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  • Adhesin as immunogen against enterotoxigenic Escherichia coli | TechLink
    of immunity and prevention of diarrhea resulting from Escherichia coli The inventive subject matter also relates to the use Escherichia coli adhesins as immunogens and to the construction of conformationally stability and protease resistant Escherichia coli adhesin constructs useful for inducing immunity to Escherichia coli pathogenic bacteria The methods provide for the induction of B cell mediated immunity and for the induction of antibody capable of inhibiting the adherence and

    Original URL path: http://techlinkcenter.org/patents/20060153878 (2016-02-10)
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    the native molecule The recombinant MSP 142 is useful as a diagnostic reagent for use in antibody production and as a vaccine Read more about Recombinant P Falciparum Merozoite Protein 142 Vaccine Screening for disease susceptibility by genotyping the CCR5 and CCR2 genes Patent Identifier 20100021888 Provided are compositions methods and uses for identifying persons at an increased risk of infection by transmission of or accelerated progression of a disease caused by an HIV 1 virus Diagnostic prognostic and combined therapeutic kits are also provided Read more about Screening for disease susceptibility by genotyping the CCR5 and CCR2 genes Composition And Method For The Induction Of Immunity Against Bacillus Cereus Group Bacteria Patent Identifier 20100008950 A composition comprised of one or more bacterial proteins that are conserved among members of Bacillus cereus that is capable of inducing an immune response against members of Bacillus cereus group bacteria The invention also relates to a method of utilizing the composition to induce an immune response Read more about Composition And Method For The Induction Of Immunity Against Bacillus Cereus Group Bacteria Cobalt Amine Based Metal Complex As An Antibacterial Compound Patent Identifier 20100004187 Disclosed herein is a method of administering to a subject suspected of being infected with a bacterium a composition of a cobalt III compound having the formula CoR1R2R3R4R5R6 or a salt thereof and an antibiotic compound Read more about Cobalt Amine Based Metal Complex As An Antibacterial Compound Hardware acceleration for thermodynamically constrained DNA code generation Patent Identifier 20090325820 An apparatus that accelerates the determination of NN free energy of binding estimates for a large number of DNA oligomers using reconfigurable hardware and applies it to the design of high quality DNA code word libraries The invention provides a reconfigurable hardware accelerator and method for implementing a nearest neighbor based free energy calculation Read more about Hardware acceleration for thermodynamically constrained DNA code generation Truncated recombinant major outer membrane protein antigen R56 of orientia tsutsugamushi strains Karp Kato and Gilliam and its use in antibody based detection assays and vaccines Patent Identifier 20090311722 A recombinant refolded non fusion polypeptide expressed from a truncated r56 gene of the causative agent of scrub typhus Orientia tsutsugamushi for the Karp Kato and Gilliam strains has been produced The invention is useful for detecting prior exposure to scrub typhus screening for and or identification of at least one infectious strain similarity i e Read more about Truncated recombinant major outer membrane protein antigen R56 of orientia tsutsugamushi strains Karp Kato and Gilliam and its use in antibody based detection assays and vaccines Compositions and methods for determining immune status Patent Identifier 20090305899 The present invention provides compositions and methods for identifying molecules in samples that bind to molecules associated with pathogenic agents e g infectious agents In certain aspects the invention may be used to identify individuals that have been exposed to one or more pathogenic agent or have generated antibodies in response to one or more pathogenic agent Read more about Compositions

    Original URL path: http://techlinkcenter.org/patents/categories/medical-biotechnology?page=39 (2016-02-10)
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    Identifier 5916224 A tendon repair clip implant system for placement on the dorsal side of a lacerated or torn tendon to allow active range of motion post tendon repair comprises first and second clips Read more about Tendon repair clip implant Method of raising antibodies against E coli of the family CS4 CFA I Patent Identifier 5914114 A consensus peptide of 36 amino acids has been designed which acts as an immunogen raising antibodies against the proteins of all members of the E coli family CS4 CFA 1 While the N terminus of members of this family of organisms shows a high degree of identity the remainder of the sequence of the proteins shows much less homology across the strains Read more about Method of raising antibodies against E coli of the family CS4 CFA I Silicone containing fluoropolymers for