucose Transporter By Amir Tirosh Science Translational Medicine 15 Jan 2014 219ec13 Maintaining normal pancreatic β cell mass and function is regulated by the glucose transporter Glut2 in the nervous system Full Text Letter Comment

    Original URL path: http://stm.sciencemag.org/content/6/219 (2016-02-10)
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  • Table of Contents — January 22, 2014, 6 (220) | Science Translational Medicine
    Mavilio Philippe Moullier Alan H Beggs Anna Buj Bello Science Translational Medicine 22 Jan 2014 220ra10 Intravenous injection of an adeno associated viral vector expressing the myotubularin MTM1 gene improves survival and rescues skeletal muscle function in mice and dogs affected by myotubular myopathy Editor s Summary Abstract Full Text PDF Identifying Gut Microbe Host Phenotype Relationships Using Combinatorial Communities in Gnotobiotic Mice By Jeremiah J Faith Philip P Ahern Vanessa K Ridaura Jiye Cheng Jeffrey I Gordon Science Translational Medicine 22 Jan 2014 220ra11 Identifying human gut bacterial strains that affect three diverse biological responses should facilitate discovery of next generation probiotics and realization of the microbiota s diagnostic potential Editor s Summary Abstract Full Text PDF Neonatal Estradiol Stimulation Prevents Epilepsy in Arx Model of X Linked Infantile Spasms Syndrome By Pedro R Olivetti Atul Maheshwari Jeffrey L Noebels Science Translational Medicine 22 Jan 2014 220ra12 Estradiol treatment of a mouse model of X linked infantile spasms syndrome during the neonatal period prevents epilepsy in adulthood restores interneurons and alters mRNA levels of Arx targets Editor s Summary Abstract Full Text PDF Editors Choice Giving Leptin a Second Chance By Ania M Jastreboff Science Translational Medicine 22 Jan 2014 220ec14 GLP 1 glucagon co agonist may help restore leptin responsiveness in diet induced obese mice that remain on a high fat diet Full Text Friendly Bacteria By Erkin Seker Science Translational Medicine 22 Jan 2014 220ec15 Engineered bacterial membrane vesicles target cancer cells and deliver small interfering RNA to halt tumor growth Full Text A Metabolic Relic By Benjamin F Voight Science Translational Medicine 22 Jan 2014 220ec16 A risk haplotype common among Mexican and Latin American people implicates triacylglycerol metabolism in susceptibility to type 2 diabetes Full Text More From Science Translational Medicine Current Table of Contents

    Original URL path: http://stm.sciencemag.org/content/6/220 (2016-02-10)
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  • Table of Contents — January 29, 2014, 6 (221) | Science Translational Medicine
    Meuli Ernst Reichmann Science Translational Medicine 29 Jan 2014 221ra14 Human lymphatic capillaries were engineered in a 3D hydrogel system to improve dermo epidermal skin grafting Editor s Summary Abstract Full Text PDF Antioxidants Accelerate Lung Cancer Progression in Mice By Volkan I Sayin Mohamed X Ibrahim Erik Larsson Jonas A Nilsson Per Lindahl Martin O Bergo Science Translational Medicine 29 Jan 2014 221ra15 The antioxidants acetylcysteine and vitamin E accelerate tumor progression and reduce survival in mouse models of lung cancer by disrupting the ROS p53 axis Editor s Summary Abstract Full Text PDF Editors Choice Regenerative Medicine Gets Vocal By Mercedes Balcells Science Translational Medicine 29 Jan 2014 221ec17 An acellular scaffold derived from urinary bladder extracellular matrix is able to regenerate a functional larynx Full Text TRAIL Blazing Therapy Against Circulating Tumor Cells By Edward Kai Hua Chow Science Translational Medicine 29 Jan 2014 221ec18 Nanoparticle mediated functionalization of leukocytes is effective against circulating tumor cells Full Text A Simple Solution for a Big Problem By Mustafa Mahfuz Science Translational Medicine 29 Jan 2014 221ec19 A randomized controlled trial shows improved gut villous morphology in patients with environmentally induced enteropathy given high dose micronutrient supplements Full Text Moving from Unknown Unknown to Known Unknown By Adam A Margolin Science Translational Medicine 29 Jan 2014 221ec20 Genomic analysis of nearly 5000 tumors demonstrates that we are far from finding all the cancer genes Full Text Shiva the Destroyer Targeting the Destruction of RNA Polymerase for Cancer Treatment By Goutham Narla Science Translational Medicine 29 Jan 2014 221ec21 A new drug with a unique mechanism of action intercalates into GC rich ribosomal DNA blocking RNA polymerase I and inhibiting tumor growth Full Text It s ARAP for Type II Diabetes By Benjamin M Neale Science Translational Medicine 29 Jan

