archive-org.com » ORG » T » TECHLINKCENTER.ORG

Total: 656

Choose link from "Titles, links and description words view":

Or switch to "Titles and links view".
  • Real-Time, Label-Free Protein Secretion Imaging | TechLink
    middle and multiple arrays w cells bottom The Technology The US Naval Research Laboratory NRL has developed a patent pending technique to visualize protein secretions from single cells in real time with a spatial resolution of less than 10 nm Protein secretions are known to play a central role in cellular communication yet secretion dynamics are not well understood since current imaging techniques utilize fluorescent labeling with nonspecific spatial resolution and require time intensive experimental procedures 1 3 days The spatial and temporal characteristics of cellular protein secretions dictate the response of neighboring cells and are critical inputs to processes such as wound healing immune response and angiogenesis The NRL technology provides high spatial resolution protein secretion imaging in real time and integrates seamlessly with standard wide field and confocal light microscopes Protein imaging is enabled through use of a standard glass coverslip containing a lithographically patterned array of gold nanostructures that are functionalized to bind to the protein of interest The secreted proteins may be imaged on a charge coupled device CCD camera due to a shift in localized surface plasmon resonance LSPR of the nanostructures upon binding Through controlled functionalization of the nanostructures secreted proteins may be readily quantified from a wide range of cells including neurons blood cells and epithelial cells among others Benefits Provides real time quantitative measurements of secreted protein concentrations at the single cell level Seamless integration to commercially available light microscopes Widely applicable to commercially available light microscopes The Opportunity US Patent Applications 14 039 326 and 14 207 927 and international patent applications PCT US2013 062189 and PCT US2014 025316 are available for license Collaboration with NRL researchers is available under a Cooperative Research and Development Agreement CRADA Contacts Dr Austin Leach Senior Technology Manager Montana State University TechLink Bozeman Montana austin

    Original URL path: http://techlinkcenter.org/summaries/real-time-label-free-protein-secretion-imaging (2016-02-09)
    Open archived version from archive


  • Generic Background | TechLink
    the Defense and private industry to develop transfer commercialize and transition leading edge technologies images You are here Home Generic Background Main menu Home Licensing Joint R D Technology Summaries Patents SBIR About TechLink Contact Us Search form Search 2016

    Original URL path: http://techlinkcenter.org/images/generic-background (2016-02-09)
    Open archived version from archive

  • Rate Actuated Tether (RAT) Dynamic Strapping Material | TechLink
    include buckle free helmet straps c The Technology The US Army Research Laboratory ARL has developed and tested a patent pending technology that incorporates shear thickening fluid into a dynamic strapping material called RAT Strap The RAT Strap stretches and retracts under normal use in a manner similar to an elastic strap however when subjected to a large force it becomes up to 10x more resistive in a fraction of a second The result is a strap component that self adjusts in size to the user or application stretches to allow comfortable movement during typical use but hardens to provide restraint against impacts or other undesirably large rapid movements ARL s technology is simple consisting of one or more filaments inside a tube filled with a customizable discontinuous shear thickening fluid The dynamic ligament could be applied to numerous products including self adjusting helmet straps that do not require buckles or adjustment slides braces that dynamically protect the user under certain potentially injurious conditions and industrial and military safety gear that is comfortable to wear during typical use but provides enhanced safety and security under adverse conditions Benefits Comfortable Self Adjusting Like elastic the RAT Strap will accommodate a full range of desired motion under normal conditions and contract to its original length or diameter until it form fits to the current user or use profile unlike elastic the straps behave like a rigid strap under high forces to prevent unwanted dynamic motion Broadly Applicable The RAT Strap could be used in a variety of applications including sporting goods safety gear adaptive braces and prosthetics and a range of military protective equipment Simple Cost Effective Design components are few and simple shear thickening fluids are inexpensive The Opportunity Pending US patent application 13 927 985 published as 2014 0015176 is

    Original URL path: http://techlinkcenter.org/summaries/rate-actuated-tether-rat-dynamic-strapping-material (2016-02-09)
    Open archived version from archive

  • Technology Licensing Assistance | TechLink
    products and services using these inventions There is no charge to either DoD labs or companies for these services TechLink has helped establish more than 300 license agreements between DoD labs and companies throughout the United States resulting in the transfer of more than 800 patented or patent pending inventions TechLink currently facilitates over half of all new license agreements between the DoD and industry TechLink assists DoD labs and industry by Screening all DoD patented inventions for commercial viability Marketing selected inventions to industry Helping companies evaluate DoD inventions Helping companies prepare high quality license applications and commercialization plans Facilitating the entire licensing process through the signature phase Helping establish cooperative research and development agreements CRADAs in support of license projects Inventions available for licensing can be found in the Patents area of our website Each patent abstract links to the US Patent and Trademark Office USPTO website where the full patent may be viewed Patents For many DoD inventions we provide technology summaries that succinctly present each technology s key features and benefits development status and applications Technology Summaries If you are interested in learning more about any of the above linked opportunities or wish to discuss the

    Original URL path: http://techlinkcenter.org/licensing (2016-02-09)
    Open archived version from archive

  • Joint Research and Development Opportunities | TechLink
    joint R D projects These projects result in new technologies with both government and commercial applications Benefits include Expediting research and development Developing new commercial opportunities Accessing top experts and facilities Protecting intellectual property rights Establishing productive long term business relationships How TechLink assists Helps identify potential partners for joint R D projects Helps potential partners to define the project s Scope of Work Facilitates the entire agreement process Helps

    Original URL path: http://techlinkcenter.org/crada (2016-02-09)
    Open archived version from archive

  • Technology Summaries | TechLink
    development status and applications of select technologies available for licensing Patent numbers which link to the full patent on the US Patent and Trademark Office USPTO website are included in the technology summaries To browse all of the technology summaries follow the link below or select a link at left to view summaries grouped by category View all available Technology Summaries Main menu Home Licensing Joint R D Technology Summaries

    Original URL path: http://techlinkcenter.org/summaries (2016-02-09)
    Open archived version from archive

  • Patents | TechLink
    patents Our website features over 4 200 active Department of Defense patents potentially available for licensing These are grouped by industry area To browse select the industry area in the category pick list To narrow your search enter specific keywords or patent numbers Click the link below to view all available patents View all available Technology Summaries View all available Patents Main menu Home Licensing Joint R D Technology Summaries

    Original URL path: http://techlinkcenter.org/patents (2016-02-09)
    Open archived version from archive

  • SBIR | TechLink
    and are aimed at companies with 500 or fewer employees TechLink has a long standing program offering professional guidance to help companies compete effectively for DoD SBIR STTR awards TechLink s DoD SBIR STTR Assistance Program Enhances communication with DoD program managers technical points of contact and prime contractors Guides companies through the process Assesses technology relevancy to DoD Offers expert proposal development assistance and review Provides guidance in partnering

    Original URL path: http://techlinkcenter.org/sbir (2016-02-09)
    Open archived version from archive



  •