controlled release of organic leachants Patent Identifier 5912286 Coating compositions containing leachable biocides are used to protect surfaces in an aquatic environment from fouling from marine organisms Bio fouling Read more about Silicone containing fluoropolymers for controlled release of organic leachants Insert to provide conformal support for the reflective seal of an oxygen mask Patent Identifier 5909732 A mask insert to provide conformal support for the reflective seal of an oxygen mask comprising a formed rim made of a resiliently deformable material which is held in place beneath the reflective seal by a supporting framework which conforms to the contours of the interior surface of the mask Read more about Insert to provide conformal support for the reflective seal of an oxygen mask Diazodenitrification in manufacture of recombinant bacterial biosensors Patent Identifier 5902728 E coli strain JM109 transfected with nitrate reductase gene containing plasmid pIC20RNR1 1 produces diazoluminomelanin when cultured in a medium containing nitrate 3 amino L tyrosine and luminol under suitable metabolic conditions Read more about Diazodenitrification in manufacture of recombinant bacterial biosensors Use of oral interleukin 6 as therapy for hemorrhagic shock Patent Identifier 5895647 A method for ameliorating the effects of hemorrhagic shock in a subject consists of locally administering to the gut of the subject at a selected time during the period of from about 5 hours before blood loss to about 5 hours after blood loss a therapeutic amount of a cytokine Read more about Use of oral interleukin 6 as therapy for hemorrhagic shock Bacterial spore detection and quantification methods Patent Identifier 5876960 The invented methods are effective for the detection and quantification of bacterial spores in a sample medium A lanthanide such as europium or terbium is combined with a medium to be tested for endospore content Read more about Bacterial spore detection and quantification methods Training device for digital assessment of intraocular pressure Patent Identifier 5868580 A training device for digital assessment of intraocular pressure IOP that ncludes a body top bottom cover and two legs The body contains ten cylindrical cavities the depth of each cavity selected such that the sloped bottom of the cavity intersects with a 0 625

    Original URL path: http://techlinkcenter.org/patents/categories/medical-biotechnology?page=32 (2016-02-10)
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    which dispenses a medicated vapor into the lungs of a patient Patent Identifier 5823434 An aerosol dispensing apparatus comprises a housing which includes a top l having a sharp edged orifice and a speaker assembly mounted on a bottom portion of the housing Read more about Electromechanical driver for an aerosol dispensing apparatus which dispenses a medicated vapor into the lungs of a patient Liposomal formulation Patent Identifier 5820880 Depending on the antigen encapsulated liposomal formulations are subject to instability in the presence of alum Formulations containing a nonionic detergent as a stabilizing agent avoid this instability Read more about Liposomal formulation Protective 17 KDA malaria hepatic and erythrocytic stage immunogen and gene Patent Identifier 5814617 This invention relates to a gene encoding a malaria protein monoclonal antibodies specific for the protein and vaccines for protection against malaria in humans Read more about Protective 17 KDA malaria hepatic and erythrocytic stage immunogen and gene Articulated manipulator for minimally invasive surgery AMMIS Patent Identifier 5810716 A mechanism is described to provide dexterity through articulation The mechanism includes a plurality of concatenated segments for transferring angular rotational motion from a driving device located at its base to the distal end Read more about Articulated manipulator for minimally invasive surgery AMMIS Neutralizing monoclonal antibody against botulinum neurotoxin serotype F Patent Identifier 5807741 Antibodies which neutralize botulinum neurotoxin serotype F are produced using biologically active botulinum neurotoxin instead of toxoid for immunization and exploiting the importance of cross reaction between various serotypes to obtain immune responses or monoclonal antibodies to additional serotypes of interest Read more about Neutralizing monoclonal antibody against botulinum neurotoxin serotype F Cell culture vessel with self maintained atmosphere Patent Identifier 5801054 A cell culture device is described comprising a gas permeable vessel which contains one or more self contained carbon dioxide generators and which is attached to a closure closing a gas permeable cell culture flask Read more about Cell culture vessel with self maintained atmosphere Passive piezoelectric prosthesis for the inner ear Patent Identifier 5800536 A tubular prosthesis formed by an assembly of electrode segments enclosing n elongated inner chamber is inserted into the inner ear of a patient for piezoelectric generation of electrical impulses and