    Original URL path: http://stm.sciencemag.org/content/6/221 (2016-02-10)
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  • Table of Contents — February 05, 2014, 6 (222) | Science Translational Medicine
    Translational Medicine 05 Feb 2014 222ra17 Blocking the enzyme that initiates the intrinsic coagulation pathway protects against thrombosis in bypass systems and does not cause excess bleeding in vivo Editor s Summary Abstract Full Text PDF High Dose Parenteral Ascorbate Enhanced Chemosensitivity of Ovarian Cancer and Reduced Toxicity of Chemotherapy By Yan Ma Julia Chapman Mark Levine Kishore Polireddy Jeanne Drisko Qi Chen Science Translational Medicine 05 Feb 2014 222ra18 Pharmacological use of ascorbate vitamin C enhanced chemosensitivity of ovarian cancer in preclinical models and reduced chemotherapy associated toxicity in patients Editor s Summary Abstract Full Text PDF Restoring Natural Sensory Feedback in Real Time Bidirectional Hand Prostheses By Stanisa Raspopovic Marco Capogrosso Francesco Maria Petrini Marco Bonizzato Jacopo Rigosa Giovanni Di Pino Jacopo Carpaneto Marco Controzzi Tim Boretius Eduardo Fernandez Giuseppe Granata Calogero Maria Oddo Luca Citi Anna Lisa Ciancio Christian Cipriani Maria Chiara Carrozza Winnie Jensen Eugenio Guglielmelli Thomas Stieglitz Paolo Maria Rossini Silvestro Micera Science Translational Medicine 05 Feb 2014 222ra19 A multigrasp bidirectional hand prosthesis delivers dynamic sensory feedback allowing a user with a hand amputation to achieve fine grasping force control and realistic object sensing Editor s Summary Abstract Full Text PDF Editors Choice Diabetes DNA Methylation and in Utero Environment By Egle Bytautiene Science Translational Medicine 05 Feb 2014 222ec23 Exposure to a diabetic in utero environment alters the methylation of genes associated with diabetes and Notch signaling in Pima Indian subjects Full Text Schizophrenia at the Synapse By Christopher Gregg Science Translational Medicine 05 Feb 2014 222ec24 Proteins that power excitatory synapses are mutated in schizophrenia Full Text How Much Do Drugs Matter By Anandi N Sheth Science Translational Medicine 05 Feb 2014 222ec25 Drugs penetrate poorly into the lymphatic tissues which are sites of persistent HIV replication Full Text PREDICTing the Era

    Original URL path: http://stm.sciencemag.org/content/6/222 (2016-02-10)
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  • Table of Contents — February 12, 2014, 6 (223) | Science Translational Medicine
    Heather Doviak Jason W O Neill James A Shuman Craig P Novack Kia N Zellars Sara Pettaway Roy A Black Aarif Khakoo TaeWeon Lee Rupak Mukherjee Joseph H Gorman Robert C Gorman Jason A Burdick Francis G Spinale Science Translational Medicine 12 Feb 2014 223ra21 Delivery of a hydrogel providing sustained release of recombinant TIMP 3 attenuated adverse ventricular remodeling after myocardial infarction in pigs Editor s Summary Abstract Full Text PDF Integrative Biology Approach Identifies Cytokine Targeting Strategies for Psoriasis By Gayathri K Perera Chrysanthi Ainali Ekaterina Semenova Christian Hundhausen Guillermo Barinaga Deepika Kassen Andrew E Williams Muddassar M Mirza Mercedesz Balazs Xiaoting Wang Robert Sanchez Rodriguez Andrej Alendar Jonathan Barker Sophia Tsoka Wenjun Ouyang Frank O Nestle Science Translational Medicine 12 Feb 2014 223ra22 The serine threonine kinase PIM1 is a critical checkpoint for human skin inflammation and potential target in psoriasis Editor s Summary Abstract Full Text PDF CXCL10 Is Critical for the Progression and Maintenance of Depigmentation in a Mouse Model of Vitiligo By Mehdi Rashighi Priti Agarwal Jillian M Richmond Tajie H Harris Karen Dresser Ming Wan Su Youwen Zhou April Deng Christopher A Hunter Andrew D Luster John E Harris Science Translational Medicine 12 Feb 2014 223ra23 Neutralizing CXCL10 reverses established vitiligo Editor s Summary Abstract Full Text PDF Editors Choice Golden Cage for Triggered Release By Natalie Artzi Science Translational Medicine 12 Feb 2014 223ec27 Reservoir capped with an externally tunable porous membrane enables light triggered release of drugs Full Text Neutrophils Another Case of Wrongful Conviction By Christopher R Polage Science Translational Medicine 12 Feb 2014 223ec28 Oxygen depletion by the neutrophil respiratory burst induces a protective stress response in mucosal epithelial cells Full Text Cooking Tips for Pluripotency Add Acid and Squeeze By Anne Schaefer Science Translational Medicine 12 Feb 2014

    Original URL path: http://stm.sciencemag.org/content/6/223 (2016-02-10)
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  • Table of Contents — February 26, 2014, 6 (225) | Science Translational Medicine
    Amy K Sawtell Bashar Hamza Joseph Willson Sarah R Walmsley Sean R Anderson Mark C Coles Stuart N Farrow Roberto Solari Simon Jones Lynne R Prince Daniel Irimia G Ed Rainger Visakan Kadirkamanathan Moira K B Whyte Stephen A Renshaw Science Translational Medicine 26 Feb 2014 225ra29 The proresolution therapeutic tanshinone IIA drives inflammation resolution by reverse migration Editor s Summary Abstract Full Text PDF Reports Targeting miR 21 to Treat Psoriasis By Juan Guinea Viniegra María Jiménez Helia B Schonthaler Raquel Navarro Yolanda Delgado María José Concha Garzón Erwin Tschachler Susanna Obad Esteban Daudén Erwin F Wagner Science Translational Medicine 26 Feb 2014 225re1 Targeting miR 21 may be a new way to treat psoriasis Editor s Summary Abstract Full Text PDF Editors Choice Carotid Stenting What Have You Done for Me Lately By William J Mack Science Translational Medicine 26 Feb 2014 225ec35 Patient outcomes after carotid stenting are associated with the number of recent procedures a surgeon has performed Full Text Bosom Buddies Close Connections Between Breast and Bladder Cancer By Trudy G Oliver Science Translational Medicine 26 Feb 2014 225ec36 Gene expression profiling of advanced bladder cancer identifies molecular subtypes highly reminiscent of subtypes found in breast cancer Full Text You Have Your Father s Nose By Vikaas S Sohal Science Translational Medicine 26 Feb 2014 225ec37 After a male mouse has an aversive experience with a particular odor its sperm transmit an increased sensitivity for that odor to subsequent generations Full Text Growing Bigger in Kindergarten By Amir Tirosh Science Translational Medicine 26 Feb 2014 225ec38 The highest incidence rate of childhood obesity occurs during kindergarten Full Text Erratum A Correction to the Research Article Titled Structural Biochemical and Clinical Characterization of Epidermal Growth Factor Receptor EGFR Exon 20 Insertion Mutations in Lung Cancer by

    Original URL path: http://stm.sciencemag.org/content/6/225 (2016-02-10)
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  • Table of Contents — March 05, 2014, 6 (226) | Science Translational Medicine
    later stages of autosomal dominant Alzheimer s disease Editor s Summary Abstract Full Text PDF Angiophagy Prevents Early Embolus Washout But Recanalizes Microvessels Through Embolus Extravasation By Jaime Grutzendler Sasidhar Murikinati Bennett Hiner Lingling Ji Carson K Lam Taehwan Yoo Shobhana Gupta Brian P Hafler Ron A Adelman Peng Yuan Guadalupe Rodriguez Science Translational Medicine 05 Mar 2014 226ra31 Endothelial engulfment of emboli angiophagy occurs in microvascular beds throughout the body resulting in emboli extravasation and vessel recanalization Editor s Summary Abstract Full Text PDF Localized Oncolytic Virotherapy Overcomes Systemic Tumor Resistance to Immune Checkpoint Blockade Immunotherapy By Dmitriy Zamarin Rikke B Holmgaard Sumit K Subudhi Joon Seok Park Mena Mansour Peter Palese Taha Merghoub Jedd D Wolchok James P Allison Science Translational Medicine 05 Mar 2014 226ra32 Intratumoral treatment with an oncolytic virus results in inflammatory infiltrates in distant tumors and sensitizes the tumors to immune mediated rejection in the setting of immunotherapy with CTLA 4 blocking antibodies Editor s Summary Abstract Full Text PDF Editors Choice Insulin Food for Thought By Ania M Jastreboff Science Translational Medicine 05 Mar 2014 226ec39 Intranasal insulin improves cognitive function in individuals with type 2 diabetes Full Text To Catch a Pre Leukemia By Adam A Margolin Science Translational Medicine 05 Mar 2014 226ec40 DNMT3A mutations occur in pre leukemic hematopoietic stem cells and define early stage events in the progression to acute myeloid leukemia Full Text Taking the Fight Outside By Erkin Seker Science Translational Medicine 05 Mar 2014 226ec41 Engineered miniature wells connected to biomimetic paths attract cancer cells away from the tumor site for eradication Full Text SORT ing Out That Pesky Cholesterol By Benjamin F Voight Science Translational Medicine 05 Mar 2014 226ec42 SORT1 interacts with PCSK9 to facilitate its secretion from the liver which regulates levels of