localized injection thereof in response to externally generated sound waves Read more about Passive piezoelectric prosthesis for the inner ear Electric field control of epiletiform activity Patent Identifier 5800459 A DC electric field is applied to brain tissue in parallel alignment with urons thereof during periods of brief duration while the tissue is undergoing epileptic activity Read more about Electric field control of epiletiform activity Suppression of epileptiform activity Patent Identifier 5797965 A DC electric field is applied to brain tissue in parallel alignment with urons thereof during periods of brief duration while the tissue is undergoing epileptic activity The electrical field is controllably varied in magnitude to suppress such epilieptic activity Read more about Suppression of epileptiform activity Wound and lavage irrigation cap apparatus and method for using Patent Identifier 5795324 A

    Original URL path: http://techlinkcenter.org/patents/categories/medical-biotechnology?page=33 (2016-02-10)
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    vaccines thereof Lip and cheek retractor Patent Identifier 5730597 The present invention relates to dental devices more particularly to dental devices used for retracting one or more areas in the vicinity of a patient s mouth for purposes of facilitating oral surgery or other intraoral procedures Read more about Lip and cheek retractor Method and apparatus for predicting the efficacy of cardioversion Patent Identifier 5730144 An apparatus and method for predicting the efficacy of cardioversion as a dality for reverting a patient with atrial fibrillation to normal sinus rhythm Blood flow through the patient s atrium is measured converted and processed using nonlinear or chaotic processing to obtain a differential radius signal Read more about Method and apparatus for predicting the efficacy of cardioversion Heated shelter for diver decompression Patent Identifier 5727906 A heated decompression shelter for use by a diver underwater during decomssion at the end of a cold water dive The heated decompression chamber provides a micro environment within an enclosure for thermal protection during decompression stops in cold water some of which can be of relatively long duration following relatively deep dives in near freezing water Read more about Heated shelter for diver decompression Method and apparatus for determining ocular gaze point of regard and fixation duration Patent Identifier 5726916 A method and apparatus for determining ocular gaze point of regard and fixation duration utilizing Electrooculographic measurements and head position and orientation data The Electrooculographic EOG potentials from an unipolar measuring configuration are first amplified filtered and digitized Read more about Method and apparatus for determining ocular gaze point of regard and fixation duration Diffusive sampler system for determining chemical vapor levels Patent Identifier 5726068 Located within the pouch like container is an adsorbent substance for adsorbing the chemical vapor and for providing information with respect to the chemical vapor levels adsorbed thereby In use a plurality of the samplers are adhered to the skin of an individual wearing a protective garment to establish the effectiveness of the garment when subjected to specific chemical vapors Read more about Diffusive sampler system for determining chemical vapor levels Transgenic animal model for autoimmune diseases Patent Identifier 5718883 A transgenic animal whose germ cells and somatic cells contain a transgene including a DNA sequence encoding a CD28 ligand and a tissue specific promoter operably linked to the DNA sequence wherein the tissue specific promoter effects expression of the CD28 ligand in cells of a specific tissue of the animal is disclosed Read more about Transgenic animal model for autoimmune diseases Solid fat nanoemulsions as vaccine delivery vehicles Patent Identifier 5716637 The present invention provides pharmaceutical vaccine compositions that are nanoemulsions of particles having a lipid core which is in a solid or liquid crystalline phase at 25 deg C and which is surrounded by at least one phospholipid bilayer for the parenteral oral intranasal rectal vaginal or topical delivery of both hydrophilic and lipophilic immunogens Read more about Solid fat nanoemulsions as vaccine delivery vehicles Pharmaceutical alpha keto carboxylic acid

    Original URL path: http://techlinkcenter.org/patents/categories/medical-biotechnology?page=34 (2016-02-10)
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    Read more about Transportable life support system Hantavirus vaccine Patent Identifier 5614193 Vaccine formulations for inducing protective immune response to Hantaviruses in humans are disclosed These formulations include an attenuated vaccinia virus vector containing cDNA s encoding Hantavirus nucleocapsid N protein G1 and G2 glycoproteins Methods for the use of these formulations also are disclosed Read more about Hantavirus vaccine Test for quantitative thrombin time Patent Identifier 5476771 A quantitative method for determining the plasma levels of thrombin specific inhibitors is based on the quantitative thrombin time using plasma dilutions excess fibrinogen and thrombin The plasma dilutions and excess fibrinogen act in concert to eliminate the effects that coagulopathies have on standard coagulation tests Read more about Test for quantitative thrombin time Vaccine against ricin toxin Patent Identifier 5453271 It is now possible to immunize susceptible mammals against the pathological effect of exposure to rice including inhalation of ricin by administration of an immunogenic effective amount of ricin toxin sub units including subunits of both the A chain and the B chain of the ricin toxin given separately to provide safe efficacious protection Read more about Vaccine against ricin toxin High efficiency balanced oscillating shuttle pump Patent Identifier 5415532 A pump and a method for pumping liquid or fluid through a pair resilient es includes a shuttle block which partially compresses the tubes in a balanced alternating manner The resilient tubes are held in a parallel relationship with a predetermined space defined therebetween Read more about High efficiency balanced oscillating shuttle pump Nucleotide sequences encoding the expression of a Hantaan virus nucleocapsid protein and G1 and G2 glycoproteins Patent Identifier 5298423 Nucleotide sequences coding for Hantaan virus nucleocapsid protein and glproteins G1 and G2 can be used to produce these proteins for vaccine and diagnostic applications Read more about Nucleotide sequences encoding the expression of a Hantaan virus nucleocapsid protein and G1 and G2 glycoproteins Alkaloids of picralima nitida used for treatment of protozoal diseases Patent Identifier 5290553 A method of preparing substantially purified alkaloids from seeds stems uit rind and bark of a plant selected from Picralima nitida Gongronema latifolia Dorstenia multiradiata Cola attiensis Rothmania withfieldii and Desmodium gangeticum for use in the treatment of protozoal diseases comprising pulverizing said plant a first solvent drying the extracted material and re extracting the Read more about Alkaloids of picralima nitida used for treatment of protozoal diseases Method for the preservation of red blood cells by lyophilization using glycerol or inositol with disaccharides Patent Identifier 5242792 The invention is directed to a composition comprising a permeabilizing agent a preserving agent and a buffered solvent This composition is used to prepare the cells for lyophilization cells and to rehydrate the cells to recover them from lyophilization Read more about Method for the preservation of red blood cells by lyophilization using glycerol or inositol with disaccharides System and Method for Providing Servo Controlled Resuscitation Patent Identifier 20130172849 The present invention provides a system and method for controlling resuscitation in a patient In at

    Original URL path: http://techlinkcenter.org/patents/categories/medical-biotechnology?page=35 (2016-02-10)
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    proximal cuff to the ankle section and foot plate Read more about Dynamic Exoskeletal Orthosis Novel Use And Method Of Rapamycin To Treat Toxic Shock Patent Identifier 20120252834 Rapamycin is used for prevention and treatment of toxic shock The toxic shock is induced for example by a toxin such as Staphylococcal enterotoxin A SEA Staphylococcal enterotoxin B SEB toxic shock syndrome toxin 1 TSST I streptococcal pyrogenic exotoxin A SPEA and streptococcal pyrogenic exotoxin C SPEC Read more about Novel Use And Method Of Rapamycin To Treat Toxic Shock Monoclonal Antibodies Against Glycoprotein Of Ebola Sudan Boniface Virus Patent Identifier 20120164153 We disclose Ebola Sudan Boniface virus GP Monoclonal antibodies epitopes recognized by these monoclonal antibodies and the sequences of the variable regions of some of these antibodies Read more about Monoclonal Antibodies Against Glycoprotein Of Ebola Sudan Boniface Virus Method And Device For Detection Of Bioavailable Drug Concentration In A Fluid Sample Patent Identifier 20120116195 The invention relates to a method for the controlled delivery of a drug as a function of bioavailable drug concentration a sensor device for detecting bioavailable drug concentration and a delivery device that controls delivery of the drug based on the real time detection of bioavailable drug concentration Read more about Method And Device For Detection Of Bioavailable Drug Concentration In A Fluid Sample Compositions and Methods for Determining Immune Status Patent Identifier 20120094861 The present invention provides compositions and methods for identifying molecules in samples that bind to molecules associated with pathogenic agents e g infectious agents In certain aspects the invention may be used to identify individuals that have been exposed to one or more pathogenic agent or have generated antibodies in response to one or more pathogenic agent Read more about Compositions and Methods for Determining Immune Status Plasmodium