    Original URL path: http://stm.sciencemag.org/content/6/226 (2016-02-10)
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  • Table of Contents — March 12, 2014, 6 (227) | Science Translational Medicine
    Abboud Waleed Al Herz Irina Kondratenko László Maródi Hanno Glimm Brigitte Schlegelberger Axel Schambach Michael Heinrich Albert Manfred Schmidt Christof von Kalle Christoph Klein Science Translational Medicine 12 Mar 2014 227ra33 Wiskott Aldrich syndrome gene therapy is feasible but γ retroviral vectors contribute a substantial risk of leukemogenesis Editor s Summary Abstract Full Text PDF TGF β Signaling Mediates Endothelial to Mesenchymal Transition EndMT During Vein Graft Remodeling By Brian C Cooley Jose Nevado Jason Mellad Dan Yang Cynthia St Hilaire Alejandra Negro Fang Fang Guibin Chen Hong San Avram D Walts Robin L Schwartzbeck Brandi Taylor Jan D Lanzer Andrew Wragg Abdalla Elagha Leilani E Beltran Colin Berry Robert Feil Renu Virmani Elena Ladich Jason C Kovacic Manfred Boehm Science Translational Medicine 12 Mar 2014 227ra34 In vivo endothelial cell fate mapping demonstrates that TGF β signaling is a central pathway regulating the endothelial to mesenchymal transition EndMT during vein graft remodeling Editor s Summary Abstract Full Text PDF Postexposure Protection of Macaques from Vaginal SHIV Infection by Topical Integrase Inhibitors By Charles Dobard Sunita Sharma Urvi M Parikh Rolieria West Andrew Taylor Amy Martin Chou Pong Pau Debra L Hanson Jonathan Lipscomb James Smith Francis Novembre Daria Hazuda J Gerardo Garcia Lerma Walid Heneine Science Translational Medicine 12 Mar 2014 227ra35 Postexposure protection of macaques from SHIV infection by a gel containing integrase inhibitors Editor s Summary Abstract Full Text PDF Intestinal Inhibition of the Na H Exchanger 3 Prevents Cardiorenal Damage in Rats and Inhibits Na Uptake in Humans By Andrew G Spencer Eric D Labonte David P Rosenbaum Craig F Plato Christopher W Carreras Michael R Leadbetter Kenji Kozuka Jill Kohler Samantha Koo McCoy Limin He Noah Bell Jocelyn Tabora Kristin M Joly Marc Navre Jeffrey W Jacobs Dominique Charmot Science Translational Medicine 12 Mar 2014 227ra36 An inhibitor of intestinal NHE3 reduces absorption of dietary sodium in rats and humans and prevents salt induced cardiorenal injury in nephrectomized rats Editor s Summary Abstract Full Text PDF Editors Choice The Serpin Shield By Mercedes Balcells Science Translational Medicine 12 Mar 2014 227ec43 Serpins help breast and lung cancer cells metastasize to the brain by annulling stromal defenses and co opting capillaries Full Text Sifting for Diagnostic Gold By Edward Kai Hua Chow Science Translational Medicine 12 Mar 2014 227ec44 Nanoporous silica thin films can enrich for low abundance serum peptides in clinical samples Full Text Got Milk Antibodies By Mustafa Mahfuz Science Translational Medicine 12 Mar 2014 227ec45 Secreted immunoglobulins in breast milk may promote long term benefits against intestinal inflammatory diseases Full Text Are Two Heads Really Better than One By Goutham Narla Science Translational Medicine 12 Mar 2014 227ec46 The PRKCI and SOX2 oncogenes are coamplified and cooperate to activate Hedgehog signaling in lung squamous cell carcinoma Full Text New Biology Identified by Genetic Analysis of Nonalcoholic Fatty Liver Disease By Benjamin Neale Science Translational Medicine 12 Mar 2014 227ec47 Genetic variation in TM6SF2 predisposes to nonalcoholic fatty liver disease potentially through impairment of

    Original URL path: http://stm.sciencemag.org/content/6/227 (2016-02-10)
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