Falciparum Antigens And Methods Of Use Patent Identifier 20120015401 The subject invention provides novel Plasmodium falciparum antigens and novel polynucleotides encoding these antigens Also provided by the subject invention are methods of using these antigens and polynucleotides Read more about Plasmodium Falciparum Antigens And Methods Of Use Malaria prime boost vaccines Patent Identifier 20120014994 Described are vaccine regimens in which specific prime boost regimens are applied using low neutralized recombinant adenoviral vectors harboring nucleic acids encoding antigens from Plasmodium falciparum and purified recombinant protein vaccines such as RTS S in the context of appropriate adjuvants Read more about Malaria prime boost vaccines Burn Patient Resuscitation System Patent Identifier 20110230824 A method and system for operating a semi closed loop and or a closed loop resuscitation of a burn patient in view of patient information and other physiological data gathered as part of the method and or by the system Read more about Burn Patient Resuscitation System Compositions And Methods For Silencing Ebola Virus Gene Expression Patent Identifier 20110201667 The present invention provides compositions comprising therapeutic nucleic acids e g interfering RNA such as siRNA that target Ebola virus EBOV gene expression and methods of using such compositions to silence EBOV gene expression

    Original URL path: http://techlinkcenter.org/patents/categories/medical-biotechnology?page=36 (2016-02-10)
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    as a Potential Therapeutic Against HIV and or Ebola Virus Psoralen Inactivated Viral Vaccine And Method Of Preparation Patent Identifier 20110014233 A method to prepare inactivate viral vaccine by exposing the virus to a predetermined concentration of an inactivating psoralen and a preselected intensity of ultraviolet radiation for a time period sufficiently long to render the virus non infectious but less than that which would result in degradation of its antigenic characteristics Read more about Psoralen Inactivated Viral Vaccine And Method Of Preparation Puumala Virus Full Length M Segment Based Dna Vaccines Patent Identifier 20100323024 The invention contemplates a new synthetic codon optimized Puumala virus PUUV full length M gene open reading frame ORF that encodes a unique consensus amino acid sequence The PUUV ORF was cloned into a plasmid to form the first stable PUUV full length M gene that elicits neutralizing antibodies Read more about Puumala Virus Full Length M Segment Based Dna Vaccines Recombinant antigens for diagnosis and prevention of murine typhus Patent Identifier 20100311088 The invention relates to the construction of recombinant immunodominant Rickettsia typhi proteins The invention also relates to a method for the use of the recombinant proteins either singly or in combination in detection and diagnostic assays The proteins can also be used in anti Rickettsia typhi immunogenic formulations Read more about Recombinant antigens for diagnosis and prevention of murine typhus Anti Adhesin Based Passive Immunoprophlactic Patent Identifier 20100297141 The invention relates to an immunogenic composition and method of the immunogenic composition for the production and administration of a passive immunoprophylactic against enterotoxigenic Escherichia coli The immunoprophylactic is made collecting anti adhesin in the colostrum or milk of vaccinated domesticated animals such as cows Read more about Anti Adhesin Based Passive Immunoprophlactic Activation of natural killer NK cells and methods of use Patent Identifier 20100285055 The present invention relates to filovirus VLPs and their use in activating innate immunity specifically natural killer cells and in enhancing an immune response to an antigen in an animal Read more about Activation of natural killer NK cells and methods of use Recombinant light chains of botulinum neurotoxins and light chain fusion proteins for use in research and clinical therapy Patent Identifier 20100273211 Botulinum neurotoxins the most potent of all toxins induce lethal neuromuscular paralysis by inhibiting exocytosis at the neuromuscular junction The light chains LC of these dichain neurotoxins are a new class of zinc endopeptidases that specifically cleave the synaptosomal proteins SNAP 25 VAMP or syntaxin at discrete sites Read more about Recombinant light chains of botulinum neurotoxins and light chain fusion proteins for use in research and clinical therapy CR 2 Binding Peptide P28 as Molecular Adjuvant for DNA Vaccines Patent Identifier 20100255075 The invention is an DNA vaccine and method of use thereof for modulating the immune response against the circumsporozoite protein CSP of malaria parasites using the CR2 binding motifs of C3d especially p28 Read more about CR 2 Binding Peptide P28 as Molecular Adjuvant for DNA Vaccines Isolation and Purification of

    Original URL path: http://techlinkcenter.org/patents/categories/medical-biotechnology?page=37 (2016-02-10)
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